1990-2000: progress in determining high blood pressure genes

Munroe, P. B., Knight, J. & Caulfield, M. J., 05/2000, In: Annals of the Academy of Medicine, Singapore. 29, 3, p. 357-363 7 p.

Research output: Contribution to journal › Journal article › peer-review

A Bayesian method to incorporate hundreds of functional characteristics with association evidence to improve variant prioritization

Gagliano, S. A., Barnes, M. R., Weale, M. E. & Knight, J., 20/05/2014, In: PLoS ONE. 9, 5, 14 p., e98122.

Research output: Contribution to journal › Journal article › peer-review

A central resource for accurate allele frequency estimation from pooled DNA genotyped on DNA microarrays

Simpson, C. L., Knight, J., Butcher, L. M., Hansen, V. K., Meaburn, E., Schalkwyk, L. C., Craig, I. W., Powell, J. F., Sham, P. C. & Al-Chalabi, A., 2005, In: Nucleic Acids Research. 33, 3, e25.

Research output: Contribution to journal › Journal article › peer-review

A common haplotype of the dopamine transporter gene associated with attention-deficit/hyperactivity disorder and interacting with maternal use of alcohol during pregnancy

Brookes, K-J., Mill, J., Guindalini, C., Curran, S., Xu, X., Knight, J., Chen, C-K., Huang, Y-S., Sethna, V., Taylor, E., Chen, W., Breen, G. & Asherson, P., 01/2006, In: Archives of General Psychiatry. 63, 1, p. 74-81 8 p.

Research output: Contribution to journal › Journal article › peer-review

A comparison of association statistics between pooled and individual genotypes

Knight, J., Saccone, S. F., Zhang, Z., Ballinger, D. G. & Rice, J. P., 03/2009, In: Human Heredity. 67, 4, p. 219-225 7 p.

Research output: Contribution to journal › Journal article › peer-review

A Domain Based Approach to Semantic Lexicon Expansion

Prentice, S., Rayson, P., Knight, J., El-Haj, M. & Elstein, S., 4/12/2021, (E-pub ahead of print) In: International Journal of Lexicography. 16 p.

Research output: Contribution to journal › Journal article › peer-review

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1

Strange, A., Capon, F., Spencer, C. C. A., Knight, J., Weale, M. E., Allen, M. H., Barton, A., Band, G., Bellenguez, C., Bergboer, J. G. M., Blackwell, J. M., Bramon, E., Bumpstead, S. J., Casas, J. P., Cork, M. J., Corvin, A., Deloukas, P., Dilthey, A., Duncanson, A., Edkins, S. & 31 others, Estivill, X., Fitzgerald, O., Freeman, C., Giardina, E., Gray, E., Hofer, A., Hüffmeier, U., Hunt, S. E., Irvine, A. D., Jankowski, J., Kirby, B., Langford, C., Lascorz, J., Leman, J., Leslie, S., Mallbris, L., Markus, H. S., Mathew, C. G., McLean, W. H. I., McManus, R., Mössner, R., Moutsianas, L., Naluai, A. T., Nestle, F. O., Novelli, G., Onoufriadis, A., Palmer, C. N. A., Perricone, C., Pirinen, M., Plomin, R. & Genetic Analysis of Psoriasis Consortium & the Wellcome Trust Case Control Consortium 2, 11/2010, In: Nature Genetics. 42, 11, p. 985-990 6 p.

Research output: Contribution to journal › Letter › peer-review

A genome-wide association study of nausea incidence in varenicline-treated cigarette smokers

Chenoweth, M. J., Lerman, C., Knight, J. & Tyndale, R. F., 31/10/2021, In: Nicotine and Tobacco Research. 23, 10, p. 1805-1809 5 p.

