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Professor David Allsop

Formerly at Lancaster University

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  1. Published

    Detection of oligomeric forms of α-synuclein protein in human plasma as a potential biomarker for Parkinson’s disease

    El-Agnaf, O. M. A., Salem, S. A., Paleologou, K. E., Curran, M. D., Gibson, M. J., Court, J. A., Schlossmacher, M. G. & Allsop, D., 2006, In: FASEB Journal. 20, 3, p. 419-425 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  2. Published

    Development and automation of a novel [18F]Fprosthetic group, 2-[18F]-fluoro-3-pyridinecarboxaldehyde, and its application to an amino(oxy)-functionalised Aβ peptide

    Morris, O., Gregory, J., Kadirvel, M., Henderson, F., Blykers, A., McMahon, A., Taylor, M. N., Allsop, D., Allan, S., Grigg, J., Boutin, H. & Prenant, C., 10/2016, In: Applied Radiation and Isotopes. 116, p. 120-127 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. Published

    Development of a proteolytically stable retro-inverso peptide inhibitor of β-amyloid oligomerization as a potential novel treatment for Alzheimer's disease

    Taylor, M., Moore, S., Mayes, J., Parkin, E., Beeg, M., Canovi, M., Gobbi, M., Mann, D. M. A. & Allsop, D., 2010, In: Biochemistry. 49, 15, p. 3261-3272 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  4. Published

    Development of proteolytically stable N-methylated peptide inhibitors of aggregation of the amylin peptide implicated in type 2 diabetes

    Obasse, I. C., Taylor, M. N., Fullwood, N. J. & Allsop, D., 6/12/2017, In: Interface Focus. 7, 6, 11 p., 20160127.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  5. Published

    Diagnostic biomarkers for Alzheimer’s disease using non‐invasive specimens

    Paraskevaidi, M., Allsop, D., Karim, S., Martin, F. & Crean, S., 1/06/2020, In: Journal of Clinical Medicine. 9, 6, 19 p., 1673.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  6. Published

    Differential diagnosis of Alzheimer’s disease using spectrochemical analysis of blood

    Paraskevaidi, M., Morais, C., Lima, K., Snowden, J., Saxon, J., Richardson, A., Jones, M., Mann, D., Allsop, D., Martin-Hirsch, P. & Martin, F., 19/09/2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 38, p. E7929–E7938 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  7. Published

    Direct production of reactive oxygen species from aggregating proteins and peptides implicated in the pathogenesis of neurodegenerative diseases.

    Tabner, B. J., Turnbull, S., El-Agnaf, O. M. A. & Allsop, D., 2003, In: Current Medicinal Chemistry Immunology Endocrine and Metabolic Agents. 3, 4, p. 299-308 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  8. Published

    Distinct sites of intracellular production for Alzheimer's disease Aβ40/42 amyloid peptides

    Hartmann, T., Bieger, S. C., Brühl, B., Tienari, P. J., Ida, N., Allsop, D., Roberts, G. W., Masters, C. L., Dotti, C. G., Unsicker, K. & Beyreuther, K., 09/1997, In: Nature Medicine. 3, 9, p. 1016-1020 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  9. Published

    Donepezil for severe Alzheimer's disease.

    Allsop, D., Martin, F., Moore, S. & Fullwood, N. J., 29/07/2006, In: Lancet. 368, 9533, p. 361-362 2 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  10. Published

    Early senile plaques in Alzheimer's disease demonstrated by histochemistry, immunocytochemistry, and electron microscopy

    Ikeda, S., Yanagisawa, N., Allsop, D. & Glenner, G. G., 12/1990, In: Human Pathology. 21, 12, p. 1221-1226 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  11. Published

    Early senile plaques in Down's syndrome brains show a close relationship with cell bodies of neurons

    Allsop, D., Haga, S. I., Haga, C., Ikeda, S. I., Mann, D. M. & Ishii, T., 12/1990, In: Neuropathology and Applied Neurobiology. 15, 6, p. 531-542 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  12. Published

    Early senile plaques in Down's syndrome brains show a close relationship with cell bodies of neurons: evidence for a neuronal origin of senile plaque amyloid

    Allsop, D., Haga, S., Haga, C. & Ishii, T., 1990, Molecular biology and genetics of Alzheimer disease. Miyatake, T., Selkoe, D. J. & Ihara, Y. (eds.). Amsterdam: Elsevier, p. 95-104 10 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Conference contribution/Paper › peer-review

