Final published version
Licence: CC BY: Creative Commons Attribution 4.0 International License
Research output: Contribution to Journal/Magazine › Review article › peer-review
Research output: Contribution to Journal/Magazine › Review article › peer-review
}
TY - JOUR
T1 - Lumpy Skin Disease
T2 - Insights into Molecular Pathogenesis and Control Strategies
AU - Haider, Ali
AU - Abbas, Zaheer
AU - Taqveem, Ahsen
AU - Ali, Abid
AU - Khurshid, Mohsin
AU - Naggar, Rania F. El
AU - Rohaim, Mohammed
AU - Munir, Muhammad
PY - 2024/11/13
Y1 - 2024/11/13
N2 - Lumpy skin disease (LSD) is a viral infection that affects buffaloes and cattle across various regions, including both tropical and temperate climates. Intriguingly, the virus–carrying skin sores remain the primary source of infection for extended periods, exacerbated by the abundance of vectors in disease–endemic countries. Recent scientific advances have revealed the molecular aspects of LSD and offered improved vaccines and valuable antiviral targets. This review summarizes the molecular features of LSD and its effect on various livestock species. We then provide an extensive discussion on the transmission dynamics of LSD and the roles of vectors in its continued spread among livestock populations. Additionally, this review critically analyses the rationales behind, as well as the affordability and effectiveness, of current control strategies worldwide.
AB - Lumpy skin disease (LSD) is a viral infection that affects buffaloes and cattle across various regions, including both tropical and temperate climates. Intriguingly, the virus–carrying skin sores remain the primary source of infection for extended periods, exacerbated by the abundance of vectors in disease–endemic countries. Recent scientific advances have revealed the molecular aspects of LSD and offered improved vaccines and valuable antiviral targets. This review summarizes the molecular features of LSD and its effect on various livestock species. We then provide an extensive discussion on the transmission dynamics of LSD and the roles of vectors in its continued spread among livestock populations. Additionally, this review critically analyses the rationales behind, as well as the affordability and effectiveness, of current control strategies worldwide.
U2 - 10.3390/vetsci11110561
DO - 10.3390/vetsci11110561
M3 - Review article
VL - 11
JO - Veterinary Sciences
JF - Veterinary Sciences
SN - 2306-7381
IS - 11
M1 - 561
ER -