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Kinetic model of selectivity and conductivity of the KcsA filter

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Kinetic model of selectivity and conductivity of the KcsA filter. / Gibby, W. A. T.; Luchinsky, D. G.; Kaufman, Igor Khaimovich et al.
In: arxiv.org, 11.04.2017.

Research output: Contribution to Journal/MagazineJournal article

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@article{4ab3033c05e34a20b32eeb4b1c43eca2,
title = "Kinetic model of selectivity and conductivity of the KcsA filter",
abstract = "We introduce a self-consistent multi-species kinetic theory based on the structure of the narrow voltage-gated potassium channel. Transition rates depend on a complete energy spectrum with contributions including the dehydration amongst species, interaction with the dipolar charge of the filter and, bulk solution properties. It displays high selectivity between species coexisting with fast conductivity, and Coulomb blockade phenomena, and it fits well to data.",
keywords = "physics.bio-ph",
author = "Gibby, {W. A. T.} and Luchinsky, {D. G.} and Kaufman, {Igor Khaimovich} and A. Ward and McClintock, {P. V. E.}",
year = "2017",
month = apr,
day = "11",
language = "English",
journal = "arxiv.org",

}

RIS

TY - JOUR

T1 - Kinetic model of selectivity and conductivity of the KcsA filter

AU - Gibby, W. A. T.

AU - Luchinsky, D. G.

AU - Kaufman, Igor Khaimovich

AU - Ward, A.

AU - McClintock, P. V. E.

PY - 2017/4/11

Y1 - 2017/4/11

N2 - We introduce a self-consistent multi-species kinetic theory based on the structure of the narrow voltage-gated potassium channel. Transition rates depend on a complete energy spectrum with contributions including the dehydration amongst species, interaction with the dipolar charge of the filter and, bulk solution properties. It displays high selectivity between species coexisting with fast conductivity, and Coulomb blockade phenomena, and it fits well to data.

AB - We introduce a self-consistent multi-species kinetic theory based on the structure of the narrow voltage-gated potassium channel. Transition rates depend on a complete energy spectrum with contributions including the dehydration amongst species, interaction with the dipolar charge of the filter and, bulk solution properties. It displays high selectivity between species coexisting with fast conductivity, and Coulomb blockade phenomena, and it fits well to data.

KW - physics.bio-ph

M3 - Journal article

JO - arxiv.org

JF - arxiv.org

M1 - 1704.03267

ER -