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  • Bayesian_clinical_trial_designs___Another_option.98997

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Bayesian clinical trial designs: another option for trauma trials?

Research output: Contribution to Journal/Magazine › Journal article › peer-review

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Bayesian clinical trial designs: another option for trauma trials? / UK-REBOA Trial Investigators.
In: Journal of Trauma and Acute Care Surgery, Vol. 83, No. 4, 10.2017, p. 736-741.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

UK-REBOA Trial Investigators 2017, 'Bayesian clinical trial designs: another option for trauma trials?', Journal of Trauma and Acute Care Surgery, vol. 83, no. 4, pp. 736-741. https://doi.org/10.1097/TA.0000000000001638

APA

UK-REBOA Trial Investigators (2017). Bayesian clinical trial designs: another option for trauma trials? Journal of Trauma and Acute Care Surgery, 83(4), 736-741. https://doi.org/10.1097/TA.0000000000001638

Vancouver

UK-REBOA Trial Investigators. Bayesian clinical trial designs: another option for trauma trials? Journal of Trauma and Acute Care Surgery. 2017 Oct;83(4):736-741. Epub 2017 Jul 8. doi: 10.1097/TA.0000000000001638

Author

UK-REBOA Trial Investigators. / Bayesian clinical trial designs : another option for trauma trials?. In: Journal of Trauma and Acute Care Surgery. 2017 ; Vol. 83, No. 4. pp. 736-741.

Bibtex

@article{70c445e93bfd434f8dd2ea3e30320ad0,
title = "Bayesian clinical trial designs: another option for trauma trials?",
abstract = "Conducting clinical trials in trauma care is challenging. As new treatments become available, we are faced with the dilemma of how to confirm their effectiveness, and strengthen the evidence base. Randomized controlled trials are the gold standard, but target groups in trauma care are often small and specialized, making the classical approach to trial design difficult. Bayesian designs represent an innovative means of increasing trial efficiency, and conducting trials with more realistic sample sizes. This article examines the design of such trials, using the UK-REBOA Trial as an example.",
author = "Jansen, {Jan O.} and Pallmann, {Philip Steffen} and Graeme MacLennan and Campbell, {Marion K.} and {UK-REBOA Trial Investigators}",
note = "Copyright {\textcopyright} 2017 Ovid Technologies, Inc. All Rights Reserved",
year = "2017",
month = oct,
doi = "10.1097/TA.0000000000001638",
language = "English",
volume = "83",
pages = "736--741",
journal = "Journal of Trauma and Acute Care Surgery",
issn = "2163-0755",
publisher = "Lippincott Williams and Wilkins",
number = "4",

}

RIS

TY - JOUR

T1 - Bayesian clinical trial designs

T2 - another option for trauma trials?

AU - Jansen, Jan O.

AU - Pallmann, Philip Steffen

AU - MacLennan, Graeme

AU - Campbell, Marion K.

AU - UK-REBOA Trial Investigators

N1 - Copyright © 2017 Ovid Technologies, Inc. All Rights Reserved

PY - 2017/10

Y1 - 2017/10

N2 - Conducting clinical trials in trauma care is challenging. As new treatments become available, we are faced with the dilemma of how to confirm their effectiveness, and strengthen the evidence base. Randomized controlled trials are the gold standard, but target groups in trauma care are often small and specialized, making the classical approach to trial design difficult. Bayesian designs represent an innovative means of increasing trial efficiency, and conducting trials with more realistic sample sizes. This article examines the design of such trials, using the UK-REBOA Trial as an example.

AB - Conducting clinical trials in trauma care is challenging. As new treatments become available, we are faced with the dilemma of how to confirm their effectiveness, and strengthen the evidence base. Randomized controlled trials are the gold standard, but target groups in trauma care are often small and specialized, making the classical approach to trial design difficult. Bayesian designs represent an innovative means of increasing trial efficiency, and conducting trials with more realistic sample sizes. This article examines the design of such trials, using the UK-REBOA Trial as an example.

U2 - 10.1097/TA.0000000000001638

DO - 10.1097/TA.0000000000001638

M3 - Journal article

VL - 83

SP - 736

EP - 741

JO - Journal of Trauma and Acute Care Surgery

JF - Journal of Trauma and Acute Care Surgery

SN - 2163-0755

IS - 4

ER -