Research output: Contribution to journal › Journal article › peer-review

A genome-wide association study of suicide severity scores in bipolar disorder

Zai, C. C., Gonçalves, V. F., Tiwari, A. K., Gagliano, S. A., Hosang, G., de Luca, V., Shaikh, S. A., King, N., Chen, Q., Xu, W., Strauss, J., Breen, G., Lewis, C. M., Farmer, A. E., McGuffin, P., Knight, J., Vincent, J. B. & Kennedy, J. L., 06/2015, In: Journal of Psychiatric Research. 65, p. 23-29 7 p.

Research output: Contribution to journal › Journal article › peer-review

A genome-wide significant linkage for severe depression on chromosome 3: the depression network study

Breen, G., Webb, B. T., Butler, A. W., van den Oord, E. J. C. G., Tozzi, F., Craddock, N., Gill, M., Korszun, A., Maier, W., Middleton, L., Mors, O., Owen, M. J., Cohen-Woods, S., Perry, J., Galwey, N. W., Upmanyu, R., Craig, I., Lewis, C. M., Ng, M., Brewster, S. & 8 others, Preisig, M., Rietschel, M., Jones, L., Knight, J., Rice, J., Muglia, P., Farmer, A. E. & McGuffin, P., 08/2011, In: American Journal of Psychiatry. 168, 8, p. 840-847 8 p.

Research output: Contribution to journal › Journal article › peer-review

A modelling framework for developing early warning systems of COPD emergency admissions

Johnson, O., Knight, J. & Giorgi, E., 1/02/2021, In: Spatial and Spatio-temporal Epidemiology. 36, 9 p., 100392.

Research output: Contribution to journal › Journal article › peer-review

A molecule-based genetic association approach implicates a range of voltage-gated calcium channels associated with schizophrenia

Schizophrenia Working Group of the Psychiatric Genomics Consortium, 06/2018, In: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics . 177, 4, p. 454-467 14 p.

Research output: Contribution to journal › Journal article › peer-review

A new method of linkage analysis using LOD scores for quantitative traits supports linkage of monoamine oxidase activity to D17S250 in the Collaborative Study on the Genetics of Alcoholism pedigrees

Curtis, D., Knight, J. & Sham, P. C., 09/2005, In: Psychiatric Genetics. 15, 3, p. 181-187 7 p.

Research output: Contribution to journal › Journal article › peer-review

A polygenic resilience score moderates the genetic risk for schizophrenia

Schizophrenia Working Group of the Psychiatric Genomics Consortium, 6/09/2019, In: Molecular Psychiatry. 2019, 16 p.

Research output: Contribution to journal › Journal article › peer-review

A pragmatic suggestion for dealing with results for candidate genes obtained from genome wide association studies

Curtis, D., Vine, A. E. & Knight, J., 10/05/2007, In: Genetics. 8, 6 p., 20.

Research output: Contribution to journal › Journal article › peer-review

A simple method for assessing the strength of evidence for association at the level of the whole gene

Curtis, D., Vine, A. E. & Knight, J., 17/11/2008, In: Advances and Applications in Bioinformatics and Chemistry : AABC. 1, p. 115-120 6 p.

Research output: Contribution to journal › Journal article › peer-review

A survey of current software for genetic power calculations

Knight, J., 2/03/2004, In: BMC Genomics. 1, 3, p. 225-227 3 p.

Research output: Contribution to journal › Journal article › peer-review

Accuracy and applications of sequencing and genotyping approaches for CYP2A6 and homologous genes

Langlois, A. W. R., El-Boraie, A., Fukunaga, K., Mushiroda, T., Kubo, M., Lerman, C., Knight, J., Scherer, S. E., Chenoweth, M. J. & Tyndale, R. F., 30/06/2022, In: Pharmacogenetics and genomics. 32, 4, p. 159-172 14 p.

Research output: Contribution to journal › Journal article › peer-review

Addiction-related genes in gambling disorders: new insights from parallel human and pre-clinical models

Lobo, D. S. S., Aleksandrova, L., Knight, J., Casey, D. M., el-Guebaly, N., Nobrega, J. N. & Kennedy, J. L., 08/2015, In: Molecular Psychiatry. 20, 8, p. 1002-1010 9 p.

