Heritability of hippocampal subfield volumes using a twin and non-twin siblings design

Patel, S., Park, M. T. M., Devenyi, G. A., Patel, R., Masellis, M., Knight, J. & Chakravarty, M. M., 09/2017, In: Human Brain Mapping. 38, 9, p. 4337-4352 16 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Genetic epistasis regulates amyloid deposition in resilient aging

Felsky, D., Xu, J., Chibnik, L., Schneider, J., Knight, J., Kennedy, J. L., Bennett, D. A., De Jager, P. L. & Voineskos, A. N., 10/2017, In: Alzheimer's and Dementia. 13, 10, p. 1107-1116 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Unraveling DNA sequence to identify cerebral indicators of dementia risk

Masellis, M. & Knight, J., 16/01/2018, In: Neurology. 90, 3, p. 109 1 p.

Research output: Contribution to Journal/Magazine › Comment/debate

Examining the role of common and rare mitochondrial variants in schizophrenia

Gonçalves, V. F., Giamberardino, S. N., Crowley, J. J., Vawter, M. P., Saxena, R., Bulik, C. M., Yilmaz, Z., Hultman, C. M., Sklar, P., Kennedy, J. L., Sullivan, P. F. & Knight, J., 25/01/2018, In: PLoS ONE. 13, 1, e0191153.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Genome-wide association study of a nicotine metabolism biomarker in African American smokers: impact of chromosome 19 genetic influences

Chenoweth, M. J., Ware, J. J., Zhu, A. Z. X., Cole, C. B., Cox, L. S., Nollen, N., Ahluwalia, J. S., Benowitz, N. L., Schnoll, R. A., Hawk, L. W., Cinciripini, P. M., George, T. P., Lerman, C., Knight, J., Tyndale, R. F. & PGRN-PNAT Research Group, 03/2018, In: Addiction. 113, 3, p. 509-523 15 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights

Schizophrenia Working Group of the Psychiatric Genomics Consortium, 04/2018, In: Nature Genetics. 50, 4, p. 538-548 11 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Connected Health Cities – Lancaster – the north west coast and beyond

Knight, J. & King, N. S., 23/04/2018, In: Morecambe Bay Medical Journal. 7, 12, p. 310-310 1 p.

Research output: Contribution to Journal/Magazine › Journal article

A molecule-based genetic association approach implicates a range of voltage-gated calcium channels associated with schizophrenia

Schizophrenia Working Group of the Psychiatric Genomics Consortium, 06/2018, In: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics . 177, 4, p. 454-467 14 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Estimation of Genetic Correlation via Linkage Disequilibrium Score Regression and Genomic Restricted Maximum Likelihood

Schizophrenia Working Group of the Psychiatric Genomics Consortium, 7/06/2018, In: American Journal of Human Genetics. 102, 6, p. 1185-1194 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium, 14/06/2018, In: Cell. 173, 7, p. 1705-1715.e16 11 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Age at first birth in women is genetically associated with increased risk of schizophrenia

Schizophrenia Working Group of the Psychiatric Genomics Consortium, 5/07/2018, In: Scientific Reports. 8, 1, 14 p., 10168.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

APOE-ε4 associates with hippocampal volume, learning, and memory across the spectrum of Alzheimer's disease and dementia with Lewy bodies

Saeed, U., Mirza, S. S., MacIntosh, B. J., Herrmann, N., Keith, J., Ramirez, J., Nestor, S. M., Yu, Q., Knight, J., Swardfager, W., Potkin, S. G., Rogaeva, E., George-Hyslop, P. S., Black, S. E. & Masellis, M., 09/2018, In: Alzheimer's and Dementia. 14, 9, p. 1137-1147 11 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Heritability estimates of cortical anatomy: The influence and reliability of different estimation strategies

Patel, S., Patel, R., Park, M. T. M., Masellis, M., Knight, J. & Chakravarty, M. M., 09/2018, In: NeuroImage. 178, p. 78-91 14 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

