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Dr Edward Parkin

Senior Lecturer in Biomedicine

  1. Published

    Membrane raft actin deficiency and altered Ca2+-induced vesiculation in stomatin-deficient overhydrated hereditary stomatocytosis

    Wilkinson, D. K., Turner, E. J., Parkin, E. T., Garner, A. E., Harrison, P. J., Crawford, M., Stewart, G. W. & Hooper, N. M., 01/2008, In: Biochimica et Biophysica Acta (BBA) - Biomembranes. 1778, 1, p. 125-132 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  2. Published

    Glycosylation and glycosylphosphatidylinositol membrane anchors

    Turner, A., Parkin, E. & Hooper, N., 1996, Regulatory protein modification: techniques and protocols. Hemmings, H. C. (ed.). Humana Press, Vol. 30. p. 395-427 33 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  3. Published

    Development of a proteolytically stable retro-inverso peptide inhibitor of β-amyloid oligomerization as a potential novel treatment for Alzheimer's disease

    Taylor, M., Moore, S., Mayes, J., Parkin, E., Beeg, M., Canovi, M., Gobbi, M., Mann, D. M. A. & Allsop, D., 2010, In: Biochemistry. 49, 15, p. 3261-3272 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  4. Published

    Role of ADAMs in the ectodomain shedding and conformational conversion of the prion protein

    Taylor, D. R., Parkin, E. T., Cocklin, S. L., Ault, J. R., Ashcroft, A. E., Turner, A. J. & Hooper, N. M., 21/08/2009, In: Journal of Biological Chemistry. 284, 34, p. 22590-22600 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  5. Published

    The Amyloid Precursor Protein Plays Differential Roles in the UVA Resistance and Proliferation of Human Retinal Pigment Epithelial Cells

    Sultan, F. & Parkin, E., 30/03/2022, In: Protein and Peptide Letters. 29, 4, p. 313-327 15 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  6. Published

    Herpes simplex virus interferes with amyloid precursor protein processing.

    Shipley, S. J., Parkin, E. T., Itzhaki, R. F. & Dobson, C. B., 18/08/2005, In: BMC Microbiology. 5, p. 48

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  7. Published

    Ectodomain shedding of the Notch ligand Jagged1 is mediated by ADAM17, but is not a lipid-raft-associated event

    Parr-Sturgess, C. A., Rushton, D. J. & Parkin, E. T., 2010, In: Biochemical Journal. 432, 2, p. 283-294 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  8. Published

    Copper modulates zinc metalloproteinase-dependent ectodomain shedding of key signalling and adhesion proteins and promotes the invasion of prostate cancer epithelial cells

    Parr-Sturgess, C. A., Tinker, C. L., Hart, C. A., Brown, M. D., Clarke, N. W. & Parkin, E. T., 10/2012, In: Molecular Cancer Research. 10, 10, p. 1282-1293 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  9. Published

    Cellular pion protein regulates beta-secretase cleavage of the Alzheimers amyloid precurs protein.

    Parkin, E., Watt, N. T., Hussain, I., Eckman, E. A., Eckman, C. B., Manson, J. C., Baybutt, H. N., Turner, A. J. & Hooper, N. M., 26/06/2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 26, p. 11062-11067 6 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  10. Published

    Dual Mechanisms for Shedding of the Cellular Prion Protein.

    Parkin, E. T., Watt, N. T., Turner, A. J. & Hooper, N. M., 19/03/2004, In: Journal of Biological Chemistry. 279, 12, p. 11170-11178 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  11. Published

    The ectodomain shedding of angiotensin-converting enzyme is independent of its localisation in lipid rafts.

    Parkin, E. T., Tan, F., Skidgel, R. A., Turner, A. J. & Hooper, N. M., 1/08/2003, In: Journal of Cell Science. 116, 15, p. 3079-3087 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  12. Published

    Structure-Activity Relationship of Hydroxamate-Based Inhibitors on the Secretases that Cleave the Amyloid Precursor Protein, Angiotensin Converting Enzyme, CD23, and Pro-Tumor Necrosis Factor.

