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Professor Thomas Jaki

Formerly at Lancaster University

  1. Published

    Tilting the lasso by knowledge-based post-processing

    Tharmaratnam, K., Sperrin, M., Jaki, T. F., Reppe, S. & Frigessi, A., 2/09/2016, In: BMC Bioinformatics. 17, 9 p., 344.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  2. Published

    Recurrent events modelling of haemophilia bleeding events

    Titman, A., Wolfsegger, M. J. & Jaki, T., 1/03/2021, In: Journal of the Royal Statistical Society: Series C (Applied Statistics). 70, 2, p. 351-371 21 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  3. Published

    Using Multilevel Mixtures to Evaluate Intervention Effects in Group Randomized Trials.

    Van Horn, M. L., Fagan, A. A., Jaki, T., Brown, E. C., Hawkins, J. D., Arthur, M. W., Abbott, R. D. & Catalano, R. F., 04/2008, In: Multivariate Behavioral Research. 43, 2, p. 289-326 38 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  4. Published

    Assessing differential effects: Applying regression mixture models to identify variations in the influence of family resources on academic achievement.

    Van Horn, M. L., Jaki, T., Maysn, K., Ramey, S. L., Smith, J. A. & Antaramian, S., 09/2009, In: Developmental Psychology. 45, 5, p. 1298-1313 16 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  5. Published

    Not quite normal: Consequences of violating the assumption of normality with regression mixture models

    Van Horn, M. L., Smith, J., Fagan, A., Jaki, T., Maysn, K., Hawkins, D., Feaster, D. & Howe, G., 2012, In: Structural Equation Modeling. 19, 2, p. 227-249 23 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  6. Published

    Evaluating differential effects using regression interactions and regression mixture models

    Van Horn, M. L., Jaki, T., Maysn, K., Howe, G., Feaster, D., Lamont, A. E., George, M. & Kim, M., 08/2015, In: Educational and Psychological Measurement. 75, 4, p. 677-714 38 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  7. Published

    Using multilevel regression mixture models to identify level-1 heterogeneity in level-2 effects

    Van Horn, M. L., Feng, Y., Kim, M., Lamont, A. E., Feaster, D. & Jaki, T., 2016, In: Structural Equation Modeling. 23, 2, p. 259-269 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  8. Published

    A Bayesian model to estimate the cutoff and the clinical utility of a biomarker assay

    Vradi, E., Jaki, T. F., Vonk, R. & Brannath, W., 1/08/2019, In: Statistical Methods in Medical Research. 28, 8, p. 2538-2556 19 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  9. Published

    Model selection based on combined penalties for biomarker identification

    Vradi, E., Brannath, W., Jaki, T. & Vonk, R., 4/07/2018, In: Journal of Biopharmaceutical Statistics. 28, 4, p. 735-749 15 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  10. Published

    Extrapolation of efficacy and other data to support the development of new medicines for children: a systematic review of methods

    Wadsworth, I., Hampson, L. V. & Jaki, T. F., 1/02/2018, In: Statistical Methods in Medical Research. 27, 2, p. 398-413 16 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  11. Published

    Clinical drug development in epilepsy revisited: a proposal for a new paradigm streamlined using extrapolation

    Wadsworth, I., Jaki, T. F., Sills, G. J., Appleton, R., Cross, J. H., Marson, A. G., Martland, T., McLellan, A., Smith, P. E. M., Pellock, J. M. & Hampson, L. V., 11/2016, In: CNS Drugs. 30, 11, p. 1011-1017 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  12. Published

    A quantitative framework to inform extrapolation decisions in children

    Wadsworth, I., Hampson, L. V., Jaki, T., Sills, G. J., Marson, A. G. & Appleton, R., 1/02/2020, In: Journal of the Royal Statistical Society: Series A Statistics in Society. 183, 2, p. 515-534 20 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  13. Published

    Exposure–response modelling approaches for determining optimal dosing rules in children

    Wadsworth, I., Hampson, L. V., Bornkamp, B. & Jaki, T., 1/09/2020, In: Statistical Methods in Medical Research. 29, 9, p. 2583-2602 20 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  14. Published

    Confidence regions for treatment effects in subgroups in biomarker stratified designs

    Wan, F., Kunz, C. U. & Jaki, T. F., 1/01/2019, In: Biometrical Journal. 61, 1, p. 27-39 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  15. Published

