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Dr Timothy Douglas

Lecturer in Bio-Chemical Engineering

  1. Published

    The influence of Ca/Mg ratio on autogelation of hydrogel biomaterials with bioceramic compounds

    Abalymov, A., Lengert, E., Van der Meeren, L., Saveleva, M., Ivanova, A., Douglas, T., Douglas, E. L., Skirtach, A. G., Volodkin, D. & Parakhonskiy, B. V., 28/02/2022, In: Materials Science and Engineering: C . 133, 10 p., 112632.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  2. Published

    Dehydration analysis of poly-ethylene glycol hydrogels with terahertz imaging

    Baines, D., Bassu, G., Wright, K., Douglas, T., Degl'Innocenti, R., Laurati, M. & Lin, H., 3/08/2023, Technical Digest Series: Optica Sensing Congress 2023 (AIS, FTS, HISE, Sensors, ES). Optica Publishing Group, paper JW2A.3

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paperpeer-review

  3. Published

    The enrichment of whey protein isolate hydrogels with Poly-γ-glutamic acid promotes the proliferation and osteogenic differentiation of pre-osteoblasts

    Baines, D., Platania, V., Tavernaraki, N., Parati, M., Wright, K., Radecka, I., Chatzinikolaidou, M. & Douglas, T., 23/12/2023, In: Gels. 10, 1, 18.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  4. Published

    The Enrichment of Whey Protein Isolate Hydrogels with Poly-γ-Glutamic Acid Promotes the Proliferation and Osteogenic Differentiation of Preosteoblasts

    Baines, D. K., Platania, V., Tavernaraki, N. N., Parati, M., Wright, K., Radecka, I., Chatzinikolaidou, M. & Douglas, T. E. L., 23/12/2023, In: Gels. 10, 1, p. 18

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  5. Published

    Whey protein complexes with green tea polyphenols: antimicrobial, osteoblast-stimulatory and antioxidant activities

    Carson, M., Keppler, J. K., Brackman, G., Dawood, D., Vandrovcová, M., El-Sayed, K. F., Coenye, T., Clarke, S., Skirtach, A. G. & Douglas, T. E. L., 1/05/2019, In: cells tissues organs. 206, 1-2, p. 106-117 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  6. Published

    Functionalization of additive-manufactured Ti6Al4V scaffolds with poly(allylamine hydrochloride)/poly(styrene sulfonate) bilayer microcapsule system containing dexamethasone

    Chudinova, E., Koptyug, A., Mukhortova, Y., Pryadko, A., Volkova, A., Ivanov, A., Plotnikov, E., Khan, Y., Epple, M., Sokolova, V., Prymak, O., Douglas, T., Surmenev, R. & Surmeneva, M., 15/11/2021, In: Materials Chemistry and Physics. 273, 14 p., 125099.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  7. Published

    Biosurfactants as foaming agents in calcium phosphate bone cements

    Cichon, E., Czechowska, J., Krok-Borkowicz, M., Allinson, S., Stepien, K., Smith, A., Pamula, E., Douglas, T. & Zima, A., 28/02/2023, In: Biomaterials Advances. 145, 14 p., 213273.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  8. Published

    Ulvan-chitosan polyelectrolyte complexes as matrices for enzyme induced biomimetic mineralization

    Dash, M., Samal, S. K., Morelli, A., Bartoli, C., Declercq, H. A., Douglas, T. E. L., Dubruel, P. & Chiellini, F., 15/02/2018, In: Carbohydrate Polymers. 182, p. 254-264 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  9. Published

    Enzymatically biomineralized chitosan scaffolds for tissue-engineering applications

    Dash, M., Samal, S. K., Douglas, T. E. L., Schaubroeck, D., Leeuwenburgh, S. C., Voort, P. V. D., Declercq, H. A. & Dubruel, P., 1/05/2017, In: Journal of Tissue Engineering and Regenerative Medicine. 11, 5, p. 1500-1513 14 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  10. Published

    Application of whey protein isolate in bone regeneration: Effects on growth and osteogenic differentiation of bone-forming cells

    Douglas, T. E. L., Vandrovcová, M., Kročilová, N., Keppler, J. K., Zárubová, J., Skirtach, A. G. & Bačáková, L., 01/2018, In: Journal of Dairy Science. 101, 1, p. 28-36 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  11. Published

