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Analysis of patchclamp recordings: model-free multiscale methods and software

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Analysis of patchclamp recordings: model-free multiscale methods and software. / Pein, Florian; Eltzner, Benjamin; Munk, Axel.
In: European Biophysics Journal, Vol. 50, No. 2, 09.03.2021, p. 187-209.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Pein, F, Eltzner, B & Munk, A 2021, 'Analysis of patchclamp recordings: model-free multiscale methods and software', European Biophysics Journal, vol. 50, no. 2, pp. 187-209. https://doi.org/10.1007/s00249-021-01506-8

APA

Pein, F., Eltzner, B., & Munk, A. (2021). Analysis of patchclamp recordings: model-free multiscale methods and software. European Biophysics Journal, 50(2), 187-209. https://doi.org/10.1007/s00249-021-01506-8

Vancouver

Pein F, Eltzner B, Munk A. Analysis of patchclamp recordings: model-free multiscale methods and software. European Biophysics Journal. 2021 Mar 9;50(2):187-209. doi: 10.1007/s00249-021-01506-8

Author

Pein, Florian ; Eltzner, Benjamin ; Munk, Axel. / Analysis of patchclamp recordings : model-free multiscale methods and software. In: European Biophysics Journal. 2021 ; Vol. 50, No. 2. pp. 187-209.

Bibtex

@article{e92c64608d304b4db9981d79df36177b,
title = "Analysis of patchclamp recordings: model-free multiscale methods and software",
abstract = "Analysis of patchclamp recordings is often a challenging issue. We give practical guidance how such recordings can be analyzed using the model-free multiscale idealization methodology JSMURF, JULES, and HILDE. We provide an operational manual how to use the accompanying software available as an R-package and as a graphical user interface. This includes selection of the right approach and tuning of parameters. We also discuss advantages and disadvantages of model-free approaches in comparison to hidden Markov model approaches and explain how they complement each other.",
author = "Florian Pein and Benjamin Eltzner and Axel Munk",
year = "2021",
month = mar,
day = "9",
doi = "10.1007/s00249-021-01506-8",
language = "English",
volume = "50",
pages = "187--209",
journal = "European Biophysics Journal",
issn = "0175-7571",
publisher = "Springer Verlag",
number = "2",

}

RIS

TY - JOUR

T1 - Analysis of patchclamp recordings

T2 - model-free multiscale methods and software

AU - Pein, Florian

AU - Eltzner, Benjamin

AU - Munk, Axel

PY - 2021/3/9

Y1 - 2021/3/9

N2 - Analysis of patchclamp recordings is often a challenging issue. We give practical guidance how such recordings can be analyzed using the model-free multiscale idealization methodology JSMURF, JULES, and HILDE. We provide an operational manual how to use the accompanying software available as an R-package and as a graphical user interface. This includes selection of the right approach and tuning of parameters. We also discuss advantages and disadvantages of model-free approaches in comparison to hidden Markov model approaches and explain how they complement each other.

AB - Analysis of patchclamp recordings is often a challenging issue. We give practical guidance how such recordings can be analyzed using the model-free multiscale idealization methodology JSMURF, JULES, and HILDE. We provide an operational manual how to use the accompanying software available as an R-package and as a graphical user interface. This includes selection of the right approach and tuning of parameters. We also discuss advantages and disadvantages of model-free approaches in comparison to hidden Markov model approaches and explain how they complement each other.

U2 - 10.1007/s00249-021-01506-8

DO - 10.1007/s00249-021-01506-8

M3 - Journal article

C2 - 33837454

VL - 50

SP - 187

EP - 209

JO - European Biophysics Journal

JF - European Biophysics Journal

SN - 0175-7571

IS - 2

ER -