Evangelou, E., Warren, H. R., Mosen-Ansorena, D., Mifsud, B., Pazoki, R., Gao, H., Ntritsos, G., Dimou, N., Cabrera, C. P., Karaman, I., Ng, F. L., Evangelou, M., Witkowska, K., Tzanis, E., Hellwege, J. N., Giri, A., Velez Edwards, D. R., Sun, Y. V., Cho, K., Gaziano, J. M., & 31 othersWilson, P. W. F., Tsao, P. S., Kovesdy, C. P., Esko, T., Mägi, R., Milani, L., Almgren, P., Boutin, T., Debette, S., Ding, J., Giulianini, F., Holliday, E. G., Jackson, A. U., Li-Gao, R., Lin, W-Y., Luan, J., Mangino, M., Oldmeadow, C., Prins, B. P., Qian, Y., Sargurupremraj, M., Shah, N., Surendran, P., Thériault, S., Verweij, N., Willems, S. M., Zhao, J-H., Amouyel, P., Connell, J., Knight, J. & Million Veteran Program, 17/09/2018, In: Nature Genetics. 20 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis

UK NIHR BioResource Rare Diseases Consortium, UK PAH Cohort Study Consortium, US PAH Biobank Consortium, Rhodes, C. J., Batai, K., Bleda, M., Haimel, M., Southgate, L., Germain, M., Pauciulo, M. W., Hadinnapola, C., Aman, J., Girerd, B., Arora, A., Knight, J., Hanscombe, K. B., Karnes, J. H., Kaakinen, M., Gall, H., Ulrich, A., & 33 othersHarbaum, L., Cebola, I., Ferrer, J., Lutz, K., Swietlik, E. M., Ahmad, F., Amouyel, P., Archer, S. L., Argula, R., Austin, E. D., Badesch, D., Bakshi, S., Barnett, C., Benza, R., Bhatt, N., Bogaard, H. J., Burger, C. D., Chakinala, M., Church, C., Coghlan, J. G., Condliffe, R., Corris, P. A., Danesino, C., Debette, S., Elliott, C. G., Elwing, J., Eyries, M., Fortin, T., Franke, A., Frantz, R. P., Frost, A., Garcia, J. G. N. & Ghio, S., 1/03/2019, In: Lancet Respiratory Medicine. 7, 3, p. 227-238 12 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

CommonMind Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium & iPSYCH-GEMS Schizophrenia Working Group, 1/04/2019, In: Nature Genetics. 51, 4, p. 659-674 16 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia

Wellcome Trust Case Control Consortium 2 & Schizophrenia Working Group of the Psychiatric Genomics Consortium, 1/04/2019, In: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics . 180, 3, p. 223-231 9 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores

M.R.C.Psych & Schizophrenia Working Group of the Psychiatric Genomics Consortium, 1/08/2019, In: American Journal of Psychiatry. 176, 8, p. 651-660 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

The role of polygenic risk score gene-set analysis in the context of the omnigenic model of schizophrenia

Schizophrenia Working Group of the Psychiatric Genomics Consortium 2, 1/08/2019, In: Neuropsychopharmacology. 44, 9, p. 1562-1569 8 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A polygenic resilience score moderates the genetic risk for schizophrenia

Schizophrenia Working Group of the Psychiatric Genomics Consortium, 6/09/2019, In: Molecular Psychiatry. 2019, 16 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Cross-disorder analysis of schizophrenia and 19 immune-mediated diseases identifies shared genetic risk

Pouget, J. G., Han, B., Wu, Y., Mignot, E., Ollila, H. M., Barker, J., Spain, S., Dand, N., Trembath, R., Martin, J., Mayes, M. D., Bossini-Castillo, L., López-Isac, E., Jin, Y., Santorico, S. A., Spritz, R. A., Hakonarson, H., Polychronakos, C., Raychaudhuri, S., Knight, J., & 1 othersSchizophrenia Working Group of the Psychiatric Genomics Consortium, 15/10/2019, In: Human Molecular Genetics. 28, 20, p. 3498-3513 16 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

