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Research

Professor David Allsop

Formerly at Lancaster University

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  1. Published

    An investigation into the lipid-binding properties of α-, β- and γ-synucleins in human brain and cerebrospinal fluid

    Salem, S. A., Allsop, D., Mann, D. M. A., Tokuda, T. & El-Agnaf, O. M. A., 19/09/2007, In: Experimental Brain Research. 1170, p. 103-111 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  2. Published

    A monoclonal antibody to common acute lymphoblastic leukemia antigen (neutral endopeptidase) immunostains senile plaques in the brains of patients with Alzheimer's disease

    Sato, M., Ikeda, K., Haga, S., Allsop, D. & Ishii, T., 2/01/1991, In: Neuroscience Letters. 121, 1-2, p. 271-273 3 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. Published

    A preliminary electron microscopic investigation into the interaction between Aβ1-42 peptide and a novel nanoliposome- coupled retro-inverso peptide inhibitor, developed as a potential treatment for Alzheimer's disease

    Sherer, M., Fullwood, N. J., Taylor, M. & Allsop, D., 1/10/2015, In: Journal of Physics: Conference Series. 644, 1, 4 p., 012040.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  4. Published

    Plasma neurofilament light chain: A potential prognostic biomarker of dementia in adult Down syndrome patients

    Shinomoto, M., Kasai, T., Tatebe, H., Kondo, M., Ohmichi, T., Morimoto, M., Chiyonobu, T., Terada, N., Allsop, D., Yokota, I., Mizuno, T. & Tokuda, T., 5/04/2019, In: PLoS ONE. 14, 4, 13 p., e0211575.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  5. Published

    Cerebral spinal fluid biomarker profiles in CNS infection associated with HSV and VZV mimic patterns in Alzheimer’s disease

    Shinomoto, M., Kasai, T., Tatebe, H., Kitani-Morii, F., Ohmichi, T., Fujino, Y., Allsop, D., Mizuno, T. & Tokuda, T., 4/01/2021, In: Translational Neurodegeneration. 10, 1, 3 p., 2.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  6. Published

    Immunohistochemical studies of cerebrovascular amyloid deposits in brains with cerebral amyloid angiopathy

    Shoji, S., Maruyama, K., Ikeda, S., Yanagisawa, N., Ishihara, T. & Allsop, D., 1989, 1988 Annual Report of the Primary Amyloidosis Research Committee. Tomanaga, M. (ed.). The Ministry of Health and Welfare of Japan, p. 27-30 4 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Chapter

  7. Published

    A spectroscopic study of some of the peptidyl radicals formed following hydroxyl radical attack on β-amyloid and α-synuclein.

    Tabner, B. J., Turnbull, S., King, J., Benson, F. E., El-Agnaf, O. M. A. & Allsop, D., 07/2006, In: Free Radical Research. 40, 7, p. 731-739 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  8. Published

    Hydrogen peroxide is generated during the very early stages of aggregation of the amyloid peptides implicated in Alzheimer's disease and familial British dementia.

    Tabner, B. J., El-Agnaf, O. M. A., Turnbull, S., German, M. J., Paleologou, K. E., Hayashi, Y., Cooper, L. J., Fullwood, N. & Allsop, D., 28/10/2005, In: Journal of Biological Chemistry. 280, 43, p. 35789-35792 4 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  9. Published

    Direct production of reactive oxygen species from aggregating proteins and peptides implicated in the pathogenesis of neurodegenerative diseases.

    Tabner, B. J., Turnbull, S., El-Agnaf, O. M. A. & Allsop, D., 2003, In: Current Medicinal Chemistry Immunology Endocrine and Metabolic Agents. 3, 4, p. 299-308 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  10. Published

    Formation of hydrogen peroxide and hydroxyl radicals from Aβ and α-synuclein as a possible mechanism of cell death in Alzheimer’s disease and Parkinson’s disease.

    Tabner, B. J., Turnbull, S., El-Agnaf, O. M. A. & Allsop, D., 1/06/2002, In: Free Radical Biology and Medicine. 32, 11, p. 1076-1083 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  11. Published

    Protein aggregation, metals and oxidative stress in neurodegenerative diseases.

    Tabner, B. J., El-Agnaf, O. M. A., German, M. J., Fullwood, N. J. & Allsop, D., 11/2005, In: Biochemical Society Transactions. 33, 5, p. 1082-1086 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  12. Published

    Production of reactive oxygen species from aggregating proteins implicated in Alzheimer's disease, Parkinson's disease and other neurodegenerative diseases.

