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Professor David Allsop

Formerly at Lancaster University

  1. Journal article
  2. Published

    Pick's disease is associated with mutations in the tau gene.

    Pickering-Brown, S., Baker, M., Yen, S-H., Liu, W-K., Hasegawa, M., Cairns, N., Lantos, P. L., Rossor, M., Iwatsubo, T., Davies, Y., Allsop, D., Furlong, R., Owen, F., Hardy, J., David Mann, D. & Hutton, M., 12/2000, In: Annals of Neurology. 48, 6, p. 589-867 279 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  3. Published

    Characterisation of peptidyl boronic acid inhibitors of mammalian 20S and 26S proteasomes and their inhibition of proteasomes in cultured cells

    Gardner, R. C., Assinder, S. J., Christie, G., Mason, G. G. F., Markwell, R., Wadsworth, H., McLaughlin, M., King, R., Chabot-Fletcher, M. C., Breton, J., Allsop, D. & Rivett, A. J., 2000, In: Biochemical Journal. 346, p. 447-454 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  4. Published

    A short synthesis of the β-amyloid (Aβ) aggregation inhibitor 3-p-toluoyl-2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran.

    Twyman, L. J. & Allsop, D., 12/1999, In: Tetrahedron Letters. 40, 52, p. 9383-9384 2 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  5. Published

    Alzheimer's Disease: correlation of the suppression of β-Amyloid peptide secretion from cultured cells with inhibition of the chymotrypsin-like activity of the proteasome

    Christie, G., Markwell, R. E., Gray, C. W., Smith, L., Godfrey, F., Mansfield, F., Wadsworth, H., King, R., McLaughlin, M., Cooper, D. G., Ward, R. V., Howlett, D. R., Hartmann, T., Lichtenthaler, S. F., Beyreuther, K., Underwood, J., Gribble, S. K., Cappai, R., Masters, C. L., Tamaoka, A., & 4 othersGardner, R. L., Rivett, A. J., Karran, E. H. & Allsop, D., 07/1999, In: Journal of Neurochemistry. 73, 1, p. 195-204 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  6. Published

    Biological activity associated with a high molecular weight form of β-amyloid.

    Howlett, D. R., Ward, R. V., Bresciani, L., Jennings, K. H., Christie, G., Allsop, D., Gray, C. W. & Karran, E. H., 1999, In: Alzheimer's Reports. 2, p. 171-177 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  7. Published

    Presenilins: in search of functionality

    Karran, E. H., Allsop, D., Christie, G., Davis, J., Gray, C., Mansfield, F. & Ward, R. V., 08/1998, In: Biochemical Society Transactions. 26, 3, p. 491-496 6 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  8. Published

    Fibrillogenesis of β-amyloid

    Allsop, D., Howlett, D., Christie, G. & Karran, E., 08/1998, In: Biochemical Society Transactions. 26, 3, p. 459-463 5 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  9. Published

    Distinct sites of intracellular production for Alzheimer's disease Aβ40/42 amyloid peptides

    Hartmann, T., Bieger, S. C., Brühl, B., Tienari, P. J., Ida, N., Allsop, D., Roberts, G. W., Masters, C. L., Dotti, C. G., Unsicker, K. & Beyreuther, K., 09/1997, In: Nature Medicine. 3, 9, p. 1016-1020 5 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  10. Published

    Effect of aluminium on expression and processing of amyloid precursor protein

    Neill, D., Leake, A., Hughes, D., Keith, A. B., Taylor, G. A., Allsop, D., Rima, B. K., Morris, C., Candy, J. M. & Edwardson, J. A., 15/11/1996, In: Journal of Neuroscience Research. 46, 4, p. 395-403 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  11. Published

    Aggregation and metal-binding properties of mutant forms of the amyloid Aβ peptide of Alzheimer's disease

    Clements, A., Allsop, D., Walsh, D. M. & Williams, C. H., 02/1996, In: Journal of Neurochemistry. 66, 2, p. 740-747 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  12. Published

    The immunoreactive profile at the N-terminal region of Aβ1-39/40 but not Aβ1-42 changes with transition from monomer/dimer to further peptide aggregates

    Kametani, F., Tanaka, K., Tokuda, T. & Allsop, D., 12/12/1995, In: Brain Research. 703, 1-2, p. 237-241 5 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  13. Published

