TY - JOUR

T1 - Sequencing and analysis of the complete genome of Newcastle disease virus isolated from a commercial poultry farm in 2010

AU - Munir, Muhammad

AU - Zohari, Siamak

AU - Abbas, Muhammad

AU - Berg, Mikael

PY - 2012/4/1

Y1 - 2012/4/1

N2 - Newcastle disease virus (NDV) infects wild and domestic birds but causes contagious and lethal disease in domestic poultry. ND is currently endemic in Pakistan, but no complete genome sequence of a Pakistani NDV isolate has been reported. An NDV strain isolated from a commercial poultry farm was completely sequenced. Phylogenetic analysis revealed that the isolate is closely related to genotype VII and, more specifically, to subgenotype VIIb, yet with substantial enough differences to be regarded as new subgenotype (VIIf). These findings provide insight into the genetic nature of NDV circulating in Pakistan and are useful for both laboratory diagnosis and vaccine development for NDV.

AB - Newcastle disease virus (NDV) infects wild and domestic birds but causes contagious and lethal disease in domestic poultry. ND is currently endemic in Pakistan, but no complete genome sequence of a Pakistani NDV isolate has been reported. An NDV strain isolated from a commercial poultry farm was completely sequenced. Phylogenetic analysis revealed that the isolate is closely related to genotype VII and, more specifically, to subgenotype VIIb, yet with substantial enough differences to be regarded as new subgenotype (VIIf). These findings provide insight into the genetic nature of NDV circulating in Pakistan and are useful for both laboratory diagnosis and vaccine development for NDV.

U2 - 10.1007/s00705-011-1220-8

DO - 10.1007/s00705-011-1220-8

M3 - Journal article

C2 - 22218968

AN - SCOPUS:84859103063

VL - 157

SP - 765

EP - 768

JO - Archives of Virology

JF - Archives of Virology

SN - 0304-8608

IS - 4

ER -