Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
}
TY - JOUR
T1 - Assessing developmental outcomes of children from Kilifi, Kenya following prophylaxis for seizures in Cerebral Malaria
AU - Abubakar, Amina
AU - Van de Vijver, Fons J. R.
AU - Mithwani, Sadik
AU - Obiero, Elizabeth
AU - Lewa, Naomi
AU - Kenga, Simon
AU - Katana, Khamis
AU - Holding, Penny
PY - 2007/5
Y1 - 2007/5
N2 - The purpose of the study was to develop a culture-informed measure of developmental outcome and to apply it to detect differences in developmental level between children with cerebral malaria enrolled in a clinical trial to control seizures during the acute phase of the illness. The instrument was administered to a sample of 180 children, three and 12 months after discharge from hospital. The measure demonstrated high internal consistency, good inter-observer reliability, age sensitivity and strong relations with parental report of child functioning. No association was found between performance, or change in performance, with the prophylactic regime administered. The results suggested that the use of Phenobarbital in controlling provoked seizures has no observable effect on cognitive function.
AB - The purpose of the study was to develop a culture-informed measure of developmental outcome and to apply it to detect differences in developmental level between children with cerebral malaria enrolled in a clinical trial to control seizures during the acute phase of the illness. The instrument was administered to a sample of 180 children, three and 12 months after discharge from hospital. The measure demonstrated high internal consistency, good inter-observer reliability, age sensitivity and strong relations with parental report of child functioning. No association was found between performance, or change in performance, with the prophylactic regime administered. The results suggested that the use of Phenobarbital in controlling provoked seizures has no observable effect on cognitive function.
KW - assessment
KW - cerebral malaria
KW - Kenya
KW - prophylaxis
KW - seizures
U2 - 10.1177/1359105307076230
DO - 10.1177/1359105307076230
M3 - Journal article
VL - 12
SP - 412
EP - 430
JO - Journal of Health Psychology
JF - Journal of Health Psychology
SN - 1461-7277
IS - 3
ER -