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The effects of prenatal HIV exposure on language functioning in Kenyan children: establishing an evaluative framework

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The effects of prenatal HIV exposure on language functioning in Kenyan children: establishing an evaluative framework. / Alcock, K. J.; Ali, Amina; Newton, Charles R. et al.
In: BMC Research Notes, Vol. 9, No. 1, 463, 12.10.2016.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Alcock, KJ, Ali, A, Newton, CR & Holding, P 2016, 'The effects of prenatal HIV exposure on language functioning in Kenyan children: establishing an evaluative framework', BMC Research Notes, vol. 9, no. 1, 463. https://doi.org/10.1186/s13104-016-2264-3

APA

Alcock, K. J., Ali, A., Newton, C. R., & Holding, P. (2016). The effects of prenatal HIV exposure on language functioning in Kenyan children: establishing an evaluative framework. BMC Research Notes, 9(1), Article 463. https://doi.org/10.1186/s13104-016-2264-3

Vancouver

Alcock KJ, Ali A, Newton CR, Holding P. The effects of prenatal HIV exposure on language functioning in Kenyan children: establishing an evaluative framework. BMC Research Notes. 2016 Oct 12;9(1):463. doi: 10.1186/s13104-016-2264-3

Author

Alcock, K. J. ; Ali, Amina ; Newton, Charles R. et al. / The effects of prenatal HIV exposure on language functioning in Kenyan children : establishing an evaluative framework. In: BMC Research Notes. 2016 ; Vol. 9, No. 1.

Bibtex

@article{cd1c73bc224b481c8ee77387ae0158ba,
title = "The effects of prenatal HIV exposure on language functioning in Kenyan children: establishing an evaluative framework",
abstract = "BackgroundHIV infection has been associated with impaired language development in prenatally exposed children. Although most of the burden of HIV occurs in sub-Saharan Africa, there have not been any comprehensive studies of HIV exposure on multiple aspects of language development using instruments appropriate for the population.MethodsWe compared language development in children exposed to HIV in utero to community controls (N = 262, 8–30 months) in rural Kenya, using locally adapted and validated communicative development inventories.ResultsThe mean score of the younger HIV-exposed uninfected infants (8–15 months) was not significantly below that of the controls; however older HIV-exposed uninfected children had significantly poorer language scores, with HIV positive children scoring more poorly than community controls, on several measures.ConclusionsOur preliminary data indicates that HIV infection is associated with impaired early language development, and that the methodology developed would be responsive to a more detailed investigation of the variability in outcome amongst children exposed to HIV, irrespective of their infection status.",
keywords = "HIV , Language , Africa , Children",
author = "Alcock, {K. J.} and Amina Ali and Newton, {Charles R.} and Penny Holding",
year = "2016",
month = oct,
day = "12",
doi = "10.1186/s13104-016-2264-3",
language = "English",
volume = "9",
journal = "BMC Research Notes",
issn = "1756-0500",
publisher = "BioMed Central",
number = "1",

}

RIS

TY - JOUR

T1 - The effects of prenatal HIV exposure on language functioning in Kenyan children

T2 - establishing an evaluative framework

AU - Alcock, K. J.

AU - Ali, Amina

AU - Newton, Charles R.

AU - Holding, Penny

PY - 2016/10/12

Y1 - 2016/10/12

N2 - BackgroundHIV infection has been associated with impaired language development in prenatally exposed children. Although most of the burden of HIV occurs in sub-Saharan Africa, there have not been any comprehensive studies of HIV exposure on multiple aspects of language development using instruments appropriate for the population.MethodsWe compared language development in children exposed to HIV in utero to community controls (N = 262, 8–30 months) in rural Kenya, using locally adapted and validated communicative development inventories.ResultsThe mean score of the younger HIV-exposed uninfected infants (8–15 months) was not significantly below that of the controls; however older HIV-exposed uninfected children had significantly poorer language scores, with HIV positive children scoring more poorly than community controls, on several measures.ConclusionsOur preliminary data indicates that HIV infection is associated with impaired early language development, and that the methodology developed would be responsive to a more detailed investigation of the variability in outcome amongst children exposed to HIV, irrespective of their infection status.

AB - BackgroundHIV infection has been associated with impaired language development in prenatally exposed children. Although most of the burden of HIV occurs in sub-Saharan Africa, there have not been any comprehensive studies of HIV exposure on multiple aspects of language development using instruments appropriate for the population.MethodsWe compared language development in children exposed to HIV in utero to community controls (N = 262, 8–30 months) in rural Kenya, using locally adapted and validated communicative development inventories.ResultsThe mean score of the younger HIV-exposed uninfected infants (8–15 months) was not significantly below that of the controls; however older HIV-exposed uninfected children had significantly poorer language scores, with HIV positive children scoring more poorly than community controls, on several measures.ConclusionsOur preliminary data indicates that HIV infection is associated with impaired early language development, and that the methodology developed would be responsive to a more detailed investigation of the variability in outcome amongst children exposed to HIV, irrespective of their infection status.

KW - HIV

KW - Language

KW - Africa

KW - Children

U2 - 10.1186/s13104-016-2264-3

DO - 10.1186/s13104-016-2264-3

M3 - Journal article

VL - 9

JO - BMC Research Notes

JF - BMC Research Notes

SN - 1756-0500

IS - 1

M1 - 463

ER -