Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Chapter
Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Chapter
}
TY - CHAP
T1 - Pathology of peste des petits ruminants virus infection in small ruminants and concurrent infections
AU - Kul, Oguz
AU - Atmaca, Hasan Tarik
AU - Munir, Muhammad
PY - 2015/1/1
Y1 - 2015/1/1
N2 - Peste des petits ruminant (PPR) is a systemic viral disease of goats and sheep characterized by gastrointestinal and respiratory system lesions with high rate of mortality. Rhinitis, conjunctivitis, serous-mucopurulent naso-ocular discharge, pneumonia, coughing, dispnea, erosive-ulcerative oral lesions, and diarrhea are the most prominent clinicopathological features of the disease. Histopathologically, pseudomembraneous stomatitis, necrotic tonsillitis, fibrinohemorrhagic enteritis, and proliferative interstitial pneoumonia are seen. Syncytial cells and cytoplasmic and/or nuclear eosinophilic inclusion bodies are considered as pathognomonic. Like the other morbilli viruses, PPR virus can also cause lesions in the kidney, brain, and abomasum. The PPRV tropism can be explained by the mechanism in which PPRV binds to receptors on the cell surface. The PPR in small ruminants often shows coassociation with secondary viral, bacterial, and parasitary infections.
AB - Peste des petits ruminant (PPR) is a systemic viral disease of goats and sheep characterized by gastrointestinal and respiratory system lesions with high rate of mortality. Rhinitis, conjunctivitis, serous-mucopurulent naso-ocular discharge, pneumonia, coughing, dispnea, erosive-ulcerative oral lesions, and diarrhea are the most prominent clinicopathological features of the disease. Histopathologically, pseudomembraneous stomatitis, necrotic tonsillitis, fibrinohemorrhagic enteritis, and proliferative interstitial pneoumonia are seen. Syncytial cells and cytoplasmic and/or nuclear eosinophilic inclusion bodies are considered as pathognomonic. Like the other morbilli viruses, PPR virus can also cause lesions in the kidney, brain, and abomasum. The PPRV tropism can be explained by the mechanism in which PPRV binds to receptors on the cell surface. The PPR in small ruminants often shows coassociation with secondary viral, bacterial, and parasitary infections.
KW - canine distemper virus
KW - neutrophil leukocyte
KW - syncytial cell
KW - goat flock
KW - Interalveolar Septum
U2 - 10.1007/978-3-662-45165-6_7
DO - 10.1007/978-3-662-45165-6_7
M3 - Chapter
AN - SCOPUS:84943382537
SN - 9783662451649
SP - 119
EP - 131
BT - Peste Des Petits Ruminants Virus
A2 - Munir, Muhammad
PB - Springer Berlin Heidelberg
ER -