Using multiple genetic variants as instrumental variables for modifiable risk factors

Palmer, T. M., Lawlor, D. A., Harbord, R. M., Sheehan, N. A., Tobias, J. H., Timpson, N. J., Davey Smith, G. & Sterne, J. A. C., 06/2012, In: Statistical Methods in Medical Research. 21, 3, p. 223-242 20 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Using genetics to test the causal relationship of total adiposity and periodontitis: Mendelian randomization analyses in the Gene-Lifestyle Interactions and Dental Endpoints (GLIDE) Consortium

Shungin, D., Cornelis, M. C., Divaris, K., Holtfreter, B., Shaffer, J. R., Yu, Y-H., Barros, S. P., Beck, J. D., Biffar, R., Boerwinkle, E. A., Crout, R. J., Ganna, A., Hallmans, G., Hindy, G., Hu, F. B., Kraft, P., McNeil, D. W., Melander, O., Moss, K. L., North, K. E., & 21 othersOrho-Melander, M., Pedersen, N. L., Ridker, P. M., Rimm, E. B., Rose, L. M., Rukh, G., Teumer, A., Weyant, R. J., Chasman, D. I., Joshipura, K., Kocher, T., Magnusson, P. K. E., Marazita, M. L., Nilsson, P., Offenbacher, S., Davey Smith, G., Lundberg, P., Palmer, T. M., Timpson, N. J., Johansson, I. & Franks, P. W., 2015, In: International Journal of Epidemiology. 44, 2, p. 638-650 13 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Using genetic variation to explore the causal effect of maternal pregnancy adiposity on future offspring adiposity: a Mendelian randomisation study

Richmond, R., Timpson, N. J., Felix, J., Palmer, T. M., Gaillard, R., McMahon, G., Davey Smith, G., Jaddoe, V. & Lawlor, D. A., 24/01/2017, In: PLoS Medicine. 14, 1, 24 p., e1002221.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Using genetic loci to understand the relationship between adiposity and psychological distress: a Mendelian Randomization study in the Copenhagen General Population Study of 53,221 adults

Lawlor, D. A., Harbord, R. M., Tybjaerg-Hansen, A., Palmer, T. M., Zacho, J., Benn, M., Timpson, N. J., Smith, G. D. & Nordestgaard, B. G., 05/2011, In: Journal of Internal Medicine. 269, 5, p. 525-537 13 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

UK Families with Children with Rare Chromosome Disorders: Changing Experiences of Diagnosis and Counseling (2003 to 2013)

Szczepura, A., Wynn, S., Searle, B., Khan, A., Palmer, T. M., Biggerstaff, D., Elliott, J. & Hulten, M., 05/2018, In: Clinical Genetics. 93, 5, p. 972-981 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

To Adjust or Not to Adjust? When a "Confounder" Is Only Measured After Exposure

Groenwold, R. H. H., Palmer, T. M. & Tilling, K., 31/03/2021, In: Epidemiology. 32, 2, p. 194-201 8 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

The effect of elevated body mass index on ischemic heart disease risk: causal estimates from a Mendelian randomisation approach

Nordestgaard, B. G., Palmer, T. M., Benn, M., Zacho, J., Tybjaerg-Hansen, A., Davey Smith, G. & Timpson, N. J., 1/05/2012, In: PLoS Medicine. 9, 5, 13 p., e1001212.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

The causal roles of vitamin B(12) and transcobalamin in prostate cancer: can Mendelian randomization analysis provide definitive answers?

Collin, S. M., Metcalfe, C., Palmer, T. M., Refsum, H., Lewis, S. J., Smith, G. D., Cox, A., Davis, M., Marsden, G., Johnston, C., Lane, J. A., Donovan, J. L., Neal, D. E., Hamdy, F. C., Smith, A. D. & Martin, R. M., 2011, In: International Journal of Molecular Epidemiology and Genetics. 2, 4, p. 316-327 12 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Testing for non-linear causal effects using a binary genotype in a Mendelian randomization study: application to alcohol and cardiovascular traits

Silverwood, R. J., Holmes, M. V., Dale, C. E., Lawlor, D. A., Whittaker, J. C., Smith, G. D., Leon, D. A., Palmer, T., Keating, B. J., Zuccolo, L., Casas, J. P., Dudbridge, F. & Alcohol-ADH1B Consortium, 12/2014, In: International Journal of Epidemiology. 43, 6, p. 1781-1790 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Taller height as a risk factor for venous thromboembolism: a Mendelian randomization meta-analysis