    Subgroup analysis of treatment effects for misclassified biomarkers with time-to-event data

    Wan, F., Titman, A. & Jaki, T., 1/11/2019, In: Journal of the Royal Statistical Society: Series C (Applied Statistics). 68, 5, p. 1447-1463 17 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  16. Published

    Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial

    Wang, Y., Zhang, D., Du, G., Du, R., Zhao, J., Jin, Y., Fu, S., Gao, L., Cheng, Z., Lu, Q., Hu, Y., Luo, G., Wang, K., Lu, Y., Li, H., Wang, S., Ruan, S., Yang, C., Mei, C., Ding, D., & 25 othersWu, F., Tang, X., Ye, X., Ye, Y., Liu, B., Yang, J., Yin, W., Wang, A., Fan, G., Zhou, F., Liu, Z., Gu, X., Xu, J., Shang, L., Zhang, Y., Cao, L., Guo, T., Wan, Y., Qin, H., Jiang, Y., Jaki, T., Hayden, F. G., Horby, P. W., Cao, B. & Wang, C., 16/05/2020, In: The Lancet. p. 1569-1578 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  17. Published

    Evaluation of the efficacy and safety of intravenous remdesivir in adult patients with severe COVID-19: Study protocol for a phase 3 randomized, double-blind, placebo-controlled, multicentre trial

    Wang, Y., Zhou, F., Zhang, D., Zhao, J., Du, R., Hu, Y., Cheng, Z., Gao, L., Jin, Y., Luo, G., Fu, S., Lu, Q., Du, G., Wang, K., Lu, Y., Fan, G., Zhang, Y., Liu, Y., Ruan, S., Liu, W., & 5 othersJaki, T., Hayden, F. G., Horby, P. W., Cao, B. & Wang, C., 24/05/2020, In: Trials. 21, 1, 11 p., 422.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  18. Published

    Optimal design of multi-arm multi-stage trials

    Wason, J. & Jaki, T., 30/12/2012, In: Statistics in Medicine. 31, 30, p. 4269-4279 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  19. Published

    Some recommendations for multi-arm multi-stage trials

    Wason, J., Magirr, D., Law, M. & Jaki, T., 04/2016, In: Statistical Methods in Medical Research. 25, 2, p. 716-727 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  20. Published

    Planning multi-arm screening studies within the context of a drug development programme

    Wason, J., Jaki, T. & Stallard, N., 10/09/2013, In: Statistics in Medicine. 32, 20, p. 3424-3435 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  21. Published

    A review of statistical designs for improving the efficiency of phase II studies in oncology

    Wason, J. & Jaki, T., 06/2016, In: Statistical Methods in Medical Research. 25, 3, p. 1010-1021 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  22. Published

    Practical guidance for planning resources required to support publicly-funded adaptive clinical trials

    Wason, J. M. S., Dimairo, M., Biggs, K., Bowden, S., Brown, J., Flight, L., Hall, J., Jaki, T., Lowe, R., Pallmann, P., Pilling, M. A., Snowdon, C., Sydes, M. R., Villar, S. S., Weir, C. J., Wilson, N., Yap, C., Hancock, H. & Maier, R., 10/08/2022, In: BMC Medicine. 20, 1, 12 p., 254.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  23. Published

    How to design a dose-finding study using the continual reassessment method

    Wheeler, G. M., Mander, A. P., Bedding, A., Brock, K., Cornelius, V., Grieve, A. P., Jaki, T., Love, S. B., Odondi, L., Weir, C. J., Yap, C. & Bond, S. J., 18/01/2019, In: BMC Medical Research Methodology. 19, 1, 15 p., 18.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  24. Published

    One- and two-stage design proposals for a phase II trial comparing three active treatments with control using an ordered categorical endpoint.

    Whitehead, J. & Jaki, T., 28/02/2009, In: Statistics in Medicine. 28, 5, p. 828-847 20 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  25. Published

    A novel phase I/IIa design for early phase oncology studies and its application in the evaluation of MK-0752 in pancreatic cancer

    Whitehead, J., Thygesen, H., Jaki, T., Davis, S., Halford, S., Turner, H., Cook, N. & Jodrell, D., 15/08/2012, In: Statistics in Medicine. 31, 18, p. 1931-1943 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

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