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Research

Professor John Whitehead

Emeritus

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  1. 2010
  2. Published

    A combined score test for binary and ordinal endpoints from clinical trials.

    Whitehead, J., Branson, M. & Todd, S., 28/02/2010, In: Statistics in Medicine. 29, 5, p. 521-532 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. 2009
  4. Published

    Action following the discovery of a global association between the whole genome and adverse event risk in a clinical drug-development programme.

    Whitehead, J., Kelly, P., Zhou, Y., Stallard, N., Thygesen, H. & Bowman, C., 10/2009, In: Pharmaceutical Statistics. 8, 4, p. 287-300 14 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  5. Published

    A simple two-stage design for quantitative responses with appliction to a study in diabectic neuropathic pain.

    Whitehead, J., Valdés-Márquez, E. & Lissmats, A., 04/2009, In: Pharmaceutical Statistics. 8, 2, p. 125-135 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  6. Published

    Evaluation of a sequential global test of improved recovery following stroke as applied to the ICTUS trial of citicoline.

    Bolland, K., Whitehead, J., Cobo, E. & Secades, J. J., 04/2009, In: Pharmaceutical Statistics. 8, 2, p. 136-149 14 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  7. Published

    Using historical lesion volume data in the design of a new phase II clinical trial in acute stroke.

    Whitehead, J., Bolland, K., Valdés-Márquez, E., Lihic, A., Ali, M. & Lees, K., 04/2009, In: Stroke. 40, 4, p. 1347-1352 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  8. Published

    One- and two-stage design proposals for a phase II trial comparing three active treatments with control using an ordered categorical endpoint.

    Whitehead, J. & Jaki, T., 28/02/2009, In: Statistics in Medicine. 28, 5, p. 828-847 20 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  9. 2008
  10. Published

    Fitting models for the joint action of two drugs using SAS(R).

    Whitehead, A., Whitehead, J., Todd, S., Zhou, Y. & Smith, M. K., 10/2008, In: Pharmaceutical Statistics. 7, 4, p. 272-284 13 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  11. Published

    Estimation following selection of the largest of two normal means. Journal of Statistical Planning and Inference 138, 1629-1638.

    Stallard, N., Todd, S. & Whitehead, J., 1/07/2008, In: Journal of Statistical Planning and Inference. 138, 6, p. 1629-1638 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  12. Published

    A safety monitoring procesure for a clinical drug development programme, with application to the accessment of a novel COX-2 inhibitor.

    Bolland, K., Whitehead, J. & Oldham, M., 07/2008, In: Journal of Biopharmaceutical Statistics. 18, 4, p. 737-749 13 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  13. Published

    Bayesian sample size for exploratory clinical trials incorporating historical data.

    Whitehead, J., Valdés-Márquez, E., Johnson, P. & Graham, G., 06/2008, In: Statistics in Medicine. 27, 13, p. 2307-2327 21 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  14. Published

    Sequentially testing for a gene-drug interaction in a genomewide analysis.

    Kelly, P., Zhou, Y., Whitehead, J., Stallard, N. & Bowman, C., 20/05/2008, In: Statistics in Medicine. 27, 11, p. 2022-2034 13 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  15. Published

    Incorporating intermediate binary responses into interim analyses of clinical trials : a comparison of four methods.

    Whitehead, A., Sooriyarachchi, M. R., Whitehead, J. & Bolland, K., 10/05/2008, In: Statistics in Medicine. 27, 10, p. 1646-1666 21 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  16. Published

    Implementation of a Bayesian design in a dose-escalation study of an experimental agent in healthy volunteers.

    Whitehead, J., Korhonen, P., Mustonen, M. & Zhou, Y., 03/2008, In: Biometrics. 64, 1, p. 299-308 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  17. 2007
  18. Published

    A Bayesian approach for dose-escalation in a phase I clinical trial incorporating pharmacodynamic endpoints .

    Whitehead, J., Hampson, L., Zhou, Y., Ledent, E. & Pereira, A., 11/2007, In: Journal of Biopharmaceutical Statistics. 17, 6, p. 1117-1129 13 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  19. 2006
  20. Published

    Sequential genome-wide association studies for monitoring adverse events in clinical evaluation of new drugs.

    Whitehead, J., Kelly, P. J., Stallard, N., Zhou, Y. & Bowman, C., 30/09/2006, In: Statistics in Medicine. 25, 18, p. 3081-3092 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  21. Published

    The sequential analysis of repeated binary responses: a score test for the case of three time points.

    Sooriyarachchi, M. R., Whitehead, J., Whitehead, A. & Bolland, K., 15/07/2006, In: Statistics in Medicine. 25, 13, p. 2196-2214 19 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  22. 2003
  23. Published

    Incorporating data received after a sequential trial has stopped into the final analysis: implementation and comparison of methods.

    Whitehead, J., Bollard, K., Matsushita, T., Sooriyarachchi, M. R. & Whitehead, A., 09/2003, In: Biometrics. 59, 3, p. 701-709 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  24. 2001
  25. Published

    Easy-to-implement Bayesian methods for dose-escalation studies in healthy volunteers.

    Whitehead, J., Patterson, S., Webber, D. & Zhou, Y., 03/2001, In: Biostatistics. 2, 1, p. 47-61 15 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  26. 1991
  27. Published

    Analysis of failure time data with ordinal categories of response

    Berridge, D. & Whitehead, J., 11/1991, In: Statistics in Medicine. 10, 11, p. 1703-1710 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  28. Published

    Mammographic dysplasia as entry criterion for breast cancer prevention trials

    Berridge, D., Whitehead, J. & Cuzick, J., 18/05/1991, In: The Lancet. 337, 8751, p. 1225 1 p.

    Research output: Contribution to Journal/Magazine › Letter › peer-review

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