Research output: Contribution to journal › Journal article › peer-review

Age at first birth in women is genetically associated with increased risk of schizophrenia

Schizophrenia Working Group of the Psychiatric Genomics Consortium, 5/07/2018, In: Scientific Reports. 8, 1, 14 p., 10168.

Research output: Contribution to journal › Journal article › peer-review

Age at onset in sod1-mediated amyotrophic lateral sclerosis shows familiality

Fogh, I., Rijsdijk, F., Andersen, P. M., Sham, P. C., Knight, J., Neale, B., McKenna-Yasek, D., Silani, V., Brown, R. H., Powell, J. F. & Al-Chalabi, A., 08/2007, In: Neurogenetics. 8, 3, p. 235-236 2 p.

Research output: Contribution to journal › Letter › peer-review

Allele-skewed DNA modification in the brain: relevance to a schizophrenia GWAS

Gagliano, S. A., Ptak, C., Mak, D. Y. F., Shamsi, M., Oh, G., Knight, J., Boutros, P. C. & Petronis, A., 5/05/2016, In: American Journal of Human Genetics. 98, 5, p. 956-962 7 p.

Research output: Contribution to journal › Journal article › peer-review

An investigation of candidate regions for association with bipolar disorder

Knight, J., Rochberg, N. S., Saccone, S. F., Nurnberger, J. I., Rice, J. P. & NIMH Genetics Initiative Bipolar Disorder Consortium, 5/10/2010, In: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics . 153B, 7, p. 1292-1297 6 p.

Research output: Contribution to journal › Journal article › peer-review

Analyses of nicotine metabolism biomarker genetics stratified by sex in African and European Americans

Chenoweth, M. J., Cox, L. S., Nollen, N. L., Ahluwalia, J. S., Benowitz, N. L., Lerman, C., Knight, J. & Tyndale, R. F., 1/10/2021, In: Scientific Reports. 11, 1, 12 p., 19572.

Research output: Contribution to journal › Journal article › peer-review

Analyzing the Role of MicroRNAs in Schizophrenia in the Context of Common Genetic Risk Variants

Schizophrenia Working Group of the Psychiatric Genomics Consortium, 04/2016, In: JAMA Psychiatry. 73, 4, p. 369-377 9 p.

Research output: Contribution to journal › Journal article › peer-review

APOE-ɛ4, white matter hyperintensities, and cognition in Alzheimer and Lewy body dementia

Saeed Mirza, S., Saeed, U., Knight, J., Ramirez, J., Stuss, D., Keith, J., Nestor, S. M., Yu, D., Swardfager, W., Rogaeva, E., George-Hyslop, P. S., Black, S. E. & Masellis, M., 5/11/2019, In: Neurology. 93, 19, p. e1807-e1819 13 p.

Research output: Contribution to journal › Journal article › peer-review

APOE-ε4 associates with hippocampal volume, learning, and memory across the spectrum of Alzheimer's disease and dementia with Lewy bodies

Saeed, U., Mirza, S. S., MacIntosh, B. J., Herrmann, N., Keith, J., Ramirez, J., Nestor, S. M., Yu, Q., Knight, J., Swardfager, W., Potkin, S. G., Rogaeva, E., George-Hyslop, P. S., Black, S. E. & Masellis, M., 09/2018, In: Alzheimer's and Dementia. 14, 9, p. 1137-1147 11 p.

Research output: Contribution to journal › Journal article › peer-review

Application of multi-locus analytical methods to identify interacting loci in case-control studies

Vermeulen, S. H. H. M., Den Heijer, M., Sham, P. C. & Knight, J., 09/2007, In: Annals of Human Genetics. 71, 5, p. 689-700 12 p.

Research output: Contribution to journal › Journal article › peer-review

Are child health information services a viable source of accurate vaccination data for clinicians working in paediatric emergency departments in England?

Isba, R., Davies, N. & Knight, J., 31/12/2021, In: BMJ health & care informatics. 28, 1, 3 p., e100486.

