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Dr Leonie Unterholzner

Senior Lecturer in Molecular Immunology

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  1. Published

    Beyond sensing DNA: A role for cGAS in the detection of extracellular cyclic di-nucleotides

    Unterholzner, L., 1/04/2019, In: EMBO Reports. 20, 4, e47970.

    Research output: Contribution to Journal/Magazine › Journal article

  2. Published

    Camouflage and interception: How pathogens evade detection by intracellular nucleic acid sensors

    Unterholzner, L. & Almine, J. F., 03/2019, In: Immunology. 156, 3, p. 217-227 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. Published

    cGAS-independent STING activation in response to DNA damage

    Unterholzner, L. & Dunphy, G., 19/04/2019, In: Molecular & Cellular Oncology. 6, 4, 3 p., e1558682 .

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  4. Published

    Disparate STING signalling as a link between bladder cancer cell innate immune response and the immunostimulatory state of the tumour microenvironment following genotoxic therapies

    Walker, T., Morris, J. & Unterholzner, L., 17/04/2024.

    Research output: Contribution to conference - Without ISBN/ISSN › Poster

  5. Published

    Disparate STING signalling as a link between bladder cancer cell innate immune response and the immunostimulatory state of the tumour microenvironment following genotoxic therapies

    Walker, T. & Unterholzner, L., 7/05/2024.

    Research output: Contribution to conference - Without ISBN/ISSN › Poster

  6. Published

    DNA sensing in cancer: Pro-tumour and anti-tumour functions of cGAS-STING signalling

    Wheeler, O. P. G. & Unterholzner, L., 28/09/2023, In: Essays in Biochemistry. 67, 6, p. 905-918 14 p.

    Research output: Contribution to Journal/Magazine › Review article › peer-review

  7. Published

    IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes

    Almine, J. F., O'Hare, C. A. J., Dunphy, G., Haga, I. R., Naik, R. J., Atrih, A., Connolly, D. J., Taylor, J., Kelsall, I. R., Bowie, A. G., Beard, P. M. & Unterholzner, L., 13/02/2017, In: Nature Communications. 8, 14392.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  8. Published

    IFI16 is an innate immune sensor for intracellular DNA

    Unterholzner, L., Keating, S. E., Baran, M., Horan, K. A., Jensen, S. B., Sharma, S., Sirois, C. M., Jin, T., Latz, E., Xiao, T. S., Fitzgerald, K. A., Paludan, S. R. & Bowie, A. G., 11/2010, In: Nature Immunology. 11, 11, p. 997-1004 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  9. Published

    Innate DNA sensing moves to the nucleus

    Unterholzner, L. & Bowie, A. G., 19/05/2011, In: Cell Host and Microbe. 9, 5, p. 351-353 3 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  10. Published

    Innate immune sensing by cGAS-STING in animals reveals unexpected messengers

    Unterholzner, L., 20/07/2023, In: Cell. 186, 15, p. 3145-3147 3 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

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