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Ring-opening of N-tosyl aziridines by sulphur-stabilized nucleophiles

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Ring-opening of N-tosyl aziridines by sulphur-stabilized nucleophiles. / Osborn, Helen M.I.; Sweeney, J. B.; Howson, Bill.
In: SYNLETT, Vol. 1993, No. 9, 01.09.1993, p. 675-676.

Research output: Contribution to Journal/MagazineJournal articlepeer-review

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Osborn HMI, Sweeney JB, Howson B. Ring-opening of N-tosyl aziridines by sulphur-stabilized nucleophiles. SYNLETT. 1993 Sept 1;1993(9):675-676. doi: 10.1055/s-1993-22568

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Osborn, Helen M.I. ; Sweeney, J. B. ; Howson, Bill. / Ring-opening of N-tosyl aziridines by sulphur-stabilized nucleophiles. In: SYNLETT. 1993 ; Vol. 1993, No. 9. pp. 675-676.

Bibtex

@article{4866f4fb867d4962adbbafed20defd62,
title = "Ring-opening of N-tosyl aziridines by sulphur-stabilized nucleophiles",
abstract = "The novel ring-opening reaction of enantiopure N-activated aziridines 1 with anions 2 derived from 1,3-dithiane proceeds regiospecifically at the carbon of lesser substitution. The ring-opened products 3 may efficiently be converted to homochiral 2-tosylaminocarbonyl compounds 4.",
author = "Osborn, {Helen M.I.} and Sweeney, {J. B.} and Bill Howson",
year = "1993",
month = sep,
day = "1",
doi = "10.1055/s-1993-22568",
language = "English",
volume = "1993",
pages = "675--676",
journal = "SYNLETT",
issn = "0936-5214",
publisher = "Georg Thieme Verlag",
number = "9",

}

RIS

TY - JOUR

T1 - Ring-opening of N-tosyl aziridines by sulphur-stabilized nucleophiles

AU - Osborn, Helen M.I.

AU - Sweeney, J. B.

AU - Howson, Bill

PY - 1993/9/1

Y1 - 1993/9/1

N2 - The novel ring-opening reaction of enantiopure N-activated aziridines 1 with anions 2 derived from 1,3-dithiane proceeds regiospecifically at the carbon of lesser substitution. The ring-opened products 3 may efficiently be converted to homochiral 2-tosylaminocarbonyl compounds 4.

AB - The novel ring-opening reaction of enantiopure N-activated aziridines 1 with anions 2 derived from 1,3-dithiane proceeds regiospecifically at the carbon of lesser substitution. The ring-opened products 3 may efficiently be converted to homochiral 2-tosylaminocarbonyl compounds 4.

U2 - 10.1055/s-1993-22568

DO - 10.1055/s-1993-22568

M3 - Journal article

AN - SCOPUS:0002145831

VL - 1993

SP - 675

EP - 676

JO - SYNLETT

JF - SYNLETT

SN - 0936-5214

IS - 9

ER -