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Sequence analysis and biological characterization of virulent Avian avulavirus 1 isolated from asymptomatic migratory fowl

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Sequence analysis and biological characterization of virulent Avian avulavirus 1 isolated from asymptomatic migratory fowl. / Ul-Rahman, Aziz; Yaqub, T; Imran, M et al.
In: Acta virologica, Vol. 63, No. 2, 03.05.2019, p. 223-228.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Ul-Rahman, A, Yaqub, T, Imran, M, Habib, M, Sohail, T, Mukhtar, N, Shahid, MF, Munir, M & Shabbir, MZ 2019, 'Sequence analysis and biological characterization of virulent Avian avulavirus 1 isolated from asymptomatic migratory fowl', Acta virologica, vol. 63, no. 2, pp. 223-228. https://doi.org/10.4149/av_2019_208

APA

Ul-Rahman, A., Yaqub, T., Imran, M., Habib, M., Sohail, T., Mukhtar, N., Shahid, M. F., Munir, M., & Shabbir, M. Z. (2019). Sequence analysis and biological characterization of virulent Avian avulavirus 1 isolated from asymptomatic migratory fowl. Acta virologica, 63(2), 223-228. Advance online publication. https://doi.org/10.4149/av_2019_208

Vancouver

Ul-Rahman A, Yaqub T, Imran M, Habib M, Sohail T, Mukhtar N et al. Sequence analysis and biological characterization of virulent Avian avulavirus 1 isolated from asymptomatic migratory fowl. Acta virologica. 2019 May 3;63(2):223-228. Epub 2019 May 3. doi: 10.4149/av_2019_208

Author

Ul-Rahman, Aziz ; Yaqub, T ; Imran, M et al. / Sequence analysis and biological characterization of virulent Avian avulavirus 1 isolated from asymptomatic migratory fowl. In: Acta virologica. 2019 ; Vol. 63, No. 2. pp. 223-228.

Bibtex

@article{e61e549a5be34ce9ba76a9d5e031dc92,
title = "Sequence analysis and biological characterization of virulent Avian avulavirus 1 isolated from asymptomatic migratory fowl",
abstract = "Continuous monitoring and surveillance of avian avulaviruses (AAvVs) in water/migratory fowl is imperative to ascertain the evolutionary dynamics of these viruses. Here, we report genomic and amino acid characteristics of two AAvVs strains isolated from asymptomatic waterfowl (Anas carolinensis). Sequence characteristics including the presence of virulent motif (112RRQKR↓F117) and biological assessment confirmed the virulent nature of study isolates. Phylogenetic analysis of complete fusion (F) and hemagglutinin-neuraminidase (HN), and hyper-variable region of F gene revealed clustering of both strains within genotype VII and sub-genotype VIIi. The inferred residue analysis of complete F and HN genes revealed a number of substitutions in functionally and structurally important motif/s compared to reference strains of each genotype (I-XI). This study concludes an evolutionary nature of avian avulavaris 1 (AAvV-1), ascertaining continuous surveillance of migratory fowl to better elucidate their infection, epidemiology and subsequent impacts on commercial and backyard poultry. Keywords: virulent AAvV-1; migratory fowl; genetic characterization; evolutionary analysis; Pakistan.",
author = "Aziz Ul-Rahman and T Yaqub and M Imran and M Habib and T Sohail and N Mukhtar and Shahid, {M F} and Muhammad Munir and Shabbir, {M Z}",
year = "2019",
month = may,
day = "3",
doi = "10.4149/av_2019_208",
language = "English",
volume = "63",
pages = "223--228",
journal = "Acta virologica",
issn = "0001-723X",
publisher = "AEP - Academic Electronic Press Ltd.",
number = "2",

}

RIS

TY - JOUR

T1 - Sequence analysis and biological characterization of virulent Avian avulavirus 1 isolated from asymptomatic migratory fowl

AU - Ul-Rahman, Aziz

AU - Yaqub, T

AU - Imran, M

AU - Habib, M

AU - Sohail, T

AU - Mukhtar, N

AU - Shahid, M F

AU - Munir, Muhammad

AU - Shabbir, M Z

PY - 2019/5/3

Y1 - 2019/5/3

N2 - Continuous monitoring and surveillance of avian avulaviruses (AAvVs) in water/migratory fowl is imperative to ascertain the evolutionary dynamics of these viruses. Here, we report genomic and amino acid characteristics of two AAvVs strains isolated from asymptomatic waterfowl (Anas carolinensis). Sequence characteristics including the presence of virulent motif (112RRQKR↓F117) and biological assessment confirmed the virulent nature of study isolates. Phylogenetic analysis of complete fusion (F) and hemagglutinin-neuraminidase (HN), and hyper-variable region of F gene revealed clustering of both strains within genotype VII and sub-genotype VIIi. The inferred residue analysis of complete F and HN genes revealed a number of substitutions in functionally and structurally important motif/s compared to reference strains of each genotype (I-XI). This study concludes an evolutionary nature of avian avulavaris 1 (AAvV-1), ascertaining continuous surveillance of migratory fowl to better elucidate their infection, epidemiology and subsequent impacts on commercial and backyard poultry. Keywords: virulent AAvV-1; migratory fowl; genetic characterization; evolutionary analysis; Pakistan.

AB - Continuous monitoring and surveillance of avian avulaviruses (AAvVs) in water/migratory fowl is imperative to ascertain the evolutionary dynamics of these viruses. Here, we report genomic and amino acid characteristics of two AAvVs strains isolated from asymptomatic waterfowl (Anas carolinensis). Sequence characteristics including the presence of virulent motif (112RRQKR↓F117) and biological assessment confirmed the virulent nature of study isolates. Phylogenetic analysis of complete fusion (F) and hemagglutinin-neuraminidase (HN), and hyper-variable region of F gene revealed clustering of both strains within genotype VII and sub-genotype VIIi. The inferred residue analysis of complete F and HN genes revealed a number of substitutions in functionally and structurally important motif/s compared to reference strains of each genotype (I-XI). This study concludes an evolutionary nature of avian avulavaris 1 (AAvV-1), ascertaining continuous surveillance of migratory fowl to better elucidate their infection, epidemiology and subsequent impacts on commercial and backyard poultry. Keywords: virulent AAvV-1; migratory fowl; genetic characterization; evolutionary analysis; Pakistan.

U2 - 10.4149/av_2019_208

DO - 10.4149/av_2019_208

M3 - Journal article

C2 - 31230452

VL - 63

SP - 223

EP - 228

JO - Acta virologica

JF - Acta virologica

SN - 0001-723X

IS - 2

ER -