We investigate the claim that all dwarf spheroidal galaxies (dSphs) reside within halos that share a common, universal mass profile as has been derived for dSphs of the Galaxy. By folding in kinematic information for 25 Andromeda dSphs, more than doubling the previous sample size, we find that a singular mass profile can not be found to fit all the observations well. Further, the best-fit dark matter density profile measured for solely the Milky Way dSphs is marginally discrepant (at just beyond the 1 sigma level) with that of the Andromeda dSphs, where a profile with lower maximum circular velocity, and hence mass, is preferred. The agreement is significantly better when three extreme Andromeda outliers, And XIX, XXI and XXV, all of which have large half-light radii (>600pc) and low velocity dispersions (sigma_v