Final published version
Licence: CC BY: Creative Commons Attribution 4.0 International License
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
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TY - JOUR
T1 - The first identification of nesfatin-1-expressing neurons in the human bed nucleus of the stria terminalis
AU - Pałasz, Artur
AU - Bogus, Katarzyna
AU - Suszka-Świtek, Aleksandra
AU - Kaśkosz, Andrzej
AU - Saint-Remy, Shirley
AU - Piwowarczyk-Nowak, Aneta
AU - Filipczyk, Łukasz
AU - Worthington, John Joseph
AU - Mordecka-Chamera, Kinga
AU - Kostro, Karol
AU - Bajor, Grzegorz
AU - Wiaderkiewicz, Ryszard
PY - 2019/2/15
Y1 - 2019/2/15
N2 - Neuropeptides are involved in various brain activities being able to control a wide spectrum of higher mental functions.The purpose of this concise structural investigation was to detect the possible immunoreactivity of the novel multifunctional neuropeptide nesfatin-1 within the human bed nucleus of the stria terminalis (BNST). The BNST is involved in themechanism of fear learning, integration of stress and reward circuits, and pathogenesis of addiction. Nesfatin-1-expressingneurons were identified for the first time in several regions of the BNST using both immunohistochemical and fluorescentmethods. This may implicate a potential contribution of this neuropeptide to the BNST-related mechanisms of stress/rewardresponses in the human brain.
AB - Neuropeptides are involved in various brain activities being able to control a wide spectrum of higher mental functions.The purpose of this concise structural investigation was to detect the possible immunoreactivity of the novel multifunctional neuropeptide nesfatin-1 within the human bed nucleus of the stria terminalis (BNST). The BNST is involved in themechanism of fear learning, integration of stress and reward circuits, and pathogenesis of addiction. Nesfatin-1-expressingneurons were identified for the first time in several regions of the BNST using both immunohistochemical and fluorescentmethods. This may implicate a potential contribution of this neuropeptide to the BNST-related mechanisms of stress/rewardresponses in the human brain.
KW - BNST
KW - Nesfatin-1
KW - Brain
KW - Neuropeptides
U2 - 10.1007/s00702-019-01984-3
DO - 10.1007/s00702-019-01984-3
M3 - Journal article
JO - Journal of Neural Transmission
JF - Journal of Neural Transmission
SN - 0300-9564
ER -