Research output: Contribution to journal › Journal article › peer-review

Assessing models for genetic prediction of complex traits: a comparison of visualization and quantitative methods

Gagliano, S. A., Paterson, A. D., Weale, M. E. & Knight, J., 22/05/2015, In: BMC Genomics. 16, 11 p., 405.

Research output: Contribution to journal › Journal article › peer-review

Association of the serotonin transporter gene, neuroticism and smoking behaviours

O'Gara, C., Knight, J., Stapleton, J., Luty, J., Neale, B., Nash, M., Heuzo-Diaz, P., Hoda, F., Cohen, S., Sutherland, G., Collier, D., Sham, P., Ball, D., McGuffin, P. & Craig, I., 2008, In: Journal of Human Genetics . 53, 3, p. 239-246 8 p.

Research output: Contribution to journal › Journal article › peer-review

Attention-Deficit Hyperactivity Disorder in the post-genomic era

Asherson, P., Knight, J. & IMAGE Consortium, 07/2004, In: European Child and Adolescent Psychiatry. 13 , Suppl 1, p. I50-70 21 p.

Research output: Contribution to journal › Journal article › peer-review

Biological insights from 108 schizophrenia-associated genetic loci

Schizophrenia Working Group of the Psychiatric Genomics Consortium, 24/07/2014, In: Nature. 511, 7510, p. 421-427 7 p.

Research output: Contribution to journal › Journal article › peer-review

Can we accurately classify schizophrenia patients from healthy controls using magnetic resonance imaging and machine learning? A multi-method and multi-dataset study

Winterburn, J. L., Voineskos, A. N., Devenyi, G. A., Plitman, E., de la Fuente-Sandoval, C., Bhagwat, N., Graff-Guerrero, A., Knight, J. & Chakravarty, M. M., 1/12/2019, In: Schizophrenia Research. 214, p. 3-10 8 p.

Research output: Contribution to journal › Journal article › peer-review

CEREBRAL PERFUSION AS AN IMAGING BIOMARKER OF PRESYMPTOMATIC GENETIC FRONTOTEMPORAL DEMENTIA: PRELIMINARY RESULTS FROM THE GENETIC FRONTOTEMPORAL DEMENTIA INITIATIVE (GENFI)

Mutsaerts, H. J. M. M. & Knight, J., 07/2016, In: Alzheimer's and Dementia. 12, 7 Suppl., p. P409-P411 3 p.

Research output: Contribution to journal › Meeting abstract

CLUMPHAP: a simple tool for performing haplotype-based association analysis

Knight, J., Curtis, D. & Sham, P. C., 09/2008, In: Genetic Epidemiology. 32, 6, p. 539-545 7 p.

Research output: Contribution to journal › Journal article › peer-review

Common variants in DGKK are strongly associated with risk of hypospadias

van der Zanden, L. F. M., van Rooij, I. A. L. M., Feitz, W. F. J., Knight, J., Donders, A. R. T., Renkema, K. Y., Bongers, E. M. H. F., Vermeulen, S. H. H. M., Kiemeney, L. A. L. M., Veltman, J. A., Arias-Vásquez, A., Zhang, X., Markljung, E., Qiao, L., Baskin, L. S., Nordenskjöld, A., Roeleveld, N., Franke, B. & Knoers, N. V. A. M., 01/2011, In: Nature Genetics. 43, 1, p. 48-50 3 p.

Research output: Contribution to journal › Letter › peer-review

Comparative genetic architectures of schizophrenia in East Asian and European populations

Schizophrenia Working Group of the Psychiatric Genomics Consortium, 31/12/2019, In: Nature Genetics. 51, 12, p. 1670-1678 9 p.

Research output: Contribution to journal › Journal article › peer-review

Complement genes contribute sex-biased vulnerability in diverse disorders

Schizophrenia Working Group of the Psychiatric Genomics Consortium 2, 11/05/2020, (E-pub ahead of print) In: Nature. 28 p.

