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Synthesis of Functionalized Isoindolinones via Calcium Catalyzed Generation and Trapping of N-Acyliminium Ions

Research output: Contribution to Journal/Magazine › Journal article › peer-review

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Synthesis of Functionalized Isoindolinones via Calcium Catalyzed Generation and Trapping of N-Acyliminium Ions. / Basson, Ashley J.; McLaughlin, Mark G.
In: The Journal of Organic Chemistry, Vol. 85, No. 8, 17.04.2020, p. 5615-5628.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Basson, AJ & McLaughlin, MG 2020, 'Synthesis of Functionalized Isoindolinones via Calcium Catalyzed Generation and Trapping of N-Acyliminium Ions', The Journal of Organic Chemistry, vol. 85, no. 8, pp. 5615-5628. https://doi.org/10.1021/acs.joc.0c00482

APA

Basson, A. J., & McLaughlin, M. G. (2020). Synthesis of Functionalized Isoindolinones via Calcium Catalyzed Generation and Trapping of N-Acyliminium Ions. The Journal of Organic Chemistry, 85(8), 5615-5628. https://doi.org/10.1021/acs.joc.0c00482

Vancouver

Basson AJ, McLaughlin MG. Synthesis of Functionalized Isoindolinones via Calcium Catalyzed Generation and Trapping of N-Acyliminium Ions. The Journal of Organic Chemistry. 2020 Apr 17;85(8):5615-5628. Epub 2020 Mar 25. doi: 10.1021/acs.joc.0c00482

Author

Basson, Ashley J. ; McLaughlin, Mark G. / Synthesis of Functionalized Isoindolinones via Calcium Catalyzed Generation and Trapping of N-Acyliminium Ions. In: The Journal of Organic Chemistry. 2020 ; Vol. 85, No. 8. pp. 5615-5628.

Bibtex

@article{bf26293184e14618af66faac24c74c02,
title = "Synthesis of Functionalized Isoindolinones via Calcium Catalyzed Generation and Trapping of N-Acyliminium Ions",
abstract = "Herein we report our full investigation into the calcium catalyzed generation and trapping of N-acyliminium ions from readily available 3-hydroxyisoindolinones. We have successfully employed a range of traditional nucleophiles including carbon, nitrogen, and sulfur containing reactive partners. The reaction is tolerant to a wide range of functionalities and provides high value scaffolds in good to excellent yields.",
author = "Basson, {Ashley J.} and McLaughlin, {Mark G.}",
year = "2020",
month = apr,
day = "17",
doi = "10.1021/acs.joc.0c00482",
language = "English",
volume = "85",
pages = "5615--5628",
journal = "The Journal of Organic Chemistry",
number = "8",

}

RIS

TY - JOUR

T1 - Synthesis of Functionalized Isoindolinones via Calcium Catalyzed Generation and Trapping of N-Acyliminium Ions

AU - Basson, Ashley J.

AU - McLaughlin, Mark G.

PY - 2020/4/17

Y1 - 2020/4/17

N2 - Herein we report our full investigation into the calcium catalyzed generation and trapping of N-acyliminium ions from readily available 3-hydroxyisoindolinones. We have successfully employed a range of traditional nucleophiles including carbon, nitrogen, and sulfur containing reactive partners. The reaction is tolerant to a wide range of functionalities and provides high value scaffolds in good to excellent yields.

AB - Herein we report our full investigation into the calcium catalyzed generation and trapping of N-acyliminium ions from readily available 3-hydroxyisoindolinones. We have successfully employed a range of traditional nucleophiles including carbon, nitrogen, and sulfur containing reactive partners. The reaction is tolerant to a wide range of functionalities and provides high value scaffolds in good to excellent yields.

U2 - 10.1021/acs.joc.0c00482

DO - 10.1021/acs.joc.0c00482

M3 - Journal article

VL - 85

SP - 5615

EP - 5628

JO - The Journal of Organic Chemistry

JF - The Journal of Organic Chemistry

IS - 8

ER -