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Spectroscopic ellipsometry-based aptasensor platform for bisphenol a detection

Research output: Contribution to Journal/Magazine › Journal article › peer-review

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Spectroscopic ellipsometry-based aptasensor platform for bisphenol a detection. / Şahin, Samet; Üstündağ, Zafer; Caglayan, Mustafa Oguzhan.
In: Talanta, Vol. 253, 123885, 01.02.2023.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Şahin, S, Üstündağ, Z & Caglayan, MO 2023, 'Spectroscopic ellipsometry-based aptasensor platform for bisphenol a detection', Talanta, vol. 253, 123885. https://doi.org/10.1016/j.talanta.2022.123885

APA

Şahin, S., Üstündağ, Z., & Caglayan, M. O. (2023). Spectroscopic ellipsometry-based aptasensor platform for bisphenol a detection. Talanta, 253, Article 123885. https://doi.org/10.1016/j.talanta.2022.123885

Vancouver

Şahin S, Üstündağ Z, Caglayan MO. Spectroscopic ellipsometry-based aptasensor platform for bisphenol a detection. Talanta. 2023 Feb 1;253:123885. Epub 2022 Aug 28. doi: 10.1016/j.talanta.2022.123885

Author

Şahin, Samet ; Üstündağ, Zafer ; Caglayan, Mustafa Oguzhan. / Spectroscopic ellipsometry-based aptasensor platform for bisphenol a detection. In: Talanta. 2023 ; Vol. 253.

Bibtex

@article{be1a2c1789454a6eb2b6a95f7cb10688,
title = "Spectroscopic ellipsometry-based aptasensor platform for bisphenol a detection",
abstract = "Endocrine-disrupting chemicals (EDC) are pollutants that alter the function of the endocrine system by interfering with hormone biosynthesis, metabolism, or action. In this study, a spectroscopic ellipsometry platform is proposed using aptamers for the sensitive and selective detection of an EDC, 2,2-Bis(4-hydroxyphenyl)propane (Bisphenol A, BPA). Two different BPA-specific aptamers (Anti-BPA1 and Anti-BPA2) were immobilized to silicon wafer chips by the layer-by-layer self-assembly, a detection limit of 215 pM and 36 pM was obtained using the ellipsometric method for Anti-BPA1 and Anti-BPA2, respectively. Sensor specificity was tested with 2,2-Bis(4-hydroxyphenyl)butane and a maximum RSD of 3.8% was obtained. It has been reported that both aptasensors based on spectroscopic ellipsometry exhibit adequate analytical performance.",
keywords = "Aptasensor, Biosensors, Bisphenol a, Spectroscopic ellipsometry",
author = "Samet {\c S}ahin and Zafer {\"U}st{\"u}ndağ and Caglayan, {Mustafa Oguzhan}",
year = "2023",
month = feb,
day = "1",
doi = "10.1016/j.talanta.2022.123885",
language = "English",
volume = "253",
journal = "Talanta",
issn = "0039-9140",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Spectroscopic ellipsometry-based aptasensor platform for bisphenol a detection

AU - Şahin, Samet

AU - Üstündağ, Zafer

AU - Caglayan, Mustafa Oguzhan

PY - 2023/2/1

Y1 - 2023/2/1

N2 - Endocrine-disrupting chemicals (EDC) are pollutants that alter the function of the endocrine system by interfering with hormone biosynthesis, metabolism, or action. In this study, a spectroscopic ellipsometry platform is proposed using aptamers for the sensitive and selective detection of an EDC, 2,2-Bis(4-hydroxyphenyl)propane (Bisphenol A, BPA). Two different BPA-specific aptamers (Anti-BPA1 and Anti-BPA2) were immobilized to silicon wafer chips by the layer-by-layer self-assembly, a detection limit of 215 pM and 36 pM was obtained using the ellipsometric method for Anti-BPA1 and Anti-BPA2, respectively. Sensor specificity was tested with 2,2-Bis(4-hydroxyphenyl)butane and a maximum RSD of 3.8% was obtained. It has been reported that both aptasensors based on spectroscopic ellipsometry exhibit adequate analytical performance.

AB - Endocrine-disrupting chemicals (EDC) are pollutants that alter the function of the endocrine system by interfering with hormone biosynthesis, metabolism, or action. In this study, a spectroscopic ellipsometry platform is proposed using aptamers for the sensitive and selective detection of an EDC, 2,2-Bis(4-hydroxyphenyl)propane (Bisphenol A, BPA). Two different BPA-specific aptamers (Anti-BPA1 and Anti-BPA2) were immobilized to silicon wafer chips by the layer-by-layer self-assembly, a detection limit of 215 pM and 36 pM was obtained using the ellipsometric method for Anti-BPA1 and Anti-BPA2, respectively. Sensor specificity was tested with 2,2-Bis(4-hydroxyphenyl)butane and a maximum RSD of 3.8% was obtained. It has been reported that both aptasensors based on spectroscopic ellipsometry exhibit adequate analytical performance.

KW - Aptasensor

KW - Biosensors

KW - Bisphenol a

KW - Spectroscopic ellipsometry

U2 - 10.1016/j.talanta.2022.123885

DO - 10.1016/j.talanta.2022.123885

M3 - Journal article

AN - SCOPUS:85139859667

VL - 253

JO - Talanta

JF - Talanta

SN - 0039-9140

M1 - 123885

ER -