Research output: Contribution to journal › Journal article › peer-review

Complex host genetics influence the microbiome in inflammatory bowel disease

Knights, D., Silverberg, M. S., Weersma, R. K., Gevers, D., Dijkstra, G., Huang, H., Tyler, A. D., van Sommeren, S., Imhann, F., Stempak, J. M., Huang, H., Vangay, P., Al-Ghalith, G. A., Russell, C., Sauk, J., Knight, J., Daly, M. J., Huttenhower, C. & Xavier, R. J., 2/12/2014, In: Genome Biology. 6, 12, 11 p., 107.

Research output: Contribution to journal › Journal article › peer-review

Conditional analysis identifies three novel major histocompatibility complex loci associated with psoriasis

Knight, J., Spain, S. L., Capon, F., Hayday, A., Nestle, F. O., Clop, A., Barker, J. N. W. N., Weale, M. E., Trembath, R. C. & Wellcome Trust Case Control Consortium, 1/12/2012, In: Human Molecular Genetics. 21, 23, p. 5185-5192 8 p.

Research output: Contribution to journal › Journal article › peer-review

Connected Health Cities – Lancaster – the north west coast and beyond

Knight, J. & King, N. S., 23/04/2018, In: Morecambe Bay Medical Journal. 7, 12, p. 310-310 1 p.

Research output: Contribution to journal › Journal article

Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis

Schizophrenia Working Group of Psychiatric Genomics Consortium, 12/2015, In: Nature Genetics. 47, 12, p. 1385-1392 8 p.

Research output: Contribution to journal › Journal article › peer-review

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

CNV and Schizophrenia Working Groups of the Psychiatric Genomics Consortium, 01/2017, In: Nature Genetics. 49, p. 27-35 9 p.

Research output: Contribution to journal › Journal article › peer-review

COVID-19 exposes the urgent need for coding of outpatient neurology episodes

Kemp, M., Biggin, F., Dayanandan, R., Knight, J. & Emsley, H. C. A., 31/08/2020, In: BMJ Neurology Open. 2, 2, 2 p., e000080.

Research output: Contribution to journal › Editorial › peer-review

Cross-disorder analysis of schizophrenia and 19 immune-mediated diseases identifies shared genetic risk

Pouget, J. G., Han, B., Wu, Y., Mignot, E., Ollila, H. M., Barker, J., Spain, S., Dand, N., Trembath, R., Martin, J., Mayes, M. D., Bossini-Castillo, L., López-Isac, E., Jin, Y., Santorico, S. A., Spritz, R. A., Hakonarson, H., Polychronakos, C., Raychaudhuri, S., Knight, J. & 1 others, Schizophrenia Working Group of the Psychiatric Genomics Consortium, 15/10/2019, In: Human Molecular Genetics. 28, 20, p. 3498-3513 16 p.

Research output: Contribution to journal › Journal article › peer-review

CYP2A6 reduced activity gene variants confer reduction in lung cancer risk in African American smokers: findings from two independent populations

Wassenaar, C. A., Ye, Y., Cai, Q., Aldrich, M. C., Knight, J., Spitz, M. R., Wu, X., Blot, W. J. & Tyndale, R. F., 01/2015, In: Carcinogenesis. 36, 1, p. 99-103 5 p.

Research output: Contribution to journal › Journal article › peer-review

Depression Case Control (DeCC) study fails to support involvement of the muscarinic acetylcholine receptor M2 (CHRM2) gene in recurrent major depressive disorder

Cohen-Woods, S., Gaysina, D., Craddock, N., Farmer, A., Gray, J., Gunasinghe, C., Hoda, F., Jones, L., Knight, J., Korszun, A., Owen, M. J., Sterne, A., Craig, I. W. & McGuffin, P., 15/04/2009, In: Human Molecular Genetics. 18, 8, p. 1504-1509 6 p.

Research output: Contribution to journal › Journal article › peer-review

Design and analysis of association studies using pooled DNA from large twin samples

Knight, J. & Sham, P., 09/2006, In: Behavior Genetics. 36, 5, p. 665-677 13 p.

Research output: Contribution to journal › Journal article › peer-review