We show that the quotient algebra B ( X ) / I has a unique algebra norm for every closed ideal I of the Banach algebra B ( X ) of bounded operators on X, where X denotes any of the following Banach spaces: • ( ⨁ n ∈ N ℓ 2 n ) c 0 or its dual space ( ⨁ n ∈ N ℓ 2 n ) ℓ 1 , • ( ⨁ n ∈ N ℓ 2 n ) c 0 ⊕ c 0 ( Γ ) or its dual space ( ⨁ n ∈ N ℓ 2 n ) ℓ 1 ⊕ ℓ 1 ( Γ ) for an uncountable cardinal number Γ, • C 0 ( K A ) , the Banach space of continuous functions vanishing at infinity on the locally compact Mrówka space K A induced by an uncountable, almost disjoint family A of infinite subsets of N , constructed such that C 0 ( K A ) admits “few operators”. Equivalently, this result states that every homomorphism from B ( X ) into a Banach algebra is continuous and has closed range. The key step in our proof is to show that the identity operator on a suitably chosen Banach space factors through every operator in B ( X ) ∖ I with control over the norms of the operators used in the factorization. These quantitative factorization results may be of independent interest.