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Dr Leonie Unterholzner

Research Fellow/Lecturer

  1. Published

    Beyond sensing DNA: A role for cGAS in the detection of extracellular cyclic di-nucleotides

    Unterholzner, L., 1/04/2019, In : EMBO Reports. 20, 4, e47970.

    Research output: Contribution to journalJournal article

  2. Published

    Camouflage and interception: How pathogens evade detection by intracellular nucleic acid sensors

    Unterholzner, L. & Almine, J. F., 03/2019, In : Immunology. 156, 3, p. 217-227 11 p.

    Research output: Contribution to journalJournal article

  3. Published

    cGAS-independent STING activation in response to DNA damage

    Unterholzner, L. & Dunphy, G., 19/04/2019, In : Molecular & Cellular Oncology. 6, 4, 3 p., e1558682 .

    Research output: Contribution to journalJournal article

  4. Published

    IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes

    Almine, J. F., O'Hare, C. A. J., Dunphy, G., Haga, I. R., Naik, R. J., Atrih, A., Connolly, D. J., Taylor, J., Kelsall, I. R., Bowie, A. G., Beard, P. M. & Unterholzner, L., 13/02/2017, In : Nature Communications. 8, 14392.

    Research output: Contribution to journalJournal article

  5. Published

    IFI16 is an innate immune sensor for intracellular DNA

    Unterholzner, L., Keating, S. E., Baran, M., Horan, K. A., Jensen, S. B., Sharma, S., Sirois, C. M., Jin, T., Latz, E., Xiao, T. S., Fitzgerald, K. A., Paludan, S. R. & Bowie, A. G., 11/2010, In : Nature Immunology. 11, 11, p. 997-1004 8 p.

    Research output: Contribution to journalJournal article

  6. Published

    Innate DNA sensing moves to the nucleus

    Unterholzner, L. & Bowie, A. G., 19/05/2011, In : Cell Host and Microbe. 9, 5, p. 351-353 3 p.

    Research output: Contribution to journalJournal article

  7. Published

    Molecular insights into the interaction of PYM with the Mago-Y14 core of the exon junction complex

    Bono, F., Ebert, J., Unterholzner, L., Güttler, T., Izaurralde, E. & Conti, E., 03/2004, In : EMBO Reports. 5, 3, p. 304-310 7 p.

    Research output: Contribution to journalJournal article

  8. Published

    Non-canonical activation of the DNA sensing adaptor STING by ATM and IFI16 mediates NF-κB signalling after nuclear DNA damage

    Dunphy, G., Flannery, S., Almine, J., Connolly, D., Paulus, C., Jønsson, K., Jakobsen, M., Nevels, M., Bowie, A. & Unterholzner, L., 6/09/2018, In : Molecular Cell. 71, 5, p. 745-760 16 p.

    Research output: Contribution to journalJournal article

  9. Published

    Nonsense-mediated mRNA decay in Drosophila: at the intersection of the yeast and mammalian pathways

    Gatfield, D., Unterholzner, L., Ciccarelli, F. D., Bork, P. & Izaurralde, E., 1/08/2003, In : EMBO Journal. 22, 15, p. 3960-3970 11 p.

    Research output: Contribution to journalJournal article

  10. Published

    Poxvirus targeting of E3 ligase β-TrCP by molecular mimicry: a mechanism to inhibit NF-κB activation and promote immune evasion and virulence

    Mansur, D. S., Maluquer de Motes, C., Unterholzner, L., Sumner, R. P., Ferguson, B. J., Ren, H., Strnadova, P., Bowie, A. G. & Smith, G. L., 02/2013, In : PLoS Pathogens. 9, 2, e1003183.

    Research output: Contribution to journalJournal article

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