APOE-ɛ4, white matter hyperintensities, and cognition in Alzheimer and Lewy body dementia

Saeed Mirza, S., Saeed, U., Knight, J., Ramirez, J., Stuss, D., Keith, J., Nestor, S. M., Yu, D., Swardfager, W., Rogaeva, E., George-Hyslop, P. S., Black, S. E. & Masellis, M., 5/11/2019, In: Neurology. 93, 19, p. e1807-e1819 13 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Can we accurately classify schizophrenia patients from healthy controls using magnetic resonance imaging and machine learning? A multi-method and multi-dataset study

Winterburn, J. L., Voineskos, A. N., Devenyi, G. A., Plitman, E., de la Fuente-Sandoval, C., Bhagwat, N., Graff-Guerrero, A., Knight, J. & Chakravarty, M. M., 1/12/2019, In: Schizophrenia Research. 214, p. 3-10 8 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Cross-Disorder Group of the Psychiatric Genomics Consortium. Electronic address: plee0@mgh.harvard.edu, 12/12/2019, In: Cell. 179, 7, p. 1469-1482.e11 14 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Genetic correlations of psychiatric traits with body composition and glycemic traits are sex- and age-dependent

ADHD Working Group of the Psychiatric Genomics Consortium, 18/12/2019, In: Nature Communications. 10, 1, 12 p., 5765.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Comparative genetic architectures of schizophrenia in East Asian and European populations

Schizophrenia Working Group of the Psychiatric Genomics Consortium, 31/12/2019, In: Nature Genetics. 51, 12, p. 1670-1678 9 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

The Relationship Between Polygenic Risk Scores and Cognition in Schizophrenia

GROUP Investigators & Schizophrenia Working Group of the Psychiatric Genomics Consortium, 1/03/2020, In: Schizophrenia Bulletin. 46, 2, p. 336-344 9 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Complement genes contribute sex-biased vulnerability in diverse disorders

Schizophrenia Working Group of the Psychiatric Genomics Consortium 2, 11/05/2020, (E-pub ahead of print) In: Nature. 28 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

COVID-19 exposes the urgent need for coding of outpatient neurology episodes

Kemp, M., Biggin, F., Dayanandan, R., Knight, J. & Emsley, H. C. A., 31/08/2020, In: BMJ Neurology Open. 2, 2, 2 p., e000080.

Research output: Contribution to Journal/Magazine › Editorial › peer-review

Routinely collected patient data in neurology research: a systematic mapping review

Biggin, F., Emsley, H. & Knight, J., 27/11/2020, In: BMC Neurology. 20, 9 p., 431.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A modelling framework for developing early warning systems of COPD emergency admissions

Johnson, O., Knight, J. & Giorgi, E., 1/02/2021, In: Spatial and Spatio-temporal Epidemiology. 36, 9 p., 100392.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Late-onset epilepsy predicts stroke: Systematic review and meta-analysis

Wall, J., Knight, J. & Emsley, H. C. A., 1/02/2021, In: Epilepsy and Behavior. 115, 6 p., 107634.

Research output: Contribution to Journal/Magazine › Review article › peer-review

Variation in waiting times by diagnostic category: an observational study of 1,951 referrals to a neurology outpatient clinic

Biggin, F., Howcroft, T., Davies, Q., Knight, J. & Emsley, H., 31/05/2021, In: BMJ Neurology Open. 3, 1, 8 p., 000133.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Problematising Characteristicness: A Biomedical Association Case Study

Prentice, S., Knight, J., Rayson, P., El-Haj, M. & Rutherford, N., 31/08/2021, In: International Journal of Corpus Linguistics. 26, 3, p. 305-335 31 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Analyses of nicotine metabolism biomarker genetics stratified by sex in African and European Americans

Chenoweth, M. J., Cox, L. S., Nollen, N. L., Ahluwalia, J. S., Benowitz, N. L., Lerman, C., Knight, J. & Tyndale, R. F., 1/10/2021, In: Scientific Reports. 11, 1, 12 p., 19572.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A genome-wide association study of nausea incidence in varenicline-treated cigarette smokers