    Novel self-gelling injectable hydrogel/alpha-tricalcium phosphate composites for bone regeneration: Physiochemical and microcomputer tomographical characterization

    Douglas, T. E. L., Schietse, J., Zima, A., Gorodzha, S., Parakhonskiy, B., Khalenkow, D., Shkarin, R., Ivanova, A., Baumbach, T., Weinhardt, V., Stevens, C., Vanhoorne, V., Vervaet, C., Balcaen, L., Vanhaecke, F., Slosarczyk, A., Surmeneva, M., Surmenev, R. & Skirtach, A., 03/2018, In: Journal of Biomedical Materials Research Part A. 106, 3, p. 822-828 7 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  12. Published

    Ca:Mg:Zn:CO3 and Ca:Mg:CO3-tri- and bi-elemental carbonate microparticles for novel injectable self-gelling hydrogel-microparticle composites for tissue regeneration

    Douglas, T. E. L., Sobczyk, K., Łapa, A., Włodarczyk, K., Brackman, G., Vidiasheva, I., Reczyńska, K., Pietryga, K., Schaubroeck, D., Bliznuk, V., Van Der Voort, P., Declercq, H., Van den Bulcke, J., Samal, S. K., Khalenkow, D., Parakhonskiy, B., Van Acker, J., Coenye, T., Lewandowska-Szumieł, M., Pamuła, E., & 1 othersSkirtach, A., 24/03/2017, In: Biomedical Materials. 12, 2, 13 p., 025015.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  13. Published

    Novel injectable gellan gum hydrogel composites incorporating Zn- and Sr-enriched bioactive glass microparticles: high-resolution X-Ray micro-computed tomography, antibacterial and in vitro testing

    Douglas, T. E. L., Dziadek, M., Gorodzha, S., Liskova, J., Brackman, G., Vanhoorne, V., Vervaet, C., Balcaen, L., del Rosario Florez Garcia, M., Boccaccini, A., Weinhardt, V., Baumbach, T., Vanhaecke, F., Coenye, T., Bacakova, L., Surmeneva, M., Surmenev, R., Cholewa-Kowalska, K. & Skirtach, A., 06/2018, In: Journal of Tissue Engineering and Regenerative Medicine. 12, 6, p. 1313-1326 14 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  14. Published

    Pectin coatings on titanium alloy scaffolds produced by additive manufacturing: Promotion of human bone marrow stromal cell proliferation

    Douglas, T. E. L., Hempel, U., Zydek, J., Vladescu, A., Pietryga, K., Kaeswurm, J., Buchweitz, M., Surmenev, R., Surmeneva, M., Cotrut, C., Koptyug, A. & Pamula, E., 15/09/2018, In: Materials Letters. 227, p. 225-228 4 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  15. Published

    Generation of composites for bone tissue-engineering applications consisting of gellan gum hydrogels mineralized with calcium and magnesium phosphate phases by enzymatic means

    Douglas, T. E. L., Krawczyk, G., Pamula, E., Declercq, H., Schaubroeck, D., Bucko, M., Balcaen, L., Van der Voort, P., Bliznuk, V., van den Vreken, N., Dash, M., Detsch, R., Boccaccini, A., Vanhaecke, F., Cornelissen, R. & Dubruel, 11/2016, In: Journal of Tissue Engineering and Regenerative Medicine. 10, 11, p. 938-954 17 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  16. Published

    Composites of gellan gum hydrogel enzymatically mineralized with calcium-zinc phosphate for bone regeneration with antibacterial activity.

    Douglas, T. E. L., Pilarz, M., Lopez-Heredia, M., Brackman, G., Schaubroeck, D., Balcaen, L., Bliznuk, V., Dubruel, P., Knabe-Ducheyne, Vanhaecke, F., Coenye, T. & Pamula, E., 05/2017, In: Journal of Tissue Engineering and Regenerative Medicine. 11, 5, p. 1610-1618 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  17. Published

    Enzymatic, urease-mediated mineralization of gellan gum hydrogel with calcium carbonate, magnesium-enriched calcium carbonate and magnesium carbonate for bone regeneration applications.