    Inflammatory mechanisms in Alzheimer's disease

    Eikelenboom, P., Zhan, S. S., van Gool, W. A. & Allsop, D., 12/1994, In: Trends in Pharmacological Sciences. 15, 12, p. 447-450 4 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  14. Published

    Gerstmann-Sträussler-Scheinker disease showing β-protein type cerebellar and cerebral amyloid angiopathy

    Ikeda, S. I., Yanagisawa, N., Allsop, D. & Glenner, G. G., 09/1994, In: Acta Neuropathologica. 88, 3, p. 262-266 5 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  15. Published

    Human IMR-32 neuroblastoma cells as a model cell line in Alzheimer's disease research

    Neill, D., Hughes, D., Edwardson, J. A., Rima, B. K. & Allsop, D., 1994, In: Journal of Neuroscience Research. 39, 4, p. 482-493 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  16. Published

    Variability of β-amyloid protein deposited lesions in Down's syndrome brains

    Ikeda, S., Tokuda, T., Yanagisawa, N., Kametani, F., Ohshima, T. & Allsop, D., 1994, In: The Tohoku Journal of Experimental Medicine. 174, 3, p. 189-198 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  17. Published

    Amyloidosis in Alzheimer's disease

    Allsop, D. & Williams, C. H., 1994, In: Biochemical Society Transactions. 22, 1, p. 171-175 5 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  18. Published

    Aggregation of Alzheimer's peptides

    Clements, A., Walsh, D. M., Williams, C. H. & Allsop, D., 1994, In: Biochemical Society Transactions. 22, 1, p. 16S 1 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  19. Published

    An investigation into the proteolytic cleavage of Alzheimer amyloid precursor protein in PC-12 cells

    Walsh, D. M., Williams, C. H., Kennedy, H. E. & Allsop, D., 1994, In: Biochemical Society Transactions. 22, 1, p. 14S 1 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  20. Published

    Gelatinase A not α-secretase?

    Walsh, D. M., Williams, C. H., Kennedy, H. E., Allsop, D. & Murphy, G., 1994, In: Nature. 367, 6458, p. 27-28 2 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  21. Published

    Effects of the mutations Glu22 to Gln and Ala21 to Gly on the aggregation of a synthetic fragment of the Alzheimer's amyloid β/A4 peptide

    Clements, A., Walsh, D. M., Williams, C. H. & Allsop, D., 14/10/1993, In: Neuroscience Letters. 161, 1, p. 17-20 4 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  22. Published

    Endopeptidase 3.4.24.11 converts N-1-(R,S)carboxy-3-phenylpropyl-Ala-Ala-Phe-p-carboxyanilide into a potent inhibitor of angiotensin-converting enzyme

    Williams, C. H., Yamamoto, T., Walsh, D. M. & Allsop, D., 15/09/1993, In: Biochemical Journal. 294 , 3, p. 681-684 4 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  23. Published

    Secretory form of Alzheimer amyloid precursor protein 695 in human brain lacks β/A4 amyloid immunoreactivity

    Kametani, F., Tanaka, K., Ishii, T., Ikeda, S., Kennedy, H. E. & Allsop, D., 15/03/1993, In: Biochemical and Biophysical Research Communications. 191, 2, p. 392-398 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  24. Published

    Quantification of βA4 protein deposition in the medial temporal lobe: a comparison of Alzheimer's disease and senile dementia of the Lewy body type

    Gentleman, S. M., Williams, B., Royston, M. C., Jagoe, R., Clinton, J., Perry, R. H., Ince, P. G., Allsop, D., Polak, J. M. & Roberts, G. W., 3/08/1992, In: Neuroscience Letters. 142, 1, p. 9-12 4 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  25. Published

    Quantitative differences in the deposition of βA4 protein in the sulci and gyri of frontal and temporal isocortex in Alzheimer's disease

    Gentleman, S. M., Allsop, D., Bruton, C. J., Jagoe, R., Polak, J. M. & Roberts, G. W., 17/02/1992, In: Neuroscience Letters. 136, 1, p. 27-30 4 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  26. Published

    Alzheimer amyloid β/A4 peptide binding sites and a possible 'APP-secretase' activity associated with rat brain cortical membranes

    Allsop, D., Yamamoto, T., Kametani, F., Miyazaki, N. & Ishii, T., 14/06/1991, In: Brain Research. 551, 1-2, p. 1-9 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

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