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The effects of prenatal HIV exposure on language functioning in Kenyan children: establishing an evaluative framework

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Article number463
<mark>Journal publication date</mark>12/10/2016
<mark>Journal</mark>BMC Research Notes
Issue number1
Number of pages6
Publication StatusPublished
<mark>Original language</mark>English


HIV infection has been associated with impaired language development in prenatally exposed children. Although most of the burden of HIV occurs in sub-Saharan Africa, there have not been any comprehensive studies of HIV exposure on multiple aspects of language development using instruments appropriate for the population.

We compared language development in children exposed to HIV in utero to community controls (N = 262, 8–30 months) in rural Kenya, using locally adapted and validated communicative development inventories.

The mean score of the younger HIV-exposed uninfected infants (8–15 months) was not significantly below that of the controls; however older HIV-exposed uninfected children had significantly poorer language scores, with HIV positive children scoring more poorly than community controls, on several measures.

Our preliminary data indicates that HIV infection is associated with impaired early language development, and that the methodology developed would be responsive to a more detailed investigation of the variability in outcome amongst children exposed to HIV, irrespective of their infection status.