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Control of innate-like B cell location for compartmentalised IgM production

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Control of innate-like B cell location for compartmentalised IgM production. / Jackson-Jones, Lucy H; Bénézech, Cécile.
In: Current opinion in immunology, Vol. 50, 02.2018, p. 9-13.

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Jackson-Jones LH, Bénézech C. Control of innate-like B cell location for compartmentalised IgM production. Current opinion in immunology. 2018 Feb;50:9-13. Epub 2017 Nov 5. doi: 10.1016/j.coi.2017.10.006

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Jackson-Jones, Lucy H ; Bénézech, Cécile. / Control of innate-like B cell location for compartmentalised IgM production. In: Current opinion in immunology. 2018 ; Vol. 50. pp. 9-13.

Bibtex

@article{94a2cfaa33714dfba39b0be2d3dc0e65,
title = "Control of innate-like B cell location for compartmentalised IgM production",
abstract = "Natural IgM are crucial for early protection against infection and play an important homeostatic function by clearing dead cells. The production of IgM is ensured by a population of B cells with innate-like properties: their response is rapidly activated by innate signals early during the onset of infection. The main reservoir of innate-like B cells (IBCs) are the serous cavities, but their maintenance and activation depends on their relocation to a variety of lymphoid tissues. Recent advances indicate that fat-associated lymphoid clusters (FALCs) and milky spots contribute to local IgM secretion and play a central role in the localisation and regulation of IBC function.",
author = "Jackson-Jones, {Lucy H} and C{\'e}cile B{\'e}n{\'e}zech",
note = "Copyright {\textcopyright} 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.",
year = "2018",
month = feb,
doi = "10.1016/j.coi.2017.10.006",
language = "English",
volume = "50",
pages = "9--13",
journal = "Current opinion in immunology",
issn = "0952-7915",
publisher = "Elsevier Ltd",

}

RIS

TY - JOUR

T1 - Control of innate-like B cell location for compartmentalised IgM production

AU - Jackson-Jones, Lucy H

AU - Bénézech, Cécile

N1 - Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

PY - 2018/2

Y1 - 2018/2

N2 - Natural IgM are crucial for early protection against infection and play an important homeostatic function by clearing dead cells. The production of IgM is ensured by a population of B cells with innate-like properties: their response is rapidly activated by innate signals early during the onset of infection. The main reservoir of innate-like B cells (IBCs) are the serous cavities, but their maintenance and activation depends on their relocation to a variety of lymphoid tissues. Recent advances indicate that fat-associated lymphoid clusters (FALCs) and milky spots contribute to local IgM secretion and play a central role in the localisation and regulation of IBC function.

AB - Natural IgM are crucial for early protection against infection and play an important homeostatic function by clearing dead cells. The production of IgM is ensured by a population of B cells with innate-like properties: their response is rapidly activated by innate signals early during the onset of infection. The main reservoir of innate-like B cells (IBCs) are the serous cavities, but their maintenance and activation depends on their relocation to a variety of lymphoid tissues. Recent advances indicate that fat-associated lymphoid clusters (FALCs) and milky spots contribute to local IgM secretion and play a central role in the localisation and regulation of IBC function.

U2 - 10.1016/j.coi.2017.10.006

DO - 10.1016/j.coi.2017.10.006

M3 - Review article

C2 - 29078198

VL - 50

SP - 9

EP - 13

JO - Current opinion in immunology

JF - Current opinion in immunology

SN - 0952-7915

ER -