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    Rights statement: Copyright 2021 American Institute of Physics. The following article appeared in Applied Physics Letters, 119, (5), 2021 and may be found at http://dx.doi.org/10.1063/5.0062787 This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics.

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On-demand cold plasma activation of acetyl donors for bacteria and virus decontamination

Research output: Contribution to Journal/Magazine › Journal article › peer-review

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On-demand cold plasma activation of acetyl donors for bacteria and virus decontamination. / Szili, E.J.; Ghimire, B.; Patenall, B.L. et al.
In: Applied Physics Letters, Vol. 119, No. 5, 054104, 02.08.2021.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Szili, EJ, Ghimire, B, Patenall, BL, Rohaim, M, Mistry, D, Fellows, A, Munir, M, Jenkins, ATA & Short, RD 2021, 'On-demand cold plasma activation of acetyl donors for bacteria and virus decontamination', Applied Physics Letters, vol. 119, no. 5, 054104. https://doi.org/10.1063/5.0062787

APA

Szili, E. J., Ghimire, B., Patenall, B. L., Rohaim, M., Mistry, D., Fellows, A., Munir, M., Jenkins, A. T. A., & Short, R. D. (2021). On-demand cold plasma activation of acetyl donors for bacteria and virus decontamination. Applied Physics Letters, 119(5), Article 054104. https://doi.org/10.1063/5.0062787

Vancouver

Szili EJ, Ghimire B, Patenall BL, Rohaim M, Mistry D, Fellows A et al. On-demand cold plasma activation of acetyl donors for bacteria and virus decontamination. Applied Physics Letters. 2021 Aug 2;119(5):054104. doi: 10.1063/5.0062787

Author

Szili, E.J. ; Ghimire, B. ; Patenall, B.L. et al. / On-demand cold plasma activation of acetyl donors for bacteria and virus decontamination. In: Applied Physics Letters. 2021 ; Vol. 119, No. 5.

Bibtex

@article{effa81359fdb48bfa2698b97c55034a1,
title = "On-demand cold plasma activation of acetyl donors for bacteria and virus decontamination",
abstract = "Antibiotics are commonly used as the first line of defense in the treatment of infectious diseases. However, the rise of antimicrobial resistance (AMR) is rendering many antibiotics less effective. Consequently, effective non-antibiotic antimicrobial strategies are urgently needed to combat AMR. This paper presents a strategy utilizing cold plasma for the {"}on-demand{"}activation of acetyl donor molecules. The process generates an aqueous-based antimicrobial formulation comprising a rich mixture of highly oxidizing molecules: peracetic acid, hydrogen peroxide, and other reactive oxygen and nitrogen species. The synergistic potent oxidative action between these molecules is shown to be highly effective at eradicating common wound pathogenic bacteria (Pseudomonas aeruginosa and Staphylococcus aureus) and at inactivating a virus (SARS-CoV-2). ",
keywords = "Antibiotics, Bacteria, Chemical activation, Molecules, Viruses, Antimicrobial resistances, Cold plasmas, Donor molecules, Infectious disease, Pathogenic bacterium, Peracetic acids, Pseudomonas aeruginosa, Reactive oxygen and nitrogen species, Diseases",
author = "E.J. Szili and B. Ghimire and B.L. Patenall and M. Rohaim and D. Mistry and A. Fellows and M. Munir and A.T.A. Jenkins and R.D. Short",
note = "Copyright 2021 American Institute of Physics. The following article appeared in Applied Physics Letters, 119, (5), 2021 and may be found at http://dx.doi.org/10.1063/5.0062787 This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics. ",
year = "2021",
month = aug,
day = "2",
doi = "10.1063/5.0062787",
language = "English",
volume = "119",
journal = "Applied Physics Letters",
issn = "0003-6951",
publisher = "American Institute of Physics Inc.",
number = "5",

}

RIS

TY - JOUR

T1 - On-demand cold plasma activation of acetyl donors for bacteria and virus decontamination

AU - Szili, E.J.

AU - Ghimire, B.

AU - Patenall, B.L.

AU - Rohaim, M.

AU - Mistry, D.

AU - Fellows, A.

AU - Munir, M.

AU - Jenkins, A.T.A.

AU - Short, R.D.

N1 - Copyright 2021 American Institute of Physics. The following article appeared in Applied Physics Letters, 119, (5), 2021 and may be found at http://dx.doi.org/10.1063/5.0062787 This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics.

PY - 2021/8/2

Y1 - 2021/8/2

N2 - Antibiotics are commonly used as the first line of defense in the treatment of infectious diseases. However, the rise of antimicrobial resistance (AMR) is rendering many antibiotics less effective. Consequently, effective non-antibiotic antimicrobial strategies are urgently needed to combat AMR. This paper presents a strategy utilizing cold plasma for the "on-demand"activation of acetyl donor molecules. The process generates an aqueous-based antimicrobial formulation comprising a rich mixture of highly oxidizing molecules: peracetic acid, hydrogen peroxide, and other reactive oxygen and nitrogen species. The synergistic potent oxidative action between these molecules is shown to be highly effective at eradicating common wound pathogenic bacteria (Pseudomonas aeruginosa and Staphylococcus aureus) and at inactivating a virus (SARS-CoV-2).

AB - Antibiotics are commonly used as the first line of defense in the treatment of infectious diseases. However, the rise of antimicrobial resistance (AMR) is rendering many antibiotics less effective. Consequently, effective non-antibiotic antimicrobial strategies are urgently needed to combat AMR. This paper presents a strategy utilizing cold plasma for the "on-demand"activation of acetyl donor molecules. The process generates an aqueous-based antimicrobial formulation comprising a rich mixture of highly oxidizing molecules: peracetic acid, hydrogen peroxide, and other reactive oxygen and nitrogen species. The synergistic potent oxidative action between these molecules is shown to be highly effective at eradicating common wound pathogenic bacteria (Pseudomonas aeruginosa and Staphylococcus aureus) and at inactivating a virus (SARS-CoV-2).

KW - Antibiotics

KW - Bacteria

KW - Chemical activation

KW - Molecules

KW - Viruses

KW - Antimicrobial resistances

KW - Cold plasmas

KW - Donor molecules

KW - Infectious disease

KW - Pathogenic bacterium

KW - Peracetic acids

KW - Pseudomonas aeruginosa

KW - Reactive oxygen and nitrogen species

KW - Diseases

U2 - 10.1063/5.0062787

DO - 10.1063/5.0062787

M3 - Journal article

VL - 119

JO - Applied Physics Letters

JF - Applied Physics Letters

SN - 0003-6951

IS - 5

M1 - 054104

ER -