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Research

Professor David Allsop

Formerly at Lancaster University

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  1. 2008
  2. Published

    Metal-dependent generation of reactive oxygen species from amyloid proteins implicated in neurodegenerative disease

    Allsop, D., Mayes, J., Moore, S., Masad, A. & Tabner, B. J., 2008, In: Biochemical Society Transactions. 36, 6, p. 1293-1298 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. Published

    TDP-43 protein in plasma may index TDP-43 brain pathology in Alzheimer's disease and frontotemporal lobar degeneration

    Foulds, P., McAuley, E., Gibbons, L., Davidson, Y., Pickering-Brown, S. M., Neary, D., Snowden, J. S., Allsop, D. & Mann, D. M. A., 2008, In: Acta Neuropathologica. 116, 2, p. 141-146 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  4. 2009
  5. Published

    Detection of elevated levels of soluble α-synuclein oligomers in post-mortem brain extracts from patients with dementia with Lewy bodies

    Paleologou, K. E., Kragh, C. L., Mann, D. M. A., Salem, S. A., Al-Shami, R., Allsop, D., Hassan, A. H., Jensen, P. H. & El-Agnaf, O. M. A., 2009, In: Brain. 132, 4, p. 1093-1101 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  6. Published

    Increased TDP-43 protein in cerebrospinal fluid of patients with amyotrophic lateral sclerosis

    Kasai, T., Tokuda, T., Ishigami, N., Sasayama, H., Foulds, P., Mitchell, D. J., Mann, D. M. A., Allsop, D. & Nakagawa, M., 2009, In: Acta Neuropathologica. 117, 1, p. 55-62 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  7. Published

    Plasma phosphorylated-TDP-43 protein levels correlate with brain pathology in frontotemporal lobar degeneration

    Foulds, P., Davidson, Y., Mishra, M., Hobson, D. J., Humphreys, K. M., Taylor, M., Johnson, N., Weintraub, S., Akiyama, H., Arai, T., Hasegawa, M., Bigio, E. H., Benson, F. E., Allsop, D. & Mann, D. M. A., 2009, In: Acta Neuropathologica. 118, 5, p. 647-658 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  8. Published

    Galantamine inhibits β-amyloid aggregation and cytotoxicity

    Matharu, B., Gibson, G., Parsons, R., Huckerby, T. N., Moore, S. A., Cooper, L. J., Millichamp, R., Allsop, D. & Austen, B., 15/05/2009, In: Journal of the Neurological Sciences. 280, 1-2, p. 49-58 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  9. 2010
  10. Published

    Development of a proteolytically stable retro-inverso peptide inhibitor of β-amyloid oligomerization as a potential novel treatment for Alzheimer's disease

    Taylor, M., Moore, S., Mayes, J., Parkin, E., Beeg, M., Canovi, M., Gobbi, M., Mann, D. M. A. & Allsop, D., 2010, In: Biochemistry. 49, 15, p. 3261-3272 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  11. Published

    High-molecular-weight β-amyloid oligomers are elevated in cerebrospinal fluid of Alzheimer patients

    Fukumoto, H., Tokuda, T., Kasai, T., Ishigami, N., Hidaka, H., Kondo, M., Allsop, D. & Nakagawa, M., 2010, In: The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 24, 8, p. 2716-2726 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  12. Published

    Parkinson disease: progress towards a molecular biomarker for Parkinson disease

    Foulds, P., Mann, D. M. A., Mitchell, J. D. & Allsop, D., 07/2010, In: Nature Reviews Neurology. 6, 7, p. 359-361 3 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  13. Published

    Hypothesis: soluble Aβ oligomers in association with redox-active metal ions are the optimal generators of reactive oxygen species in Alzheimer's disease

    Tabner, B. J., Mayes, J. & Allsop, D., 8/10/2010, In: International Journal of Alzheimer's Disease. 2011, 6 p., 546380.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  14. 2011
  15. Published

    Phosphorylated α-synuclein can be detected in blood plasma and is potentially a useful biomarker for Parkinson's disease

    Foulds, P., Mitchell, J. D., Parker, A., Turner, R., Green, G., Diggle, P., Hasegawa, M., Taylor, M., Mann, D. & Allsop, D., 2011, In: The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 25, 12, p. 4127-4137 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  16. Published

    The amylin peptide implicated in type 2 diabetes stimulates copper-mediated carbonyl group and ascorbate radical formation

    Masad, A., Tabner, B. J., Mayes, J. & Allsop, D., 15/08/2011, In: Free Radical Biology and Medicine. 51, 4, p. 869-875 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  17. Published

    Effect of curcumin-associated and lipid ligand-functionalized nanoliposomes on aggregation of the Alzheimer's Aβ peptide

    Taylor, M., Moore, S., Mourtas, S., Niarakis, A., Re, F., Zona, C., La Ferla, B., Nicotra, F., Masserini, M., Antimisiaris, S. G., Gregori, M. & Allsop, D., 10/2011, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 7, 5, p. 541-550 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  18. Published

