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Surface roughness-induced absorption acts as an ovarian cancer cells growth sensor-monitor

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Surface roughness-induced absorption acts as an ovarian cancer cells growth sensor-monitor. / Katiyi, Aviad; Zorea, Johnathan ; Halstuch, Aviran et al.
In: Biosensors and Bioelectronics, Vol. 161, 112240, 01.08.2020.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Katiyi, A, Zorea, J, Halstuch, A, Elkabets, M & Karabchevsky, A 2020, 'Surface roughness-induced absorption acts as an ovarian cancer cells growth sensor-monitor', Biosensors and Bioelectronics, vol. 161, 112240. https://doi.org/10.1016/j.bios.2020.112240

APA

Katiyi, A., Zorea, J., Halstuch, A., Elkabets, M., & Karabchevsky, A. (2020). Surface roughness-induced absorption acts as an ovarian cancer cells growth sensor-monitor. Biosensors and Bioelectronics, 161, Article 112240. https://doi.org/10.1016/j.bios.2020.112240

Vancouver

Katiyi A, Zorea J, Halstuch A, Elkabets M, Karabchevsky A. Surface roughness-induced absorption acts as an ovarian cancer cells growth sensor-monitor. Biosensors and Bioelectronics. 2020 Aug 1;161:112240. Epub 2020 Apr 25. doi: 10.1016/j.bios.2020.112240

Author

Katiyi, Aviad ; Zorea, Johnathan ; Halstuch, Aviran et al. / Surface roughness-induced absorption acts as an ovarian cancer cells growth sensor-monitor. In: Biosensors and Bioelectronics. 2020 ; Vol. 161.

Bibtex

@article{761b2d906da8440ba73d15ee8eab1574,
title = "Surface roughness-induced absorption acts as an ovarian cancer cells growth sensor-monitor",
abstract = "Uncontrolled growth of ovarian cancer cells is the fifth leading cause of female cancer deaths since most ovarian cancer patients are diagnosed at an advanced stage of metastatic disease. Here, we report on the sensor for monitoring the cancer treatment efficiency in real-time. We measure the optical interaction between the evanescent fields of microfiber and ovarian cancer inter-cellular medium at different treatment stages. Spectral absorption signatures are correlated with optical micrographs and western blot tests. We found that the treatment of tumor cells with induces both cells growth arrest and alter the spectral lines in a dose-dependent manner. These observations are mediated by surface roughness out of silica glass material, form an essential step toward the development of early detection of response to cancer therapy.",
keywords = "Cancer, In-vitro, Microfiber, Near-infrared, Overtones, Sensor",
author = "Aviad Katiyi and Johnathan Zorea and Aviran Halstuch and Moshe Elkabets and Alina Karabchevsky",
year = "2020",
month = aug,
day = "1",
doi = "10.1016/j.bios.2020.112240",
language = "English",
volume = "161",
journal = "Biosensors and Bioelectronics",
issn = "0956-5663",
publisher = "Elsevier Limited",

}

RIS

TY - JOUR

T1 - Surface roughness-induced absorption acts as an ovarian cancer cells growth sensor-monitor

AU - Katiyi, Aviad

AU - Zorea, Johnathan

AU - Halstuch, Aviran

AU - Elkabets, Moshe

AU - Karabchevsky, Alina

PY - 2020/8/1

Y1 - 2020/8/1

N2 - Uncontrolled growth of ovarian cancer cells is the fifth leading cause of female cancer deaths since most ovarian cancer patients are diagnosed at an advanced stage of metastatic disease. Here, we report on the sensor for monitoring the cancer treatment efficiency in real-time. We measure the optical interaction between the evanescent fields of microfiber and ovarian cancer inter-cellular medium at different treatment stages. Spectral absorption signatures are correlated with optical micrographs and western blot tests. We found that the treatment of tumor cells with induces both cells growth arrest and alter the spectral lines in a dose-dependent manner. These observations are mediated by surface roughness out of silica glass material, form an essential step toward the development of early detection of response to cancer therapy.

AB - Uncontrolled growth of ovarian cancer cells is the fifth leading cause of female cancer deaths since most ovarian cancer patients are diagnosed at an advanced stage of metastatic disease. Here, we report on the sensor for monitoring the cancer treatment efficiency in real-time. We measure the optical interaction between the evanescent fields of microfiber and ovarian cancer inter-cellular medium at different treatment stages. Spectral absorption signatures are correlated with optical micrographs and western blot tests. We found that the treatment of tumor cells with induces both cells growth arrest and alter the spectral lines in a dose-dependent manner. These observations are mediated by surface roughness out of silica glass material, form an essential step toward the development of early detection of response to cancer therapy.

KW - Cancer

KW - In-vitro

KW - Microfiber

KW - Near-infrared

KW - Overtones

KW - Sensor

U2 - 10.1016/j.bios.2020.112240

DO - 10.1016/j.bios.2020.112240

M3 - Journal article

VL - 161

JO - Biosensors and Bioelectronics

JF - Biosensors and Bioelectronics

SN - 0956-5663

M1 - 112240

ER -