Chenoweth, M. J., Lerman, C., Knight, J. & Tyndale, R. F., 31/10/2021, In: Nicotine and Tobacco Research. 23, 10, p. 1805-1809 5 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Transferability Of Ancestry-Specific And Cross-Ancestry CYP2A6 Activity Genetic Risk Scores In African And European Populations

El-Boraie, A., Chenoweth, M. J., Pouget, J. G., Benowitz, N. L., Fukunaga, K., Mushiroda, T., Kubo, M., Nollen, N. L., Cox, L. S., Lerman, C., Knight, J. & Tyndale, R. F., 31/10/2021, In: Clinical pharmacology and therapeutics. 110, 4, p. 975-985 11 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Are child health information services a viable source of accurate vaccination data for clinicians working in paediatric emergency departments in England?

Isba, R., Davies, N. & Knight, J., 31/12/2021, In: BMJ Health Care and Informatics. 28, 1, 3 p., e100486.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Accuracy and applications of sequencing and genotyping approaches for CYP2A6 and homologous genes

Langlois, A. W. R., El-Boraie, A., Fukunaga, K., Mushiroda, T., Kubo, M., Lerman, C., Knight, J., Scherer, S. E., Chenoweth, M. J. & Tyndale, R. F., 30/06/2022, In: Pharmacogenetics and genomics. 32, 4, p. 159-172 14 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Does sex alter the relationship between CYP2B6 variation, hydroxybupropion concentration and bupropion-aided smoking cessation in African Americans? A moderated mediation analysis

Chenoweth, M. J., Peng, A. R., Zhu, A. Z. X., Cox, L. S., Nollen, N. L., Ahluwalia, J. S., Benowitz, N. L., Knight, J., Swardfager, W. & Tyndale, R. F., 30/06/2022, In: Addiction. 117, 6, p. 1715-1724 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

A Domain Based Approach to Semantic Lexicon Expansion

Prentice, S., Rayson, P., Knight, J., El-Haj, M. & Elstein, S., 30/09/2022, In: International Journal of Lexicography. 35, 3, p. 364-377 14 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Numbers and types of neurological emergencies in England and the influence of socioeconomic deprivation: a retrospective analysis of hospital episode statistics data

Jackson, M., Szczepaniak, M., Wall, J., Maskery, M., Mummery, C., Morrish, P., Williams, A., Knight, J. & Emsley, H. C. A., 4/11/2022, In: BMJ Open. 12, 11, 7 p., e061843.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Impact of digital technology in care homes on Emergency Department attendances

Garner, A., Knight, J., Preston, N., Dixon, S., Watchorn, S., Caiado, C., McShane, C., King, G. & Mason, S., 22/11/2022, In: Emergency Medicine Journal. 39, 12, 1 p., A974.

Research output: Contribution to Journal/Magazine › Meeting abstract

Measles, mumps, and rubella vaccination coverage in children younger than 5 years attending a paediatric emergency department in Manchester, UK: a cross-sectional observational study

Isba, R., Brennan, L., Davies, N. & Knight, J., 25/11/2022, In: The Lancet. 400 , Suppl 1, p. S51 1 p.

Research output: Contribution to Journal/Magazine › Meeting abstract › peer-review

Influence of CYP2A6 genetic variation, nicotine dependence severity, and treatment on smoking cessation success

Chenoweth, M. J., Lerman, C., Knight, J. & Tyndale, R. F., 1/06/2023, In: Nicotine and Tobacco Research. 25, 6, p. 1207-1211 5 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Unmet vaccination need among children under the age of five attending the paediatric emergency department: a cross-sectional study in a large UK district general hospital

Isba, R., Brennan, L., Egboko, F., Edge, R., Davies, N. & Knight, J., 27/06/2023, In: BMJ Open. 13, 6, e072053.

Research output: Contribution to Journal/Magazine › Journal article › peer-review