Home > Research > Publications & Outputs > Role of transdermal potential difference during...

Electronic data

Links

Text available via DOI:

View graph of relations

Role of transdermal potential difference during intophoretic drug delivery.

Research output: Contribution to journalJournal articlepeer-review

Published

Standard

Role of transdermal potential difference during intophoretic drug delivery. / Bandrivskyy, Andriy; Bernjak, Alan; McClintock, Peter V. E.

In: IEEE Transactions on Biomedical Engineering, Vol. 51, No. 9, 09.2004, p. 1683-1685.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Bandrivskyy, A, Bernjak, A & McClintock, PVE 2004, 'Role of transdermal potential difference during intophoretic drug delivery.', IEEE Transactions on Biomedical Engineering, vol. 51, no. 9, pp. 1683-1685. https://doi.org/10.1109/TBME.2004.828039

APA

Vancouver

Author

Bandrivskyy, Andriy ; Bernjak, Alan ; McClintock, Peter V. E. / Role of transdermal potential difference during intophoretic drug delivery. In: IEEE Transactions on Biomedical Engineering. 2004 ; Vol. 51, No. 9. pp. 1683-1685.

Bibtex

@article{8b1a047f229045a89bbec4d9f1b50ac5,
title = "Role of transdermal potential difference during intophoretic drug delivery.",
abstract = "Potential differences have been measured during transdermal iontophoresis in order to establish the effect of voltage, as opposed to current, on cutaneous blood flow. It is known that, even in the absence of drugs, the iontophoresis current can sometimes produce increased blood flow. The role of voltage in this process is studied through single-ended measurements (between electrode and body) of the potential difference during iontophoresis with 100-/spl mu/A, 20-s current pulses through deionized water, saturated 20.4% NaCl solution, 1 % acetylcholine, and 1 % sodium nitroprusside. It is found that the voltage needed to deliver the current varied by orders of magnitudes less than the differences in the conductance of these different electrolytes, and it is concluded that, at least for the present current protocol, the voltage as such is not an important factor in increasing the blood flow.",
author = "Andriy Bandrivskyy and Alan Bernjak and McClintock, {Peter V. E.}",
note = "{"}{\textcopyright}2004 IEEE. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from the IEEE.{"} {"}This material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders. All persons copying this information are expected to adhere to the terms and constraints invoked by each author's copyright. In most cases, these works may not be reposted without the explicit permission of the copyright holder.{"}",
year = "2004",
month = sep,
doi = "10.1109/TBME.2004.828039",
language = "English",
volume = "51",
pages = "1683--1685",
journal = "IEEE Transactions on Biomedical Engineering",
issn = "0018-9294",
publisher = "IEEE Computer Society",
number = "9",

}

RIS

TY - JOUR

T1 - Role of transdermal potential difference during intophoretic drug delivery.

AU - Bandrivskyy, Andriy

AU - Bernjak, Alan

AU - McClintock, Peter V. E.

N1 - "©2004 IEEE. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from the IEEE." "This material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders. All persons copying this information are expected to adhere to the terms and constraints invoked by each author's copyright. In most cases, these works may not be reposted without the explicit permission of the copyright holder."

PY - 2004/9

Y1 - 2004/9

N2 - Potential differences have been measured during transdermal iontophoresis in order to establish the effect of voltage, as opposed to current, on cutaneous blood flow. It is known that, even in the absence of drugs, the iontophoresis current can sometimes produce increased blood flow. The role of voltage in this process is studied through single-ended measurements (between electrode and body) of the potential difference during iontophoresis with 100-/spl mu/A, 20-s current pulses through deionized water, saturated 20.4% NaCl solution, 1 % acetylcholine, and 1 % sodium nitroprusside. It is found that the voltage needed to deliver the current varied by orders of magnitudes less than the differences in the conductance of these different electrolytes, and it is concluded that, at least for the present current protocol, the voltage as such is not an important factor in increasing the blood flow.

AB - Potential differences have been measured during transdermal iontophoresis in order to establish the effect of voltage, as opposed to current, on cutaneous blood flow. It is known that, even in the absence of drugs, the iontophoresis current can sometimes produce increased blood flow. The role of voltage in this process is studied through single-ended measurements (between electrode and body) of the potential difference during iontophoresis with 100-/spl mu/A, 20-s current pulses through deionized water, saturated 20.4% NaCl solution, 1 % acetylcholine, and 1 % sodium nitroprusside. It is found that the voltage needed to deliver the current varied by orders of magnitudes less than the differences in the conductance of these different electrolytes, and it is concluded that, at least for the present current protocol, the voltage as such is not an important factor in increasing the blood flow.

U2 - 10.1109/TBME.2004.828039

DO - 10.1109/TBME.2004.828039

M3 - Journal article

VL - 51

SP - 1683

EP - 1685

JO - IEEE Transactions on Biomedical Engineering

JF - IEEE Transactions on Biomedical Engineering

SN - 0018-9294

IS - 9

ER -