Final published version
Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Chapter
| Publication date | 7/01/2017 |
|---|---|
| Host publication | Methods in Molecular Biology |
| Place of Publication | New York |
| Publisher | Humana Press Inc. |
| Pages | 343-365 |
| Number of pages | 23 |
| ISBN (electronic) | 9781493967865 |
| ISBN (print) | 9781493967841 |
| <mark>Original language</mark> | English |
| Name | Methods in Molecular Biology |
|---|---|
| Volume | 1559 |
| ISSN (Print) | 1064-3745 |
In this chapter we describe in detail the surgical and imaging techniques employed for the study of the anatomical routes of drainage of cerebrospinal fluid (CSF) and interstitial fluid (ISF) from the brain. The types of tracers, sites of injection, and volumes injected are crucial. For example, when testing the drainage of ISF from the parenchyma, volumes larger than 0.5 μL result in spillage of ISF into the ventricular CSF.