Roetker, N., Armasu, S. M., Pankow, J. S., Lutsey, P. L., Tang, W., Rosenberg, M. A., Palmer, T. M., MacLehose, R. F., Heckbert, S. R., Cushman, M., de Andrade, M. & Folsom, A. R., 07/2017, In: Journal of Thrombosis and Haemostasis. 15, 7, p. 1334-1343 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Systematic review and metaanalysis of genetic association studies of urinary symptoms and prolapse in women

Cartwright, R., Kirby, A. C., Tikkinen, K. A. O., Mangera, A., Thiagamoorthy, G., Rajan, P., Pesonen, J., Ambrose, C., Gonzalez-Maffe, J., Bennett, P., Palmer, T., Walley, A., Järvelin, M-R., Chapple, C. & Khullar, V., 02/2015, In: American Journal of Obstetrics and Gynecology. 212, 2, p. 199.e1-24 24 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Systematic review and meta-analysis of candidate gene association studies of lower urinary tract symptoms in men

Cartwright, R., Mangera, A., Tikkinen, K. A. O., Rajan, P., Pesonen, J., Kirby, A. C., Thiagamoorthy, G., Ambrose, C., Gonzalez-Maffe, J., Bennett, P. R., Palmer, T., Walley, A., Järvelin, M-R., Khullar, V. & Chapple, C., 10/2014, In: European Urology. 66, 4, p. 752-768 17 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Software Application Profile: mrrobust - A Tool For Performing Two-Sample Summary Mendelian Randomization Analyses

Spiller, W., Davies, N. & Palmer, T. M., 12/09/2018, (E-pub ahead of print) In: International Journal of Epidemiology.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Software Application Profile: Bayesian estimation of inverse variance weighted and MR-Egger models for two-sample Mendelian randomization studies-mrbayes

Uche-Ikonne, O., Dondelinger, F. & Palmer, T., 28/02/2021, In: International Journal of Epidemiology. 50, 1, p. 43-49 7 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Smoking is associated with, but does not cause, depressed mood in pregnancy--a mendelian randomization study

Lewis, S. J., Araya, R., Smith, G. D., Freathy, R., Gunnell, D., Palmer, T. & Munafò, M., 07/2011, In: PLoS ONE. 6, 7, 5 p., e21689.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Severity of bias of a simple estimator of the causal odds ratio in Mendelian randomization studies

Harbord, R. M., Didelez, V., Palmer, T. M., Meng, S., Sterne, J. A. C. & Sheehan, N. A., 30/03/2013, In: Statistics in Medicine. 32, 7, p. 1246-1258 13 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study

Holmes, M. V., Simon, T., Exeter, H. J., Folkersen, L., Asselbergs, F. W., Guardiola, M., Cooper, J. A., Palmen, J., Hubacek, J. A., Carruthers, K. F., Horne, B. D., Brunisholz, K. D., Mega, J. L., van Iperen, E. P. A., Li, M., Leusink, M., Trompet, S., Verschuren, J. J. W., Hovingh, G. K., Dehghan, A., & 93 othersNelson, C. P., Kotti, S., Danchin, N., Scholz, M., Haase, C. L., Rothenbacher, D., Swerdlow, D. I., Kuchenbaecker, K. B., Staines-Urias, E., Goel, A., van 't Hooft, F., Gertow, K., de Faire, U., Panayiotou, A. G., Tremoli, E., Baldassarre, D., Veglia, F., Holdt, L. M., Beutner, F., Gansevoort, R. T., Navis, G. J., Mateo Leach, I., Breitling, L. P., Brenner, H., Thiery, J., Dallmeier, D., Franco-Cereceda, A., Boer, J. M. A., Stephens, J. W., Hofker, M. H., Tedgui, A., Hofman, A., Uitterlinden, A. G., Adamkova, V., Pitha, J., Onland-Moret, N. C., Cramer, M. J., Nathoe, H. M., Spiering, W., Klungel, O. H., Kumari, M., Whincup, P. H., Morrow, D. A., Braund, P. S., Hall, A. S., Olsson, A. G., Doevendans, P. A., Trip, M. D., Tobin, M. D., Hamsten, A., Watkins, H., Koenig, W., Nicolaides, A. N., Teupser, D., Day, I. N. M., Carlquist, J. F., Gaunt, T. R., Ford, I., Sattar, N., Tsimikas, S., Schwartz, G. G., Lawlor, D. A., Morris, R. W., Sandhu, M. S., Poledne, R., Maitland-van der Zee, A. H., Khaw, K-T., Keating, B. J., van der Harst, P., Price, J. F., Mehta, S. R., Yusuf, S., Witteman, J. C. M., Franco, O. H., Jukema, J. W., de Knijff, P., Tybjaerg-Hansen, A., Rader, D. J., Farrall, M., Samani, N. J., Kivimaki, M., Fox, K. A. A., Humphries, S. E., Anderson, J. L., Boekholdt, S. M., Palmer, T. M., Eriksson, P., Paré, G., Hingorani, A. D., Sabatine, M. S., Mallat, Z., Casas, J. P. & Talmud, P. J., 19/11/2013, In: Journal of the American College of Cardiology. 62, 21, p. 1966-1976 11 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Reading comprehension difficulties in children with rolandic epilepsy