    Douglas, T. E. L., Lapa, A., Samal, S., Declercq, H., Declercq, H., Schaubroeck, D., Mendes, A., Van der Voort, P., Dokupil, A., Plis, A., De Schamphelaere, K., Chronakis, I., Pamula, E. & Skirtach, A., 12/2017, In: Journal of Tissue Engineering and Regenerative Medicine. p. 3556-3566 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  18. Published

    Enzymatic mineralization of gellan gum hydrogel for bone tissue-engineering applications and its enhancement by polydopamine

    Douglas, T. E. L., Wlodarczyk, M., Pamula, E., Declercq, H., de Mulder, E., Bucko, M., Balcaen, L., Vanhaecke, F., Cornelissen, R., Dubruel, P., Jansen, J. & Leeuwenburgh, S., 1/11/2014, In: Journal of Tissue Engineering and Regenerative Medicine. 8, 11, p. 906-918 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  19. Published

    Enzymatic Mineralization of Hydrogels for Bone Tissue Engineering by Incorporation of Alkaline Phosphatase

    Douglas, T. E. L., Messersmith, P. B., Chasan, S., Mikos, A. G., de Mulder, E. L. W., Dickson, G., Schaubroeck, D., Balcaen, L., Vanhaecke, F., Dubruel, P., Jansen, J. A. & Leeuwenburgh, S. C. G., 08/2012, In: Macromolecular Bioscience. 12, 8, p. 1077-1089 13 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  20. Published

    Pectin-bioactive glass self-gelling, injectable composites with high antibacterial activity

    Douglas, T. E. L., Dziadek, M., Schietse, J., Boone, M., Declercq, H., Coenye, T., Vanhoorne, V., Vervaet, C., Balcaen, L., Buchweitz, M., Vanhaecke, F., Van Assche, F., Cholewa-Kowalska, K. & Skirtach, A. G., 1/02/2019, In: Carbohydrate Polymers. 205, p. 427-436 10 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  21. Published

    Titanium surface functionalization with coatings of chitosan and polyphenol-rich plant extracts

    Douglas, T. E. L., Kumari, S., Dziadek, K., Dziadek, M., Abalymov, A., Cools, P., Brackman, G., Coenye, T., Morent, R., Mohan, M. K. & Skirtach, A. G., 1/06/2017, In: Materials Letters. 196, p. 213-216 4 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  22. Published

    Enrichment of enzymatically mineralized gellan gum hydrogels with phlorotannin-rich Ecklonia cava extract Seanol(®) to endow antibacterial properties and promote mineralization

    Douglas, T. E. L., Dokupil, A., Reczyńska, K., Brackman, G., Krok-Borkowicz, M., Keppler, J. K., Božič, M., Van Der Voort, P., Pietryga, K., Samal, S. K., Balcaen, L., van den Bulcke, J., Van Acker, J., Vanhaecke, F., Schwarz, K., Coenye, T. & Pamuła, E., 10/08/2016, In: Biomedical Materials. 11, 4, 13 p., 045015.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  23. Published

    Acceleration of gelation and promotion of mineralization of chitosan hydrogels by alkaline phosphatase

    Douglas, T. E. L., Skwarczynska, A., Modrzejewska, Z., Balcaen, L., Schaubroeck, D., Lycke, S., Vanhaecke, F., Vandenabeele, P., Dubruel, P., Jansen, J. A. & Leeuwenburgh, S. C. G., 05/2013, In: International Journal of Biological Macromolecules. 56, p. 122-132 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  24. Published

    Enrichment of chitosan hydrogels with perfluorodecalin promotes gelation and stem cell vitality

    Douglas, T. E. L., Pilarek, M., Kalaszczynska, I., Senderek, I., Skwarczynska, A., Cuijpers, V. M. J. I., Modrzejewska, Z., Lewandowska-Szumiel, M. & Dubruel, P., 1/08/2014, In: Materials Letters. 128, p. 79-84 6 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  25. Published

    Phenolic plant extract enrichment of enzymatically mineralized hydrogels

    Douglas, T., Lopez-Heredia, M., Pulczynska, A., Łapa, A., Pietryga, K., Schaubroeck, D., Santos, S., Pais, A., Brackman, G., De Schamphelaere, K., Samal, S. K., Keppler, J. K., Bauer, J., Chai, F., Blanchemain, N., Coenye, T., Pamula, E. & Skirtach, A. G., 1/10/2019, In: Engineering of Biomaterials (Inzyneria Biomaterialow). 22, 149, p. 2-9 8 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

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