We propose an experimentally feasible scheme for topological interface engineering and show how it can be used for studies of dynamics of topologically nontrivial interfaces and perforation of defects and textures across such interfaces. The method makes use of the internal spin structure of the atoms together with locally applied control of interaction strengths to create many-particle states with highly complex topological properties. In particular, we consider a constructed coherent interface between topologically distinct phases of spinor Bose-Einstein condensates.