Home > Research > Publications & Outputs > Observation of "remote knock-on", a new permeat...

Associated organisational unit

Electronic data


Text available via DOI:

View graph of relations

Observation of "remote knock-on", a new permeation-enhancement mechanism in ion channels

Research output: Contribution to journalMeeting abstractpeer-review

<mark>Journal publication date</mark>28/01/2014
<mark>Journal</mark>Biophysical Journal
Issue number2 Suppl. 1
Number of pages1
Pages (from-to)133A
Publication StatusPublished
<mark>Original language</mark>English
Event58th Annual Meeting of the Biophysical-Society - San Francisco, Canada
Duration: 15/02/201419/02/2014


Conference58th Annual Meeting of the Biophysical-Society


We report observation of a novel ‘‘remote knock-on’’ mechanism for enhancement of permeation in Brownian dynamics simulations of a simple model ion channel. Unlike conventional knock-on, which requires a second ion of the same species to enter the channel in order to knock forward and replace an ion already in the channel, the new mechanism does not require the instigating ion to enter the channel, nor that it be of the same species.