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Medical and Pharmaceutical Statistics Research Unit

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  1. Journal article
  2. Published

    Bayesian methods for the design and interpretation of clinical trials in very rare diseases

    Hampson, L., Whitehead, J., Eleftheriou, D. & Brogan, P., 30/10/2014, In: Statistics in Medicine. 33, 24, p. 4186-4201 16 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. Published

    Bridging the gap: a review of dose investigations in paediatric investigation plans

    Hampson, L., Herold, R., Posch, M., Saperia, J. & Whitehead, A., 10/2014, In: British Journal of Clinical Pharmacology. 78, 4, p. 898-907 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  4. Published

    Flexible sequential designs for multi-arm clinical trials

    Magirr, D., Stallard, N. & Jaki, T., 30/08/2014, In: Statistics in Medicine. 33, 19, p. 3269-3279 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  5. Published

    A Bayesian approach to dose finding studies for cancer therapies: incorporating later cycles of therapy

    Sinclair, K. & Whitehead, A., 10/07/2014, In: Statistics in Medicine. 33, 15, p. 2665-2680 16 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  6. Published

    Manual vs. integrated automatic load-distributing band CPR with equal survival after out of hospital cardiac arrest: the randomized CIRC trial

    Wik, L., Olsen, J-A., Persse, D., Sterz, F., Lozano Jr, M., Brouwer, M. A., Westfall, M., Souders, C., Malzer, R., Grunsven, P. M. V., Travis, D., Whitehead, A., Herken, U. R. & Lerner, E. B., 06/2014, In: Resuscitation. 85, 6, p. 741-748 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  7. Published

    A comparison of methods for classifying samples as truly specific with confirmatory immunoassays

    Jaki, T., Lawo, J-P., Wolfsegger, M. J., Allacher, P. & Horling, F., 25/01/2014, In: Journal of Pharmaceutical and Biomedical Analysis. 88, p. 27-35 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  8. Published

    A hybrid method to estimate the minimum effective dose for monotone and non-monotone dose-response relationships

    Wolfsegger, M. J., Gutjahr, G., Engl, W. & Jaki, T., 2014, In: Biometrics. 70, 1, p. 103-109 7 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  9. Published

    Statistical evaluation of toxicological assays with zero or near-to-zero proportions or counts in the concurrent negative control group: a tutorial

    Jaki, T., Kitsche, A. & Hothorn, L. A., 2014, In: JP Journal of Biostatistics. 11, 1, p. 1-32 32 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  10. Published

    Estimation in AB/BA cross-over trials with application to bioequivalence studies with incomplete and complete data designs

    Jaki, T., Pallmann, P. & Wolfsegger, M. J., 30/12/2013, In: Statistics in Medicine. 32, 30, p. 5469-5483 15 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  11. Published

    Exercise and self-management for people with chronic knee, hip or lower back pain: a cluster randomised controlled trial of clinical and cost-effectiveness. Study protocol

    Walsh, N., Cramp, F., Palmer, S., Pollock, J., Hampson, L., Gooberman-Hill, R., Green, C., Jones, L., Phillips, S., Johnson, L. & Hurley, M., 12/2013, In: Physiotherapy. 99, 4, p. 352-357 6 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  12. Published

    Methodological quality of meta-analyses: matched-pairs comparison over time and between industry sponsored and academic-sponsored reports

    Lane, P. W., Higgins, J. P. T., Anagnostelis, B., Anzures-Cabrera, J., Baker, N. F., Cappelleri, J. C., Haughie, S., Hollis, S., Lewis, S. C., Moneuse, P. & Whitehead, A., 12/2013, In: Research Synthesis Methods. 4, 4, p. 342-350 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  13. Published

    A tool to assess the quality of a meta-analysis

    Higgins, J. P. T., Lane, P. W., Anagnostelis, B., Anzures-Cabrera, J., Baker, N. F., Cappelleri, J. C., Haughie, S., Hollis, S., Lewis, S. C., Moneuse, P. & Whitehead, A., 12/2013, In: Research Synthesis Methods. 4, 4, p. 351-366 16 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  14. Published

    Statistical evaluation of toxicological assays: Dunnett or Williams test? − take both

    Jaki, T. & Hothorn, L. A., 11/2013, In: Archives of Toxicology. 87, 11, p. 1901-1910 10 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  15. Published

    Planning multi-arm screening studies within the context of a drug development programme

    Wason, J., Jaki, T. & Stallard, N., 10/09/2013, In: Statistics in Medicine. 32, 20, p. 3424-3435 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  16. Published

    Multiplicity: discussion points from the PSI multiplicity expert group

    Phillips, A., Fletcher, C., Atkinson, G., Channon, E., Douiri, A., Jaki, T., Maca, J., Morgan, D., Roger, J. H. & Terrill, P., 09/2013, In: Pharmaceutical Statistics. 12, 5, p. 255-259 5 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  17. Published

    Differential effects of parental controls on adolescent substance use: for whom is the family most important?

    Fagan, A. A., Van Horn, M. L., Hawkins, J. D. & Jaki, T., 09/2013, In: Journal of Quantitative Criminology. 29, 3, p. 347-368 22 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  18. Published

    Analysing malaria drug trials on a per individual or a per clone basis: a comparison of methods

    Jaki, T., Parry, A., Winter, K. & Hastings, I., 30/07/2013, In: Statistics in Medicine. 32, 17, p. 3020-3038 19 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  19. Published

    Designing exploratory cancer trials using change in tumour size as primary endpoint

    Jaki, T., Andre, V., Su, T-L. & Whitehead, J., 10/07/2013, In: Statistics in Medicine. 32, 15, p. 2544-2554 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  20. Published

    Principles of dose finding studies in cancer: a comparison of trial designs

    Jaki, T., Clive, S. & Weir, C., 05/2013, In: Cancer Chemotherapy and Pharmacology. 71, 5, p. 1107-1114 8 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  21. Published

    Uptake of novel statistical methods for early phase clinical studies in the UK public sector

    Jaki, T., 04/2013, In: Clinical Trials. 10, 2, p. 344-346 3 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  22. Published

    Considerations on covariates and endpoints in multi-arm multi-stage clinical trials selecting all promising treatments

    Jaki, T. & Magirr, D., 30/03/2013, In: Statistics in Medicine. 32, 7, p. 1150-1163 14 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  23. Published

    Cost-utility analysis conducted alongside randomized controlled trials: Are economic end points considered in sample size calculations and does it matter?

    Hollingworth, W., McKell-Redwood, D., Hampson, L. & Metcalfe, C., 02/2013, In: Clinical Trials. 10, 1, p. 43-53 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  24. Published

    Group sequential tests for delayed responses

    Hampson, L. & Jennison, C., 01/2013, In: Journal of the Royal Statistical Society: Series B (Statistical Methodology). 75, 1, p. 3-54 52 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  25. Published

    Using regression mixture models with non-normal data: examining an ordered polytomous approach

    George, M., Yang, N., Van Horn, M. L., Smith, J., Jaki, T., Feaster, D., Maysn, K. & Howe, G., 2013, In: Journal of Statistical Computation and Simulation. 83, 4, p. 757-770 14 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  26. Published

    Finite mixtures for simultaneously modelling differential effects and non-normal distributions

    George, M., Yang, N., Jaki, T., Feaster, D., Lamont, A. E., Van Horn, M. L. & Wilson, D. K., 2013, In: Multivariate Behavioral Research. 48, 6, p. 816-844 29 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

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