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  • journal.pgen.1004416

    Rights statement: © 2014 Toledo-Ortiz et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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The HY5-PIF regulatory module coordinates light and temperature control of photosynthetic gene transcription

Research output: Contribution to journalJournal articlepeer-review

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  • Gabriela Toledo-Ortiz
  • Henrik Johansson
  • Keun Pyo Lee
  • Jordi Bou-Torrent
  • Kelly Stewart
  • Gavin Steel
  • Manuel Rodríguez-Concepción
  • Karen J. Halliday
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Article numbere1004416
<mark>Journal publication date</mark>12/06/2014
<mark>Journal</mark>PLoS Genetics
Issue number6
Volume10
Number of pages14
Publication StatusPublished
<mark>Original language</mark>English

Abstract

The ability to interpret daily and seasonal alterations in light and temperature signals is essential for plant survival. This is particularly important during seedling establishment when the phytochrome photoreceptors activate photosynthetic pigment production for photoautotrophic growth. Phytochromes accomplish this partly through the suppression of phytochrome interacting factors (PIFs), negative regulators of chlorophyll and carotenoid biosynthesis. While the bZIP transcription factor long hypocotyl 5 (HY5), a potent PIF antagonist, promotes photosynthetic pigment accumulation in response to light. Here we demonstrate that by directly targeting a common promoter cis-element (G-box), HY5 and PIFs form a dynamic activation-suppression transcriptional module responsive to light and temperature cues. This antagonistic regulatory module provides a simple, direct mechanism through which environmental change can redirect transcriptional control of genes required for photosynthesis and photoprotection. In the regulation of photopigment biosynthesis genes, HY5 and PIFs do not operate alone, but with the circadian clock. However, sudden changes in light or temperature conditions can trigger changes in HY5 and PIFs abundance that adjust the expression of common target genes to optimise photosynthetic performance and growth.

Bibliographic note

© 2014 Toledo-Ortiz et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.