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Research output: Contribution to Journal/Magazine › Meeting abstract › peer-review
Research output: Contribution to Journal/Magazine › Meeting abstract › peer-review
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TY - JOUR
T1 - Observation of "remote knock-on", a new permeation-enhancement mechanism in ion channels
AU - Luchinsky, Dmitrii G.
AU - Tindjong, Rodrigue
AU - Kaufman, Igor
AU - McClintock, Peter V. E.
AU - Khovanov, Igor A.
AU - Eisenberg, Bob S.
PY - 2014/1/28
Y1 - 2014/1/28
N2 - We report observation of a novel ‘‘remote knock-on’’ mechanism for enhancement of permeation in Brownian dynamics simulations of a simple model ion channel. Unlike conventional knock-on, which requires a second ion of the same species to enter the channel in order to knock forward and replace an ion already in the channel, the new mechanism does not require the instigating ion to enter the channel, nor that it be of the same species.
AB - We report observation of a novel ‘‘remote knock-on’’ mechanism for enhancement of permeation in Brownian dynamics simulations of a simple model ion channel. Unlike conventional knock-on, which requires a second ion of the same species to enter the channel in order to knock forward and replace an ion already in the channel, the new mechanism does not require the instigating ion to enter the channel, nor that it be of the same species.
U2 - 10.1016/j.bpj.2013.11.783
DO - 10.1016/j.bpj.2013.11.783
M3 - Meeting abstract
VL - 106
SP - 133A
JO - Biophysical Journal
JF - Biophysical Journal
SN - 0006-3495
IS - 2 Suppl. 1
T2 - 58th Annual Meeting of the Biophysical-Society
Y2 - 15 February 2014 through 19 February 2014
ER -