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X-ray phase contrast imaging of biological specimens with femtosecond pulses of betatron radiation from a compact laser plasma wakefield accelerator

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X-ray phase contrast imaging of biological specimens with femtosecond pulses of betatron radiation from a compact laser plasma wakefield accelerator. / Kneip, S.; McGuffey, C.; Dollar, F. et al.
In: Applied Physics Letters, Vol. 99, No. 9, 093701, 29.08.2011.

Research output: Contribution to Journal/MagazineJournal articlepeer-review

Harvard

Kneip, S, McGuffey, C, Dollar, F, Bloom, MS, Chvykov, V, Kalintchenko, G, Krushelnick, K, Maksimchuk, A, Mangles, SPD, Matsuoka, T, Najmudin, Z, Palmer, CAJ, Schreiber, J, Schumaker, W, Thomas, AGR & Yanovsky, V 2011, 'X-ray phase contrast imaging of biological specimens with femtosecond pulses of betatron radiation from a compact laser plasma wakefield accelerator', Applied Physics Letters, vol. 99, no. 9, 093701. https://doi.org/10.1063/1.3627216

APA

Kneip, S., McGuffey, C., Dollar, F., Bloom, M. S., Chvykov, V., Kalintchenko, G., Krushelnick, K., Maksimchuk, A., Mangles, S. P. D., Matsuoka, T., Najmudin, Z., Palmer, C. A. J., Schreiber, J., Schumaker, W., Thomas, A. G. R., & Yanovsky, V. (2011). X-ray phase contrast imaging of biological specimens with femtosecond pulses of betatron radiation from a compact laser plasma wakefield accelerator. Applied Physics Letters, 99(9), Article 093701. https://doi.org/10.1063/1.3627216

Vancouver

Kneip S, McGuffey C, Dollar F, Bloom MS, Chvykov V, Kalintchenko G et al. X-ray phase contrast imaging of biological specimens with femtosecond pulses of betatron radiation from a compact laser plasma wakefield accelerator. Applied Physics Letters. 2011 Aug 29;99(9):093701. doi: 10.1063/1.3627216

Author

Kneip, S. ; McGuffey, C. ; Dollar, F. et al. / X-ray phase contrast imaging of biological specimens with femtosecond pulses of betatron radiation from a compact laser plasma wakefield accelerator. In: Applied Physics Letters. 2011 ; Vol. 99, No. 9.

Bibtex

@article{a3ec941f1e764d8fa125ecb075371a62,
title = "X-ray phase contrast imaging of biological specimens with femtosecond pulses of betatron radiation from a compact laser plasma wakefield accelerator",
abstract = "We show that x-rays from a recently demonstrated table top source of bright, ultrafast, coherent synchrotron radiation [Kneip et al., Nat. Phys. 6, 980 (2010)] can be applied to phase contrast imaging of biological specimens. Our scheme is based on focusing a high power short pulse laser in a tenuous gas jet, setting up a plasma wakefield accelerator that accelerates and wiggles electrons analogously to a conventional synchrotron, but on the centimeter rather than tens of meter scale. We use the scheme to record absorption and phase contrast images of a tetra fish, damselfly and yellow jacket, in particular highlighting the contrast enhancement achievable with the simple propagation technique of phase contrast imaging. Coherence and ultrafast pulse duration will allow for the study of various aspects of biomechanics. (C) 2011 American Institute of Physics. [doi:10.1063/1.3627216]",
keywords = "COMPUTED-TOMOGRAPHY, ELECTRON-BEAMS",
author = "S. Kneip and C. McGuffey and F. Dollar and Bloom, {M. S.} and V. Chvykov and G. Kalintchenko and K. Krushelnick and A. Maksimchuk and Mangles, {S. P. D.} and T. Matsuoka and Z. Najmudin and Palmer, {C. A. J.} and J. Schreiber and W. Schumaker and Thomas, {A. G. R.} and V. Yanovsky",
year = "2011",
month = aug,
day = "29",
doi = "10.1063/1.3627216",
language = "English",
volume = "99",
journal = "Applied Physics Letters",
issn = "0003-6951",
publisher = "American Institute of Physics Inc.",
number = "9",

}

RIS

TY - JOUR

T1 - X-ray phase contrast imaging of biological specimens with femtosecond pulses of betatron radiation from a compact laser plasma wakefield accelerator

AU - Kneip, S.

AU - McGuffey, C.

AU - Dollar, F.

AU - Bloom, M. S.

AU - Chvykov, V.

AU - Kalintchenko, G.

AU - Krushelnick, K.

AU - Maksimchuk, A.

AU - Mangles, S. P. D.

AU - Matsuoka, T.

AU - Najmudin, Z.

AU - Palmer, C. A. J.

AU - Schreiber, J.

AU - Schumaker, W.

AU - Thomas, A. G. R.

AU - Yanovsky, V.

PY - 2011/8/29

Y1 - 2011/8/29

N2 - We show that x-rays from a recently demonstrated table top source of bright, ultrafast, coherent synchrotron radiation [Kneip et al., Nat. Phys. 6, 980 (2010)] can be applied to phase contrast imaging of biological specimens. Our scheme is based on focusing a high power short pulse laser in a tenuous gas jet, setting up a plasma wakefield accelerator that accelerates and wiggles electrons analogously to a conventional synchrotron, but on the centimeter rather than tens of meter scale. We use the scheme to record absorption and phase contrast images of a tetra fish, damselfly and yellow jacket, in particular highlighting the contrast enhancement achievable with the simple propagation technique of phase contrast imaging. Coherence and ultrafast pulse duration will allow for the study of various aspects of biomechanics. (C) 2011 American Institute of Physics. [doi:10.1063/1.3627216]

AB - We show that x-rays from a recently demonstrated table top source of bright, ultrafast, coherent synchrotron radiation [Kneip et al., Nat. Phys. 6, 980 (2010)] can be applied to phase contrast imaging of biological specimens. Our scheme is based on focusing a high power short pulse laser in a tenuous gas jet, setting up a plasma wakefield accelerator that accelerates and wiggles electrons analogously to a conventional synchrotron, but on the centimeter rather than tens of meter scale. We use the scheme to record absorption and phase contrast images of a tetra fish, damselfly and yellow jacket, in particular highlighting the contrast enhancement achievable with the simple propagation technique of phase contrast imaging. Coherence and ultrafast pulse duration will allow for the study of various aspects of biomechanics. (C) 2011 American Institute of Physics. [doi:10.1063/1.3627216]

KW - COMPUTED-TOMOGRAPHY

KW - ELECTRON-BEAMS

U2 - 10.1063/1.3627216

DO - 10.1063/1.3627216

M3 - Journal article

VL - 99

JO - Applied Physics Letters

JF - Applied Physics Letters

SN - 0003-6951

IS - 9

M1 - 093701

ER -