  13. Published

    Effect of aluminium on expression and processing of amyloid precursor protein

    Neill, D., Leake, A., Hughes, D., Keith, A. B., Taylor, G. A., Allsop, D., Rima, B. K., Morris, C., Candy, J. M. & Edwardson, J. A., 15/11/1996, In: Journal of Neuroscience Research. 46, 4, p. 395-403 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  14. Published

    Effect of curcumin-associated and lipid ligand-functionalized nanoliposomes on aggregation of the Alzheimer's Aβ peptide

    Taylor, M., Moore, S., Mourtas, S., Niarakis, A., Re, F., Zona, C., La Ferla, B., Nicotra, F., Masserini, M., Antimisiaris, S. G., Gregori, M. & Allsop, D., 10/2011, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 7, 5, p. 541-550 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  15. Published

    Effects of different isoforms of apoE on aggregation of the α- synuclein protein implicated in Parkinson's disease

    Nouri Emamzadeh, F., Aojula, H., McHugh, P. & Allsop, D., 8/04/2016, In: Neuroscience Letters. 618, p. 146-151 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  16. Published

    Effects of the mutations Glu22 to Gln and Ala21 to Gly on the aggregation of a synthetic fragment of the Alzheimer's amyloid β/A4 peptide

    Clements, A., Walsh, D. M., Williams, C. H. & Allsop, D., 14/10/1993, In: Neuroscience Letters. 161, 1, p. 17-20 4 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  17. Published

    Endopeptidase 3.4.24.11 converts N-1-(R,S)carboxy-3-phenylpropyl-Ala-Ala-Phe-p-carboxyanilide into a potent inhibitor of angiotensin-converting enzyme

    Williams, C. H., Yamamoto, T., Walsh, D. M. & Allsop, D., 15/09/1993, In: Biochemical Journal. 294 , 3, p. 681-684 4 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  18. Published

    Evidence for a neuronal origin of senile plaques in Down's syndrome brains

    Allsop, D., Haga, S., Haga, C. & Ishii, T., 1990, Basic and therapeutic aspects of Alzheimer's and Parkinson's diseases. Nagatsu, T. (ed.). New York: Plenum Press, Vol. 1. p. 83-86 4 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Conference contribution/Paper › peer-review

  19. Published

    Evidence for the derivation of a peptide ligand from the amyloid β protein precursor of Alzheimer's disease

    Allsop, D., Ikeda, S. I. & Glenner, G. G., 1989, Alzheimer's disease and related disorders: proceedings of the First International Conference on Alzheimer's Disease and Related Disorders, held in Las Vegas, Nevada, September 5-9, 1988. Iqbal, K., Wisniewski, H. M. & Winblad, B. (eds.). New York: Alan R. Liss, p. 893-902 10 p. (Progress in clinical and biological research; vol. 317).

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Conference contribution/Paper › peer-review

  20. Published

    Evidence for the derivation of a peptide ligand from the amyloid β-protein precursor of Alzheimer's disease

    Allsop, D., Ikeda, S. & Glenner, G. G., 1989, In: Progress in Clinical and Biological Research. 317, p. 893-902 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  21. Published

    Evidence of amyloid β-protein immunoreactive early plaque lesions in Down's syndrome brains

    Ikeda, S., Yanagisawa, N., Allsop, D. & Glenner, G. G., 1989, In: Laboratory Investigation. 61, 1, p. 133-137 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  22. Published

    Fe(II)-induced DNA damage in α-synuclein-transfected human dopaminergic BE(2)-M17 neuroblastoma cells: detection by the Comet assay.

    Martin, F., Williamson, S. J. M., Paleologou, K. E., Hewitt, R., El-Agnaf, O. M. A. & Allsop, D., 11/2003, In: Journal of Neurochemistry. 87, 3, p. 620-630 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  23. Published

    Fibrillogenesis of β-amyloid

    Allsop, D., Howlett, D., Christie, G. & Karran, E., 08/1998, In: Biochemical Society Transactions. 26, 3, p. 459-463 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  24. Published

    Fluorescence anisotropy: a method for early detection of Alzheimer β-peptide (Aβ) aggregation.

    Allsop, D., Swanson, L., Moore, S., Davies, Y., York, A., El-Agnaf, O. M. A. & Soutar, I., 6/07/2001, In: Biochemical and Biophysical Research Communications. 285, 1, p. 58-63 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  25. Published

    Formation of hydrogen peroxide and hydroxyl radicals from Aβ and α-synuclein as a possible mechanism of cell death in Alzheimer’s disease and Parkinson’s disease.

    Tabner, B. J., Turnbull, S., El-Agnaf, O. M. A. & Allsop, D., 1/06/2002, In: Free Radical Biology and Medicine. 32, 11, p. 1076-1083 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  26. Published

    Galantamine inhibits β-amyloid aggregation and cytotoxicity

    Matharu, B., Gibson, G., Parsons, R., Huckerby, T. N., Moore, S. A., Cooper, L. J., Millichamp, R., Allsop, D. & Austen, B., 15/05/2009, In: Journal of the Neurological Sciences. 280, 1-2, p. 49-58 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  27. Published

    Gelatinase A not α-secretase?

    Walsh, D. M., Williams, C. H., Kennedy, H. E., Allsop, D. & Murphy, G., 1994, In: Nature. 367, 6458, p. 27-28 2 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  28. Published

    Generation of hydrogen peroxide from mutant forms of the prion protein fragment PrP121-231.

    Turnbull, S., Tabner, B. J., Brown, D. R. & Allsop, D., 1/07/2003, In: Biochemistry. 42, 25, p. 7675-7681 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  29. Published

    Gerstmann-Sträussler-Scheinker disease showing β-protein type cerebellar and cerebral amyloid angiopathy

    Ikeda, S. I., Yanagisawa, N., Allsop, D. & Glenner, G. G., 09/1994, In: Acta Neuropathologica. 88, 3, p. 262-266 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  30. Published

    High affinity amyloid peptide β/A4 binding sites and a putative "APP secretase" in rat brain

    Allsop, D., Yamamoto, T., Kametani, F., Miyazaki, N. & Ishii, T., 1991, Proceedings of the XIth International Congress of Neuropathology: The Japanese Society of Neuropathology. Sasaki, Japan, p. 119-127 9 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Conference contribution/Paper › peer-review

  31. Published

    High-molecular-weight β-amyloid oligomers are elevated in cerebrospinal fluid of Alzheimer patients

    Fukumoto, H., Tokuda, T., Kasai, T., Ishigami, N., Hidaka, H., Kondo, M., Allsop, D. & Nakagawa, M., 2010, In: The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 24, 8, p. 2716-2726 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  32. Published

    Human IMR-32 neuroblastoma cells as a model cell line in Alzheimer's disease research

    Neill, D., Hughes, D., Edwardson, J. A., Rima, B. K. & Allsop, D., 1994, In: Journal of Neuroscience Research. 39, 4, p. 482-493 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  33. Published

    Hydrogen peroxide is generated during the very early stages of aggregation of the amyloid peptides implicated in Alzheimer's disease and familial British dementia.

    Tabner, B. J., El-Agnaf, O. M. A., Turnbull, S., German, M. J., Paleologou, K. E., Hayashi, Y., Cooper, L. J., Fullwood, N. & Allsop, D., 28/10/2005, In: Journal of Biological Chemistry. 280, 43, p. 35789-35792 4 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  34. Published

    Hypothesis: soluble Aβ oligomers in association with redox-active metal ions are the optimal generators of reactive oxygen species in Alzheimer's disease

    Tabner, B. J., Mayes, J. & Allsop, D., 8/10/2010, In: International Journal of Alzheimer's Disease. 2011, 6 p., 546380.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  35. Published

    Immunogold labeling of cerebrovascular and neuritic plaque amyloid fibrils in Alzheimer's disease with an anti-β protein monoclonal antibody

    Ikeda, S., Wong, C. W., Allsop, D., Landon, M., Kidd, M. & Glenner, G. G., 1987, In: Laboratory Investigation. 57, 4, p. 446-9 4 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  36. Published

    Immunohistochemical characterization of cerebrovascular amyloid in 46 autopsied cases using antibodies to β protein and cystatin C

    Maruyama, K., Ikeda, S., Ishihara, T., Allsop, D. & Yanagisawa, N., 03/1990, In: Stroke; a journal of cerebral circulation. 21, 3, p. 397-403 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  37. Published

    Immunohistochemical evidence for the derivation of a peptide ligand from the amyloid β-protein precursor of Alzheimer disease

    Allsop, D., Wong, C. W., Ikeda, S., Landon, M., Kidd, M. & Glenner, G. G., 1988, In: Proceedings of the National Academy of Sciences of the United States of America. 85, 8, p. 2790-2794 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  38. Published

