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Self-help cognitive behavior therapy for working women with problematic hot flushes and night sweats (MENOS@Work): A multicenter randomized controlled trial

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Self-help cognitive behavior therapy for working women with problematic hot flushes and night sweats (MENOS@Work) : A multicenter randomized controlled trial. / Hardy, Claire; Griffiths, Amanda; Norton, Sam; Hunter, Myra S.

In: Menopause, Vol. 25, No. 5, 01.05.2018, p. 508-519.

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@article{a7136ff1514245f6a241e6157455632b,
title = "Self-help cognitive behavior therapy for working women with problematic hot flushes and night sweats (MENOS@Work): A multicenter randomized controlled trial",
abstract = "Objective: The aim of the study was to examine the efficacy of an unguided, self-help cognitive behavior therapy (SH-CBT) booklet on hot flush and night sweat (HFNS) problem rating, delivered in a work setting. Methods: Women aged 45 to 60 years, having 10 or more problematic HFNS a week, were recruited to a multicenter randomized controlled trial, via the occupational health/human resources departments of eight organizations. Participants were 1:1 randomized to SH-CBT or no treatment waitlist control (NTWC). The primary outcome was HFNS problem rating; secondary outcomes included HFNS frequency, work and social adjustment, sleep, mood, beliefs and behaviors, and work-related variables (absence, performance, turnover intention, and work impairment due to presenteeism). Intention-to-treat analysis was used, and between-group differences estimated using linear mixed models. Results: A total of 124 women were randomly allocated to SH-CBT (n = 60) and NTWC (n = 64). 104 (84%) were assessed for primary outcome at 6 weeks and 102 (82%) at 20 weeks. SH-CBT significantly reduced HFNS problem rating at 6 weeks (SH-CBT vs NTWC adjusted mean difference, -1.49; 95% CI, -2.11 to -0.86; P < 0.001) and at 20 weeks (-1.09; 95% CI, -1.87 to -0.31; P < 0.01). SH-CBT also significantly reduced HFNS frequency, improved work and social adjustment; sleep, menopause beliefs, HFNS beliefs/behaviors at 6 and 20 weeks; improved wellbeing and somatic symptoms and reduced work impairment due to menopause-related presenteeism at 20 weeks, compared with the NTWC. There was no difference between groups in other work-related outcomes. Conclusions: A brief, unguided SH-CBT booklet is a potentially effective management option for working women experiencing problematic HFNS.",
keywords = "Cognitive behavior therapy, Hot flushes, Menopausal symptoms, Menopause, RCT, Vasomotor symptoms, Work",
author = "Claire Hardy and Amanda Griffiths and Sam Norton and Hunter, {Myra S.}",
note = "Copyright {\textcopyright} 2018 The North American Menopause Society",
year = "2018",
month = may,
day = "1",
doi = "10.1097/GME.0000000000001048",
language = "English",
volume = "25",
pages = "508--519",
journal = "Menopause",
issn = "1530-0374",
publisher = "Lippincott Williams and Wilkins Ltd.",
number = "5",

}

RIS

TY - JOUR

T1 - Self-help cognitive behavior therapy for working women with problematic hot flushes and night sweats (MENOS@Work)

T2 - A multicenter randomized controlled trial

AU - Hardy, Claire

AU - Griffiths, Amanda

AU - Norton, Sam

AU - Hunter, Myra S.

N1 - Copyright © 2018 The North American Menopause Society

PY - 2018/5/1

Y1 - 2018/5/1

N2 - Objective: The aim of the study was to examine the efficacy of an unguided, self-help cognitive behavior therapy (SH-CBT) booklet on hot flush and night sweat (HFNS) problem rating, delivered in a work setting. Methods: Women aged 45 to 60 years, having 10 or more problematic HFNS a week, were recruited to a multicenter randomized controlled trial, via the occupational health/human resources departments of eight organizations. Participants were 1:1 randomized to SH-CBT or no treatment waitlist control (NTWC). The primary outcome was HFNS problem rating; secondary outcomes included HFNS frequency, work and social adjustment, sleep, mood, beliefs and behaviors, and work-related variables (absence, performance, turnover intention, and work impairment due to presenteeism). Intention-to-treat analysis was used, and between-group differences estimated using linear mixed models. Results: A total of 124 women were randomly allocated to SH-CBT (n = 60) and NTWC (n = 64). 104 (84%) were assessed for primary outcome at 6 weeks and 102 (82%) at 20 weeks. SH-CBT significantly reduced HFNS problem rating at 6 weeks (SH-CBT vs NTWC adjusted mean difference, -1.49; 95% CI, -2.11 to -0.86; P < 0.001) and at 20 weeks (-1.09; 95% CI, -1.87 to -0.31; P < 0.01). SH-CBT also significantly reduced HFNS frequency, improved work and social adjustment; sleep, menopause beliefs, HFNS beliefs/behaviors at 6 and 20 weeks; improved wellbeing and somatic symptoms and reduced work impairment due to menopause-related presenteeism at 20 weeks, compared with the NTWC. There was no difference between groups in other work-related outcomes. Conclusions: A brief, unguided SH-CBT booklet is a potentially effective management option for working women experiencing problematic HFNS.

AB - Objective: The aim of the study was to examine the efficacy of an unguided, self-help cognitive behavior therapy (SH-CBT) booklet on hot flush and night sweat (HFNS) problem rating, delivered in a work setting. Methods: Women aged 45 to 60 years, having 10 or more problematic HFNS a week, were recruited to a multicenter randomized controlled trial, via the occupational health/human resources departments of eight organizations. Participants were 1:1 randomized to SH-CBT or no treatment waitlist control (NTWC). The primary outcome was HFNS problem rating; secondary outcomes included HFNS frequency, work and social adjustment, sleep, mood, beliefs and behaviors, and work-related variables (absence, performance, turnover intention, and work impairment due to presenteeism). Intention-to-treat analysis was used, and between-group differences estimated using linear mixed models. Results: A total of 124 women were randomly allocated to SH-CBT (n = 60) and NTWC (n = 64). 104 (84%) were assessed for primary outcome at 6 weeks and 102 (82%) at 20 weeks. SH-CBT significantly reduced HFNS problem rating at 6 weeks (SH-CBT vs NTWC adjusted mean difference, -1.49; 95% CI, -2.11 to -0.86; P < 0.001) and at 20 weeks (-1.09; 95% CI, -1.87 to -0.31; P < 0.01). SH-CBT also significantly reduced HFNS frequency, improved work and social adjustment; sleep, menopause beliefs, HFNS beliefs/behaviors at 6 and 20 weeks; improved wellbeing and somatic symptoms and reduced work impairment due to menopause-related presenteeism at 20 weeks, compared with the NTWC. There was no difference between groups in other work-related outcomes. Conclusions: A brief, unguided SH-CBT booklet is a potentially effective management option for working women experiencing problematic HFNS.

KW - Cognitive behavior therapy

KW - Hot flushes

KW - Menopausal symptoms

KW - Menopause

KW - RCT

KW - Vasomotor symptoms

KW - Work

U2 - 10.1097/GME.0000000000001048

DO - 10.1097/GME.0000000000001048

M3 - Journal article

C2 - 29315132

VL - 25

SP - 508

EP - 519

JO - Menopause

JF - Menopause

SN - 1530-0374

IS - 5

ER -