    Tabner, B. J., Turnbull, S., El-Agnaf, O. M. A. & Allsop, D., 2001, In: Current Topics in Medicinal Chemistry. 1, p. 483-493 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  13. Published

    The production of hydrogen peroxide during early-stage protein aggregation: a common pathological mechanism in different neurodegenerative diseases?

    Tabner, B., Turnbull, S., Fullwood, N. J., German, M. & Allsop, D., 08/2005, In: Biochemical Society Transactions. 33, 4, p. 548-550 3 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  14. Published

    Hypothesis: soluble Aβ oligomers in association with redox-active metal ions are the optimal generators of reactive oxygen species in Alzheimer's disease

    Tabner, B. J., Mayes, J. & Allsop, D., 8/10/2010, In: International Journal of Alzheimer's Disease. 2011, 6 p., 546380.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  15. Published

    A possible key role for redox-active metal ions and soluble oligomers in neurodegenerative diseases

    Tabner, B., Moore, S., Mayes, J. & Allsop, D., 2013, Brain diseases and metalloproteins. Brown, D. R. (ed.). Boca Raton, Fla.: Pan Stanford, p. 11-32 22 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Chapter

  16. Published

    Quantification of plasma phosphorylated tau to use as a biomarker for brain Alzheimer pathology: pilot case-control studies including patients with Alzheimer’s disease and Down syndrome

    Tatebe, H., Kasai, T., Ohmichi, T., Kishi, Y., Kakeya, T., Waragai, M., Kondo, M., Allsop, D. & Tokuda, T., 4/09/2017, In: Molecular Neurodegeneration. 12, 63, 11 p., 63.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  17. Published

    Effect of curcumin-associated and lipid ligand-functionalized nanoliposomes on aggregation of the Alzheimer's Aβ peptide

    Taylor, M., Moore, S., Mourtas, S., Niarakis, A., Re, F., Zona, C., La Ferla, B., Nicotra, F., Masserini, M., Antimisiaris, S. G., Gregori, M. & Allsop, D., 10/2011, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 7, 5, p. 541-550 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  18. Published

    Development of a proteolytically stable retro-inverso peptide inhibitor of β-amyloid oligomerization as a potential novel treatment for Alzheimer's disease

    Taylor, M., Moore, S., Mayes, J., Parkin, E., Beeg, M., Canovi, M., Gobbi, M., Mann, D. M. A. & Allsop, D., 2010, In: Biochemistry. 49, 15, p. 3261-3272 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  19. Published

    Ultrasonic force microscopy for nanomechanical characterization of early and late-stage amyloid-β peptide aggregation

    Tinker-Mill, C., Mayes, J., Allsop, D. & Kolosov, O., 2014, In: Scientific Reports. 4, 7 p., 4004.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  20. Published

    Decreased α-synuclein in cerebrospinal fluid of aged individuals and subjects with Parkinson’s disease.

    Tokuda, T., Salem, S. A., Allsop, D., Mizuno, T., Nakagawa, M., Qureshi, M. M., Locascio, J. J., Schlossmacher, M. G. & El-Agnaf, O., 13/10/2006, In: Biochemical and Biophysical Research Communications. 349, 1, p. 162-166 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  21. Published

    Copper-dependent generation of hydrogen peroxide from the toxic prion protein fragment PrP106-126.

    Turnbull, S., Tabner, B. J., Brown, D. R. & Allsop, D., 23/01/2003, In: Neuroscience Letters. 336, 3, p. 159-162 4 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  22. Published

    Generation of hydrogen peroxide from mutant forms of the prion protein fragment PrP121-231.

    Turnbull, S., Tabner, B. J., Brown, D. R. & Allsop, D., 1/07/2003, In: Biochemistry. 42, 25, p. 7675-7681 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  23. Published

    Quinacrine acts as an antioxidant and reduces the toxicity of the prion peptide PrP106-126.

    Turnbull, S., Tabner, B. J., Brown, D. R. & Allsop, D., 15/09/2003, In: NeuroReport. 14, 13, p. 1743-1745 3 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  24. Published

    New evidence that the Alzheimer β-amyloid peptide does not spontaneously form free radicals: An ESR study using a series of spin-traps.

    Turnbull, S., Tabner, B. J., El-Agnaf, O. M. A., Twyman, L. J. & Allsop, D., 15/05/2001, In: Free Radical Biology and Medicine. 30, 10, p. 1154-1162 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  25. Published

    α-synuclein implicated in Parkinson’s disease catalyses the formation of hydrogen peroxide in vitro.

    Turnbull, S., Tabner, B. J., Moore, S., Davies, Y., El-Agnaf, O. M. A. & Allsop, D., 15/05/2001, In: Free Radical Biology and Medicine. 30, 10, p. 1163-1170 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

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