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Biomedical and Life Sciences

  1. 2020
  2. E-pub ahead of print

    Aggregation Kinetics and Filament Structure of a Tau Fragment Are Influenced by the Sulfation Pattern of the Cofactor Heparin

    Townsend, D., Fullwood, N., Yates, E. & Middleton, D., 21/09/2020, (E-pub ahead of print) In: Biochemistry.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  3. Published

    Challenges and Opportunities in Conducting and Applying Design Research beyond Global North to the Global South

    Tsekleves, E., Darby, A., Ahorlu, C., Pickup, R., de Souza, D. & Boakye, D., 15/09/2020, Proceedings of DRS 2020 International Conference: Synergy: Volume 3 Co-Creation. Boess, S., Cheung, M. & Cain, R. (eds.). Design Research Society, Vol. 3. p. 1336-1353 18 p. 145. (DRS 2020 Proceedings)(Proceedings of DRS 2020 International Conference; vol. 3).

    Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paperpeer-review

  4. Published

    Neurotrophin signaling in medulloblastoma

    Thomaz, A., Jaeger, M., Brunetto, A. L., Brunetto, A. T., Gregianin, L., de Farias, C. B., Ramaswamy, V., Nör, C., