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Exocytosis in adrenal chromaffin cells

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Exocytosis in adrenal chromaffin cells. / Burgoyne, R. D.; Morgan, A.; Robinson, I. et al.
In: Journal of Anatomy, Vol. 183, No. 2, 1993, p. 309-314.

Research output: Contribution to Journal/MagazineJournal articlepeer-review

Harvard

Burgoyne, RD, Morgan, A, Robinson, I, Pender, N & Cheek, TR 1993, 'Exocytosis in adrenal chromaffin cells', Journal of Anatomy, vol. 183, no. 2, pp. 309-314.

APA

Burgoyne, R. D., Morgan, A., Robinson, I., Pender, N., & Cheek, T. R. (1993). Exocytosis in adrenal chromaffin cells. Journal of Anatomy, 183(2), 309-314.

Vancouver

Burgoyne RD, Morgan A, Robinson I, Pender N, Cheek TR. Exocytosis in adrenal chromaffin cells. Journal of Anatomy. 1993;183(2):309-314.

Author

Burgoyne, R. D. ; Morgan, A. ; Robinson, I. et al. / Exocytosis in adrenal chromaffin cells. In: Journal of Anatomy. 1993 ; Vol. 183, No. 2. pp. 309-314.

Bibtex

@article{870dea77546e4db0983dba67124bb8b1,
title = "Exocytosis in adrenal chromaffin cells",
abstract = "Recent advances have led to an increased understanding of the Ca2+-signalling pathway leading to exocytosis in bovine adrenal chromaffin cells. Video-imaging studies have allowed the temporal and spatial aspects of the Ca2+ signal to be investigated in detail. Ca2+ entry at the plasma membrane appears to be crucial for the activation of exocytosis. Ca2+ can enter through the nicotinic channel or characterised voltage-activated channels, or through other poorly defined pathways due to a variety of agonists. Emptying of internal Ca2+ stores is sufficient to activate a Ca2+ entry pathway. The elevation of cytosolic Ca2+ concentration leads to a reorganisation of the cortical actin network and to the triggering of exocytosis. Studies on permeabilised chromaffin cells have resulted in the identification of some of the proteins that control Ca2+-dependent exocytosis. These include the peripheral plasma membrane protein annexin II and the cytosolic proteins, protein kinase C and 14-3-3 proteins (Exol).",
author = "Burgoyne, {R. D.} and A. Morgan and I. Robinson and N. Pender and Cheek, {T. R.}",
year = "1993",
language = "English",
volume = "183",
pages = "309--314",
journal = "Journal of Anatomy",
issn = "0021-8782",
publisher = "Wiley-Blackwell",
number = "2",

}

RIS

TY - JOUR

T1 - Exocytosis in adrenal chromaffin cells

AU - Burgoyne, R. D.

AU - Morgan, A.

AU - Robinson, I.

AU - Pender, N.

AU - Cheek, T. R.

PY - 1993

Y1 - 1993

N2 - Recent advances have led to an increased understanding of the Ca2+-signalling pathway leading to exocytosis in bovine adrenal chromaffin cells. Video-imaging studies have allowed the temporal and spatial aspects of the Ca2+ signal to be investigated in detail. Ca2+ entry at the plasma membrane appears to be crucial for the activation of exocytosis. Ca2+ can enter through the nicotinic channel or characterised voltage-activated channels, or through other poorly defined pathways due to a variety of agonists. Emptying of internal Ca2+ stores is sufficient to activate a Ca2+ entry pathway. The elevation of cytosolic Ca2+ concentration leads to a reorganisation of the cortical actin network and to the triggering of exocytosis. Studies on permeabilised chromaffin cells have resulted in the identification of some of the proteins that control Ca2+-dependent exocytosis. These include the peripheral plasma membrane protein annexin II and the cytosolic proteins, protein kinase C and 14-3-3 proteins (Exol).

AB - Recent advances have led to an increased understanding of the Ca2+-signalling pathway leading to exocytosis in bovine adrenal chromaffin cells. Video-imaging studies have allowed the temporal and spatial aspects of the Ca2+ signal to be investigated in detail. Ca2+ entry at the plasma membrane appears to be crucial for the activation of exocytosis. Ca2+ can enter through the nicotinic channel or characterised voltage-activated channels, or through other poorly defined pathways due to a variety of agonists. Emptying of internal Ca2+ stores is sufficient to activate a Ca2+ entry pathway. The elevation of cytosolic Ca2+ concentration leads to a reorganisation of the cortical actin network and to the triggering of exocytosis. Studies on permeabilised chromaffin cells have resulted in the identification of some of the proteins that control Ca2+-dependent exocytosis. These include the peripheral plasma membrane protein annexin II and the cytosolic proteins, protein kinase C and 14-3-3 proteins (Exol).

M3 - Journal article

C2 - 8300418

AN - SCOPUS:0027454024

VL - 183

SP - 309

EP - 314

JO - Journal of Anatomy

JF - Journal of Anatomy

SN - 0021-8782

IS - 2

ER -