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Medical and Pharmaceutical Statistics Research Unit

  1. Published

    Sequential methods for random-effects meta-analysis

    Higgins, J. P. T., Whitehead, A. & Simmonds, M., 30/04/2011, In: Statistics in Medicine. 30, 9, p. 903-921 19 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  2. Published

    Sequential genome-wide association studies for monitoring adverse events in clinical evaluation of new drugs.

    Whitehead, J., Kelly, P. J., Stallard, N., Zhou, Y. & Bowman, C., 30/09/2006, In: Statistics in Medicine. 25, 18, p. 3081-3092 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  3. Published

    Sample size reassessment and hypothesis testing in adaptive survival trials

    Magirr, D., Jaki, T. F., Koenig, F. & Posch, M., 10/02/2016, In: PLoS ONE. 11, 2, 14 p., e0146465.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  4. Published

    Sample size considerations in active-control non-inferiority trials with binary data based on the odds ratio

    Siqueira, A. L., Todd, S. & Whitehead, A., 08/2015, In: Statistical Methods in Medical Research. 24, 4, p. 453-461 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  5. Published

    Recurrent events modelling of haemophilia bleeding events

    Titman, A., Wolfsegger, M. J. & Jaki, T., 1/03/2021, In: Journal of the Royal Statistical Society: Series C (Applied Statistics). 70, 2, p. 351-371 21 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  6. Published

    Recovering Independent Associations in Genetics: A Comparison

    Sperrin, M. & Jaki, T., 08/2012, In: Journal of Computational Biology. 19, 8, p. 978–987 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  7. Published

    Recording lectures as a service in a service course.

    Jaki, T., 11/2009, In: Journal of Statistics Education. 17, 3

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  8. Published
  9. E-pub ahead of print

    Proposing a Core Outcome Set for Physical Activity and Exercise Interventions in People With Rare Neurological Conditions

    Ramdharry, G., Buscemi, V., Boaz, A., Dawes, H., Jaki, T., Jones, F., Marsden, J., Paul, L., Playle, R., Randell, E., Robling, M., Rochester, L. & Busse, M., 21/10/2021, (E-pub ahead of print) In: Frontiers in Rehabilitation Sciences. 2, 13 p., 705474.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  10. Published

    Probabilistic relabelling strategies for the label switching problem in Bayesian mixture models.

    Sperrin, M., Jaki, T. & Wit, E., 07/2010, In: Statistics and Computing. 20, 3, p. 357-366 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  11. Published

    Prior elicitation of the efficacy and tolerability of Methotrexate and Mycophenolate Mofetil in Juvenile Localised Scleroderma

    Desai, Y., Jaki, T., Beresford, M. W., Burnett, T., Eleftheriou, D., Jacobe, H., Leone, V., Li, S., Mozgunov, P., Ramanan, A. V., Torok, K. S., Anderson, M. E., Anton, J., Avcin, T., Felton, J., Foeldvari, I., Laguda, B., McErlane, F., Shaw, L., Zulian, F., & 1 othersPain, C. E., 9/09/2021, In: AMRC Open Research. 3, p. 20 1 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  12. Published

    Principles of dose finding studies in cancer: a comparison of trial designs

    Jaki, T., Clive, S. & Weir, C., 05/2013, In: Cancer Chemotherapy and Pharmacology. 71, 5, p. 1107-1114 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  13. Published

    Practical implementation of the partial ordering continual reassessment method in a Phase I combination‐schedule dose‐finding trial

    Mozgunov, P., Jaki, T., Gounaris, I., Goddemeier, T., Victor, A. & Grinberg, M., 30/12/2022, In: Stat. Med.. 41, 30, p. 5789-5809 21 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  14. Published

    Point estimation for adaptive trial designs I: A methodological review

    Robertson, D. S., Choodari‐Oskooei, B., Dimairo, M., Flight, L., Pallmann, P. & Jaki, T., 30/01/2023, In: Statistics in Medicine. 42, 2, p. 122-145 24 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  15. Published

    Planning multi-arm screening studies within the context of a drug development programme

    Wason, J., Jaki, T. & Stallard, N., 10/09/2013, In: Statistics in Medicine. 32, 20, p. 3424-3435 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  16. Published

    Partial stochastic dominance for the multivariate Gaussian distribution

    Turner, A. & Whitehead, J., 08/2015, In: Statistics and Probability Letters. 103, p. 80-85 6 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  17. Published

    Optimization, refinement and reduction of murine in vivo experiments to assess therapeutic approaches for hemophilia A.

    Baumgartner, B., Jaki, T., Wolfsegger, M. J., Eder, B., Schiviz, A., Schwarz, H. P. & Muchitsch, E. M., 07/2010, In: Laboratory Animals. 44, 3, p. 211-217 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  18. Published

    Optimising the data combination rule for seamless phase II/III clinical trials

    Hampson, L. & Jennison, C., 01/2015, In: Statistics in Medicine. 34, 1, p. 39-58 20 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  19. Published

    Optimal design of multi-arm multi-stage trials

    Wason, J. & Jaki, T., 30/12/2012, In: Statistics in Medicine. 31, 30, p. 4269-4279 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  20. Published

    One- and two-stage design proposals for a phase II trial comparing three active treatments with control using an ordered categorical endpoint.

    Whitehead, J. & Jaki, T., 28/02/2009, In: Statistics in Medicine. 28, 5, p. 828-847 20 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  21. Published

    Not quite normal: Consequences of violating the assumption of normality with regression mixture models

    Van Horn, M. L., Smith, J., Fagan, A., Jaki, T., Maysn, K., Hawkins, D., Feaster, D. & Howe, G., 2012, In: Structural Equation Modeling. 19, 2, p. 227-249 23 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  22. Published

    Non-compartmental estimation of pharmacokinetic parameters in serial sampling designs.

    Wolfsegger, M. J. & Jaki, T., 10/2009, In: Journal of Pharmacokinetics and Pharmacodynamics. 36, 5, p. 479-494

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  23. Published

    Non-compartmental estimation of pharmacokinetic parameters for flexible sampling designs

    Jaki, T. & Wolfsegger, M. J., 2012, In: Statistics in Medicine. 31, 11-12, p. 1059-1073 25 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  24. Published

    Multiplicity: discussion points from the PSI multiplicity expert group

    Phillips, A., Fletcher, C., Atkinson, G., Channon, E., Douiri, A., Jaki, T., Maca, J., Morgan, D., Roger, J. H. & Terrill, P., 09/2013, In: Pharmaceutical Statistics. 12, 5, p. 255-259 5 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  25. Published

    Multi-arm clinical trials with treatment selection: what can be gained and at what price?

    Jaki, T., 04/2015, In: Clinical Investigation. 5, 4, p. 393-399 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

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