Currie, N. K., Lew, A. R., Palmer, T. M., Basu, H., De Goede, C., Ayer, A. & Cain, K., 03/2018, In: Developmental Medicine and Child Neurology. 60, 3, p. 275-282 8 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Re: "credible mendelian randomization studies: approaches for evaluating the instrumental variable assumptions"

Palmer, T. M., Ramsahai, R. R., Lawlor, D. A., Sheehan, N. A. & Didelez, V., 1/09/2012, In: American Journal of Epidemiology. 176, 5, p. 457-458; author reply 458 2 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Prospective associations of parental smoking, alcohol use, marital status, maternal satisfaction, and parental and childhood body mass index at 6.5 years with later problematic eating attitudes

Wade, K. H., Skugarevsky, O., Kramer, M. S., Patel, S. R., Bogdanovich, N., Vilchuck, K., Sergeichick, N., Richmond, R., Palmer, T., Davey Smith, G., Gillman, M., Oken, E. & Martin, R. M., 2014, In: Nutrition and Diabetes. 4, 8 p., e100.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis

White, J., Sofat, R., Hemani, G., Shah, T., Engmann, J., Dale, C., Shah, S., Kruger, F. A., Giambartolomei, C., Swerdlow, D. I., Palmer, T., McLachlan, S., Langenberg, C., Zabaneh, D., Lovering, R., Cavadino, A., Jefferis, B., Finan, C., Wong, A., Amuzu, A., & 31 othersOng, K., Gaunt, T. R., Warren, H., Davies, T-L., Drenos, F., Cooper, J., Ebrahim, S., Lawlor, D. A., Talmud, P. J., Humphries, S. E., Power, C., Hypponen, E., Richards, M., Hardy, R., Kuh, D., Wareham, N., Ben-Shlomo, Y., Day, I. N., Whincup, P., Morris, R., Strachan, M. W. J., Price, J., Kumari, M., Kivimaki, M., Plagnol, V., Whittaker, J. C., Smith, G. D., Dudbridge, F., Casas, J. P., Holmes, M. V. & Hingorani, A. D., 04/2016, In: The Lancet Diabetes and Endocrinology. 4, 4, p. 327-336 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Older people with long term conditions using technologies supporting home based care: patterns of resource use, costs and health related quality of life

Mateus, C., Hernandez, A., Palmer, T., Varey, S. & Milligan, C., 10/2018, In: Value in Health. 21, Suppl. 3, p. S220-S220 1 p.

Research output: Contribution to Journal/Magazine › Meeting abstract › peer-review

Novel methods to deal with publication biases: secondary analysis of antidepressant trials in the FDA trial registry database and related journal publications

Moreno, S. G., Sutton, A. J., Turner, E. H., Abrams, K. R., Cooper, N. J., Palmer, T. M. & Ades, A. E., 2009, In: BMJ. 339, 7 p., b2981.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Nonparametric bounds for the causal effect in a binary instrumental variable model

Palmer, T. M., Ramsahai, R., Didelez, V. & Sheehan, N. A., 2011, In: Stata Journal. 11, 3, p. 345-367 23 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Multivariate multilevel spline models for parallel growth processes: application to weight and mean arterial pressure in pregnancy

Macdonald-Wallis, C., Lawlor, D. A., Palmer, T. & Tilling, K., 20/11/2012, In: Statistics in Medicine. 31, 26, p. 3147-3164 18 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review