Synthesis and properties of amphiphilic networks. 1: the effect of hydration and polymer composition on the adhesion of immunoglobulin-G to poly(laurylmethacrylate-stat-glycerolmonomethacrylate-stat-ethylene-glycol-dimethacrylate) networks.

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Synthesis and properties of amphiphilic networks. 1: the effect of hydration and polymer composition on the adhesion of immunoglobulin-G to poly(laurylmethacrylate-stat-glycerolmonomethacrylate-stat-ethylene-glycol-dimethacrylate) networks. / Haigh, R.; Rimmer, S.; Fullwood, Nigel J.
In: Biomaterials, Vol. 21, No. 7, 04.2000, p. 735-739.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Haigh, R, Rimmer, S & Fullwood, NJ 2000, 'Synthesis and properties of amphiphilic networks. 1: the effect of hydration and polymer composition on the adhesion of immunoglobulin-G to poly(laurylmethacrylate-stat-glycerolmonomethacrylate-stat-ethylene-glycol-dimethacrylate) networks.', Biomaterials, vol. 21, no. 7, pp. 735-739. https://doi.org/10.1016/S0142-9612(99)00245-8

APA

Haigh, R., Rimmer, S., & Fullwood, N. J. (2000). Synthesis and properties of amphiphilic networks. 1: the effect of hydration and polymer composition on the adhesion of immunoglobulin-G to poly(laurylmethacrylate-stat-glycerolmonomethacrylate-stat-ethylene-glycol-dimethacrylate) networks. Biomaterials, 21(7), 735-739. https://doi.org/10.1016/S0142-9612(99)00245-8

Vancouver

Haigh R, Rimmer S, Fullwood NJ. Synthesis and properties of amphiphilic networks. 1: the effect of hydration and polymer composition on the adhesion of immunoglobulin-G to poly(laurylmethacrylate-stat-glycerolmonomethacrylate-stat-ethylene-glycol-dimethacrylate) networks. Biomaterials. 2000 Apr;21(7):735-739. doi: 10.1016/S0142-9612(99)00245-8

Author

Haigh, R. ; Rimmer, S. ; Fullwood, Nigel J. / Synthesis and properties of amphiphilic networks. 1: the effect of hydration and polymer composition on the adhesion of immunoglobulin-G to poly(laurylmethacrylate-stat-glycerolmonomethacrylate-stat-ethylene-glycol-dimethacrylate) networks. In: Biomaterials. 2000 ; Vol. 21, No. 7. pp. 735-739.

Bibtex

@article{1ecfdc5e2fed48c8a6562dc0da52ea5c,

title = "Synthesis and properties of amphiphilic networks. 1: the effect of hydration and polymer composition on the adhesion of immunoglobulin-G to poly(laurylmethacrylate-stat-glycerolmonomethacrylate-stat-ethylene-glycol-dimethacrylate) networks.",

abstract = "A series of hydrogels composed of varying fractions of dodecyl methacrylate (DM) and 2,3-dihydroxypropyl methacrylate (GM) were prepared using ethylene glycol dimethacrylate (EGDMA) as the cross-linking agent. The study found that for a series of gels with the same monomer ratio, bulk hydration could be controlled by adjusting the cross-link density. The ability to control cross-link density allowed the preparation of gels with the same bulk hydration but different ratios of the two monomers. The adsorption of IgG to the gels was investigated using ELISA. The aim of the project was to investigate the effect of the bulk hydration and polymer composition on IgG adsorption. The results show that for a series of gels with the same monomer ratio, there is a clear trend towards a reduction in protein adsorption as the bulk hydration and accompanying chain mobility of the gel increases. Studies on gels of the same bulk hydration but differing ratios of monomer show higher protein adsorption as the proportion of GM increases.",

keywords = "Adsorption, IgG, Hydration, Hydrogels",

author = "R. Haigh and S. Rimmer and Fullwood, {Nigel J.}",

year = "2000",

month = apr,

doi = "10.1016/S0142-9612(99)00245-8",

language = "English",

volume = "21",

pages = "735--739",

journal = "Biomaterials",

issn = "0142-9612",

publisher = "PERGAMON-ELSEVIER SCIENCE LTD",

number = "7",

}

RIS

TY - JOUR

T1 - Synthesis and properties of amphiphilic networks. 1: the effect of hydration and polymer composition on the adhesion of immunoglobulin-G to poly(laurylmethacrylate-stat-glycerolmonomethacrylate-stat-ethylene-glycol-dimethacrylate) networks.

AU - Haigh, R.

AU - Rimmer, S.

AU - Fullwood, Nigel J.

PY - 2000/4

Y1 - 2000/4

N2 - A series of hydrogels composed of varying fractions of dodecyl methacrylate (DM) and 2,3-dihydroxypropyl methacrylate (GM) were prepared using ethylene glycol dimethacrylate (EGDMA) as the cross-linking agent. The study found that for a series of gels with the same monomer ratio, bulk hydration could be controlled by adjusting the cross-link density. The ability to control cross-link density allowed the preparation of gels with the same bulk hydration but different ratios of the two monomers. The adsorption of IgG to the gels was investigated using ELISA. The aim of the project was to investigate the effect of the bulk hydration and polymer composition on IgG adsorption. The results show that for a series of gels with the same monomer ratio, there is a clear trend towards a reduction in protein adsorption as the bulk hydration and accompanying chain mobility of the gel increases. Studies on gels of the same bulk hydration but differing ratios of monomer show higher protein adsorption as the proportion of GM increases.

AB - A series of hydrogels composed of varying fractions of dodecyl methacrylate (DM) and 2,3-dihydroxypropyl methacrylate (GM) were prepared using ethylene glycol dimethacrylate (EGDMA) as the cross-linking agent. The study found that for a series of gels with the same monomer ratio, bulk hydration could be controlled by adjusting the cross-link density. The ability to control cross-link density allowed the preparation of gels with the same bulk hydration but different ratios of the two monomers. The adsorption of IgG to the gels was investigated using ELISA. The aim of the project was to investigate the effect of the bulk hydration and polymer composition on IgG adsorption. The results show that for a series of gels with the same monomer ratio, there is a clear trend towards a reduction in protein adsorption as the bulk hydration and accompanying chain mobility of the gel increases. Studies on gels of the same bulk hydration but differing ratios of monomer show higher protein adsorption as the proportion of GM increases.

KW - Adsorption

KW - IgG

KW - Hydration

KW - Hydrogels

U2 - 10.1016/S0142-9612(99)00245-8

DO - 10.1016/S0142-9612(99)00245-8

M3 - Journal article

VL - 21

SP - 735

EP - 739

JO - Biomaterials

JF - Biomaterials

SN - 0142-9612

IS - 7

ER -

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