    TDP-43 pathological changes in early onset familial and sporadic Alzheimer's disease, late onset Alzheimer's disease and Down's Syndrome: association with age, hippocampal sclerosis and clinical phenotype

    Davidson, Y. S., Raby, S., Foulds, P., Robinson, A., Thompson, J. C., Sikkink, S., Yusuf, I., Amin, H., Duplessis, D., Troakes, C., Al-Sarraj, S., Sloan, C., Esiri, M. M., Prasher, V. P., Allsop, D., Neary, D., Pickering-Brown, S. M., Snowden, J. S. & Mann, D. M. A., 12/2011, In: Acta Neuropathologica. 122, 6, p. 703-713 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  19. 2012
  20. Published

    Nanoscale SPM characterisation of nacre aragonite plates and synthetic human amyloid fibres

    Grishin, I., Tinker, C., Allsop, D., Robson, A. & Kolosov, O., 2012, NSTI-Nanotech 2012. Santa Clara, USA: CRC PRESS-TAYLOR & FRANCIS GROUP, Vol. 1. p. 110-113 4 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Conference contribution/Paper › peer-review

  21. Published

    Phosphorylated α-synuclein as a potential biomarker for Parkinson's disease (Editorial)

    Foulds, P., Mann, D. & Allsop, D., 2012, In: Expert Review of Molecular Diagnostics. 12, 2, p. 115-117 3 p.

    Research output: Contribution to Journal/Magazine › Editorial

  22. Published

    Post mortem cerebrospinal fluid α-synuclein levels are raised in multiple system atrophy and distinguish this from the other α-synucleinopathies, Parkinson's disease and Dementia with Lewy bodies

    Foulds, P., Yokota, O., Thurston, A., Davidson, Y., Ahmed, Z., Holton, J., Thompson, J. C., Akiyama, H., Arai, T., Hasegawa, M., Gerhard, A., Allsop, D. & Mann, D. M. A., 01/2012, In: Neurobiology of Disease. 45, 1, p. 188-195 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  23. Published

    Utilization of a multiple antigenic peptide as a calibration standard in the BAN50 single antibody sandwich ELISA for Aß oligomers

    Kasai, T., Tokuda, T., Taylor, M., Nakagawa, M. & Allsop, D., 8/06/2012, In: Biochemical and Biophysical Research Communications. 422, 3, p. 375-380 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  24. 2013
  25. Published

    A novel retro-inverso peptide inhibitor reduces amyloid deposition, oxidation and inflammation and stimulates neurogenesis in the APPswe/PS1ΔE9 mouse model of Alzheimer's Disease

    Parthsarathy, V., McClean, P. L., Hölscher, C., Taylor, M., Tinker, C., Jones, G., Kolosov, O., Salvati, E., Gregori, M., Masserini, M. & Allsop, D., 2013, In: PLoS ONE. 8, 1, 11 p., e54769.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  26. Published

    A possible key role for redox-active metal ions and soluble oligomers in neurodegenerative diseases

    Tabner, B., Moore, S., Mayes, J. & Allsop, D., 2013, Brain diseases and metalloproteins. Brown, D. R. (ed.). Boca Raton, Fla.: Pan Stanford, p. 11-32 22 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Chapter

  27. Published

    A longitudinal study on α-synuclein in blood plasma as a biomarker for Parkinson’s disease

    Foulds, P., Diggle, P., Mitchell, J. D., Parker, A., Hasegawa, M., Masuda-Suzukake, M., Mann, D. M. A. & Allsop, D., 29/08/2013, In: Scientific Reports. 3, 6 p., 2540.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  28. Published

    Correlation of Aβ oligomer levels in matched cerebrospinal fluid and serum samples

    Kasai, T., Tokuda, T., Taylor, M., Kondo, M., Mann, D. M. A., Foulds, P., Nakagawa, M. & Allsop, D., 13/09/2013, In: Neuroscience Letters. 551, p. 17-22 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  29. 2014
  30. Published

    Ultrasonic force microscopy for nanomechanical characterization of early and late-stage amyloid-β peptide aggregation

    Tinker-Mill, C., Mayes, J., Allsop, D. & Kolosov, O., 2014, In: Scientific Reports. 4, 7 p., 4004.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  31. Published

    Amyloid-β fibrils in Alzheimer's Disease are not inert when bound to copper ions but can degrade hydrogen peroxide and generate reactive oxygen species

    Mayes, J., Tinker-Mill, C., Kolosov, O., Zhang, H., Tabner, B. & Allsop, D., 25/04/2014, In: Journal of Biological Chemistry. 289, p. 12052-12062 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  32. Published

    Amyloid β-peptide and Alzheimer's disease

    Allsop, D. & Mayes, J., 18/08/2014, In: Essays in Biochemistry. 56, p. 99-110 12 p., 7.

    Research output: Contribution to Journal/Magazine › Literature review › peer-review

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