    Parkin, E. T., Trew, A., Christie, G., Faller, A., Mayer, R., Turner, A. J. & Hooper, N. M., 16/04/2002, In: Biochemistry. 41, 15, p. 4972-4981 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  13. Published

    Differential effects of glycosphingolipids on the detergent-insolubility of the glycosylphosphatidylinositol-anchored membrane dipeptidase.

    Parkin, E. T., Turner, A. J. & Hooper, N. M., 15/08/2001, In: Biochemical Journal. 358, 1, p. 209-216 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  14. Published

    Amyloid precursor protein, although partially detergent-insoluble in mouse cerebral cortex, behaves as an atypical lipid raft protein.

    Parkin, E. T., Turner, A. J. & Hooper, N. M., 15/11/1999, In: Biochemical Journal. 344, 1, p. 23-30 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  15. Published

    Characterization of Detergent-Insoluble Complexes Containing the Familial Alzheimer's Disease-Associated Presenilins.

    Parkin, E. T., Hussain, I., Karran, E. H., Turner, A. J. & Hooper, N. M., 04/1999, In: Journal of Neurochemistry. 72, 4, p. 1534-1543 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  16. Published

    Modulation of phosphatidylcholine biosynthesis in celery by exogenous fatty acids.

    Parkin, E. T. & Rolphe, C. E., 15/01/1999, In: Phytochemistry. 50, 1, p. 47-51 5 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  17. Published

    Secretase-mediated cell surface shedding of the angiotensin-converting enzyme.

    Parkin, E. T., Turner, A. J. & Hooper, N. M., 2004, In: Protein and Peptide Letters. 11, p. 423-432 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  18. Published

    Distribution of presenilins and amyloid precursor protein in detergent-insoluble membrane domains.

    Parkin, E. T., Turner, A. J. & Hooper, N. M., 1999, Alzheimer's disease : methods and protocols. Walker, J. M. (ed.). Humana Press, p. 345-360 16 p.

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNChapter

  19. Published

    The Alzheimer's amyloid precursor protein a-secretase and the angiotensin converting enzyme secretase exhibit closely related enzyme activities.

    Parkin, E. T., Turner, A. J. & Hooper, N. M., 2000.

    Research output: Contribution to conference - Without ISBN/ISSN Other

  20. Published

    Caveolae-like membranes and the amyloid precursor protein : a critical reassessment.

    Parkin, E. T., Turner, A. J. & Hooper, N. M., 1999, In: British Neuroscience Association Abstracts. 15, p. 59

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  21. Published

    Caveolae-like membranes and the amyloid precursor protein : a critical reassessment.

    Parkin, E. T., Turner, A. J. & Hooper, N. M., 06/1999, In: Journal of Neurochemistry. 72, Supple, p. S71

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  22. Published

    A disintegrin and metalloproteinase (ADAM)-mediated ectodomain shedding of ADAM10

    Parkin, E. & Harris, B., 03/2009, In: Journal of Neurochemistry. 108, 6, p. 1464-1479 16 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  23. Published

    Phoshatidylcholine biosynthesis and cell growth in Apium graveolens

    Parkin, E. & Rolph, C., 08/1995, In: Physiologia Plantarum. 94, 4, p. 643-650 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  24. Published

    Isolation and characterization of two distinct low-density, Triton-insoluble, complexes from porcine lung membranes

    Parkin, E., Turner, A. J. & Hooper, N. M., 1996, In: Biochemical Journal. 319 , 3, p. 887-896 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  25. Published

    The amyloid precursor protein is not enriched in caveolae-like, detergent-insoluble membrane microdomains

    Parkin, E., Hussain, I., Turner, A. J. & Hooper, N. M., 11/1997, In: Journal of Neurochemistry. 69, 5, p. 2179-2188 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

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