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Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Conference contribution/Paper › peer-review
Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Conference contribution/Paper › peer-review
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TY - GEN
T1 - Coulomb blockade oscillations in biological ion channels
AU - Kaufman, Igor Khaimovich
AU - Gibby, William
AU - Luchinsky, Dmitry
AU - McClintock, Peter Vaughan Elsmere
AU - Eisenberg, Robert S.
PY - 2015/6/2
Y1 - 2015/6/2
N2 - The conduction and selectivity of calcium/sodium ion channels are described in terms of ionic Coulomb blockade, a phenomenon based on charge discreteness, an electrostatic exclusion principle, and stochastic ion motion through the channel. This novel approach provides a unified explanation of numerous observed and modelled conductance and selectivity phenomena, including the anomalous mole fraction effect and discrete conduction bands. Ionic Coulomb blockade and resonant conduction are similar to electronic Coulomb blockade and resonant tunnelling in quantum dots. The model is equally applicable to other nanopores.
AB - The conduction and selectivity of calcium/sodium ion channels are described in terms of ionic Coulomb blockade, a phenomenon based on charge discreteness, an electrostatic exclusion principle, and stochastic ion motion through the channel. This novel approach provides a unified explanation of numerous observed and modelled conductance and selectivity phenomena, including the anomalous mole fraction effect and discrete conduction bands. Ionic Coulomb blockade and resonant conduction are similar to electronic Coulomb blockade and resonant tunnelling in quantum dots. The model is equally applicable to other nanopores.
U2 - 10.1109/ICNF.2015.7288558
DO - 10.1109/ICNF.2015.7288558
M3 - Conference contribution/Paper
BT - Noise and Fluctuations (ICNF), 2015 International Conference on
PB - IEEE
ER -