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Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
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TY - JOUR
T1 - Selective, radical-free activation of benzylic C-H bonds in methylarenes
AU - Chan, A.P.Y.
AU - Jakoobi, M.
AU - Wang, C.
AU - Tian, Y.
AU - Halcovitch, N.
AU - Boulatov, R.
AU - Sergeev, A.G.
PY - 2021/8/18
Y1 - 2021/8/18
N2 - We report rare examples of exclusive benzylic C-H oxidative addition in industrially important methylarenes using simple η4-arene iridium complexes. Mechanistic studies showed that coordinatively unsaturated η2-arene intermediates are responsible for the selective activation of benzylic, not aromatic C-H bonds and formation of stable benzyl complexes after trapping with a phosphine ligand.
AB - We report rare examples of exclusive benzylic C-H oxidative addition in industrially important methylarenes using simple η4-arene iridium complexes. Mechanistic studies showed that coordinatively unsaturated η2-arene intermediates are responsible for the selective activation of benzylic, not aromatic C-H bonds and formation of stable benzyl complexes after trapping with a phosphine ligand.
KW - Iridium compounds
KW - Ligands
KW - Phosphorus compounds
KW - Benzylic
KW - C-H bond
KW - C-H oxidative
KW - Co-ordinatively unsaturated
KW - Iridium complex
KW - Mechanistic studies
KW - Phosphine ligands
KW - Selective activation
KW - Chemical activation
KW - article
KW - oxidation
U2 - 10.1039/d1cc03445f
DO - 10.1039/d1cc03445f
M3 - Journal article
VL - 57
SP - 7894
EP - 7897
JO - Chemical Communications
JF - Chemical Communications
SN - 1359-7345
IS - 64
ER -