    Immunohistochemical studies of cerebrovascular amyloid deposits in brains with cerebral amyloid angiopathy

    Shoji, S., Maruyama, K., Ikeda, S., Yanagisawa, N., Ishihara, T. & Allsop, D., 1989, 1988 Annual Report of the Primary Amyloidosis Research Committee. Tomanaga, M. (ed.). The Ministry of Health and Welfare of Japan, p. 27-30 4 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Chapter

  39. Published

    Increased levels of plasma total tau in adult Down syndrome

    Kasai, T., Tatebe, H., Kondo, M., Ishii, R., Ohmichi, T., Yeung, W. T. E., Morimoto, M., Chiyonobu, T., Terada, N., Allsop, D., Nakagawa, M., Mizuno, T. & Tokuda, T., 30/11/2017, In: PLoS ONE. 12, 11, 12 p., e0188802.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  40. Published

    Increased TDP-43 protein in cerebrospinal fluid of patients with amyotrophic lateral sclerosis

    Kasai, T., Tokuda, T., Ishigami, N., Sasayama, H., Foulds, P., Mitchell, D. J., Mann, D. M. A., Allsop, D. & Nakagawa, M., 2009, In: Acta Neuropathologica. 117, 1, p. 55-62 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  41. Published

    Induction of cellular oxidative stress by the β-amyloid peptide involved in Alzheimer's disease.

    Gibson, G. L., Allsop, D. & Austen, B. M., 2004, In: Protein and Peptide Letters. 11, 3, p. 257-270 14 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  42. Published

    Inflammatory mechanisms in Alzheimer's disease

    Eikelenboom, P., Zhan, S. S., van Gool, W. A. & Allsop, D., 12/1994, In: Trends in Pharmacological Sciences. 15, 12, p. 447-450 4 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  43. Published

    Inherited frontotemporal dementia in 9 British families associated with intronic mutations in the tau gene.

    Pickering-Brown, S. M., Richardson, A. M. T., Snowden, J. S., McDonagh, A., Burns, A., Braudie, W., Baker, M., Yen, S-H., Hardy, J., Hutton, M., Davies, Y., Allsop, D., Craufurd, D., Neary, D. & Mann, D. M. A., 04/2002, In: Brain. 125, 4, p. 732-751 20 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  44. Published

    Introduction to Alzheimer's disease.

    Allsop, D., 2000, Alzheimer's disease : methods and protocols. Hooper, N. (ed.). Totawa, New Jersey: Humana Press, p. 1-21 21 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Chapter

  45. Published

    Isolated senile plaque cores in Alzheimer's disease and Down's syndrome show differences in morphology

    Allsop, D., Kidd, M., Landon, M. & Tomlinson, A., 1986, In: Journal of Neurology, Neurosurgery and Psychiatry. 49, 8, p. 886-892 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  46. Published

    Liposome delivery systems for the treatment of Alzheimer’s disease

    Ross, C., Taylor, M. N., Fullwood, N. J. & Allsop, D., 12/12/2018, In: International Journal of Nanomedicine. 2018, 13, p. 8507-8522 16 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  47. Published

    Magnetite pollution nanoparticles in the human brain

    Maher, B. A., Ahmed, I., Karloukovski, V. V., MacLaren, D., Foulds, P., Allsop, D., Mann, D., Torres-Jardon, R. & Calderon-Garciduenas, L., 27/09/2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 39, p. 10797-10801 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  48. Published

    Mechanism of cerebral amyloidosis in Alzheimer's disease

    Allsop, D., Clements, A., Kennedy, H. E., Walsh, D. M. & Williams, C. H., 1994, Amyloid precursor protein in development, ageing and Alzheimer's disease. Berlin: Springer Verlag, p. 46-59 14 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Conference contribution/Paper › peer-review

  49. Published

    Mechanism of cerebral amyloidosis in Alzheimer's disease

    Howlett, D. R., James, S., Allsop, D. & Roberts, G. W., 1996, Neurobiology of Alzheimer's disease. Dawbarn, D. & Allen, S. J. (eds.). Oxford: BIOS Scientific Publishers, p. 46-59 14 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Chapter

  50. Published

    Metal-dependent generation of reactive oxygen species from amyloid proteins implicated in neurodegenerative disease

    Allsop, D., Mayes, J., Moore, S., Masad, A. & Tabner, B. J., 2008, In: Biochemical Society Transactions. 36, 6, p. 1293-1298 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

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