Research output: Contribution to Journal/Magazine › Review article › peer-review
Research output: Contribution to Journal/Magazine › Review article › peer-review
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TY - JOUR
T1 - Obesity and mortality
T2 - Summary of best evidence with explanations for the obesity paradox
AU - Logue, Jennifer
AU - Sattar, Naveed
PY - 2010
Y1 - 2010
N2 - The link between obesity and increased risk of mortality is well established. However, those who are obese have greater survival when they have chronic diseases such as rheumatoid arthritis or cardiac failure; this is known as the "obesity paradox". The obesity paradox is most probably attributable to obese individuals being more susceptible to milder forms of disease than normal-weight individuals, although other mechanisms may also operate. The benefits of weight loss in the general population are also unclear, as some study participants also lose weight through disease. Further work is required to help guide weight recommendations in both healthy individuals and those with chronic diseases.
AB - The link between obesity and increased risk of mortality is well established. However, those who are obese have greater survival when they have chronic diseases such as rheumatoid arthritis or cardiac failure; this is known as the "obesity paradox". The obesity paradox is most probably attributable to obese individuals being more susceptible to milder forms of disease than normal-weight individuals, although other mechanisms may also operate. The benefits of weight loss in the general population are also unclear, as some study participants also lose weight through disease. Further work is required to help guide weight recommendations in both healthy individuals and those with chronic diseases.
KW - Cardiovascular disease
KW - Death
KW - Mortality
KW - Obesity
KW - Obesity paradox
M3 - Review article
AN - SCOPUS:78751481426
SP - 11
EP - 13
JO - Heart and Metabolism
JF - Heart and Metabolism
SN - 1566-0338
IS - 48
ER -