Sample size considerations in active-control non-inferiority trials with binary data based on the odds ratio

Siqueira, A. L., Todd, S. & Whitehead, A., 08/2015, In: Statistical Methods in Medical Research. 24, 4, p. 453-461 9 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Cholesterol-lowering effects of oat beta-glucan: a meta-analysis of randomized controlled trials

Whitehead, A., Beck, E. J., Tosh, S. & Wolever, T. M. S., 1/12/2014, In: American Journal of Clinical Nutrition. 100, 6, p. 1413-1421 9 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Mometasone furoate cream reduces acute radiation dermatitis in patients receiving breast radiation therapy: results of a randomized trial

Hindley, A., Zain, Z., Wood, L., Whitehead, A., Sanneh, A., Barber, D. & Hornsby, R., 15/11/2014, In: International Journal of Radiation Oncology - Biology - Physics. 90, 4, p. 748-755 8 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Bridging the gap: a review of dose investigations in paediatric investigation plans

Hampson, L., Herold, R., Posch, M., Saperia, J. & Whitehead, A., 10/2014, In: British Journal of Clinical Pharmacology. 78, 4, p. 898-907 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A Bayesian approach to dose finding studies for cancer therapies: incorporating later cycles of therapy

Sinclair, K. & Whitehead, A., 10/07/2014, In: Statistics in Medicine. 33, 15, p. 2665-2680 16 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Manual vs. integrated automatic load-distributing band CPR with equal survival after out of hospital cardiac arrest: the randomized CIRC trial

Wik, L., Olsen, J.-A., Persse, D., Sterz, F., Lozano Jr, M., Brouwer, M. A., Westfall, M., Souders, C., Malzer, R., Grunsven, P. M. V., Travis, D., Whitehead, A., Herken, U. R. & Lerner, E. B., 06/2014, In: Resuscitation. 85, 6, p. 741-748 8 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A tool to assess the quality of a meta-analysis

Higgins, J. P. T., Lane, P. W., Anagnostelis, B., Anzures-Cabrera, J., Baker, N. F., Cappelleri, J. C., Haughie, S., Hollis, S., Lewis, S. C., Moneuse, P. & Whitehead, A., 12/2013, In: Research Synthesis Methods. 4, 4, p. 351-366 16 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Methodological quality of meta-analyses: matched-pairs comparison over time and between industry sponsored and academic-sponsored reports

Lane, P. W., Higgins, J. P. T., Anagnostelis, B., Anzures-Cabrera, J., Baker, N. F., Cappelleri, J. C., Haughie, S., Hollis, S., Lewis, S. C., Moneuse, P. & Whitehead, A., 12/2013, In: Research Synthesis Methods. 4, 4, p. 342-350 9 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Mometasone Furoate significantly reduces radiation dermatitis in patients undergoing breast radiation therapy: a double-blind randomized control trial in 120 patients

Dunn, K., Hindley, A., Wood, L., Sanneh, A., Barber, D., Whitehead, A. & Zain, Z., 10/2013, In: International Journal of Radiation Oncology - Biology - Physics. 87, 2 Supplement, p. S115 1 p.

Research output: Contribution to Journal/Magazine › Meeting abstract

A bivariate Bayesian dose-finding procedure applied to a seamless phase I/II trial in rheumatoid arthritis

Thygesen, H., Dragalin, V., Whitehead, A. & Whitehead, J., 11/2012, In: Pharmaceutical Statistics. 11, 6, p. 476-484 9 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

An international multicentre randomized controlled trial of G17DT in patients with pancreatic cancer

Gilliam, A., Broome, P., Topuzov, E., Garin, A., Pulay, I., Humphreys, J., Whitehead, A., Takhar, A., Rowlands, B. & Beckingham, I., 04/2012, In: Pancreas. 41, 3, p. 374-379 6 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Investigating the assumption of homogeneity of treatment effects in clincal studies with application to meta-analysis

Julious, S. & Whitehead, A., 01/2012, In: Pharmaceutical Statistics. 11, 1, p. 49-56 8 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Bayesian procedures for phase I/II clinical trials investigating the safety and efficacy of drug combinations

Whitehead, J., Thygesen, H. & Whitehead, A., 20/07/2011, In: Statistics in Medicine. 30, 16, p. 1952-1970 19 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Sequential methods for random-effects meta-analysis

Higgins, J. P. T., Whitehead, A. & Simmonds, M., 30/04/2011, In: Statistics in Medicine. 30, 9, p. 903-921 19 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Design of the circulation improving resuscitation care (CIRC) trial: a new state of the art design for out-of-hospital cardiac arrest research

Lerner, E. B., Persse, D., Souders, C., Sterz, F., Malzer, R., Lozano, M., Westfall, M., Brouwer, M. A., Grunsven, P. M. V., Whitehead, A., Olsen, J.-A., Herken, U. R. & Wik, L., 03/2011, In: Resuscitation. 82, 3, p. 294-299 6 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A Bayesian dose-escalation procedure for phase I clinical trials based only on the assumption of monotonicity.

Whitehead, J., Thygesen, H. & Whitehead, A., 30/07/2010, In: Statistics in Medicine. 29, 17, p. 1808-1824 17 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Meta-analysis of individual patient data versus aggregate data from longitudinal clinical trials.

Jones, A., Riley, R., Williamson, P. & Whitehead, A., 02/2009, In: Clinical Trials. 6, 1, p. 16-27 12 p.

Research output: Contribution to Journal/Magazine › Journal article

Fitting models for the joint action of two drugs using SAS(R).

Whitehead, A., Whitehead, J., Todd, S., Zhou, Y. & Smith, M. K., 10/2008, In: Pharmaceutical Statistics. 7, 4, p. 272-284 13 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Incorporating intermediate binary responses into interim analyses of clinical trials : a comparison of four methods.

Whitehead, A., Sooriyarachchi, M. R., Whitehead, J. & Bolland, K., 10/05/2008, In: Statistics in Medicine. 27, 10, p. 1646-1666 21 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Active-control trials with binary data: a comparison of methods for testing superiority or non-inferiority using the odds ratio.

Siqueira, A., Whitehead, A. & Todd, S., 10/02/2008, In: Statistics in Medicine. 27, 3, p. 353-370 18 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

The effect of selective decontamination of the digestive tract on mortality in multiple trauma patients: a multicenter randomized controlled trial.

The Working Group on Selective Decontamination of the Digestive Tract, 02/2007, In: Intensive Care Medicine. 33, 2, p. 261-270 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Strategies to prevent falls and fractures in hospitals and care homes and effect of cognitive impairment: systematic review and meta- analysis.

Oliver, D., Connelly, J. B., Victor, C. R. & Whitehead, A., 13/01/2007, In: BMJ. 334, 7584, p. 82-85 4 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

The sequential analysis of repeated binary responses: a score test for the case of three time points.

Sooriyarachchi, M. R., Whitehead, J., Whitehead, A. & Bolland, K., 15/07/2006, In: Statistics in Medicine. 25, 13, p. 2196-2214 19 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Incorporating data received after a sequential trial has stopped into the final analysis: implementation and comparison of methods.

Whitehead, J., Bollard, K., Matsushita, T., Sooriyarachchi, M. R. & Whitehead, A., 09/2003, In: Biometrics. 59, 3, p. 701-709 9 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review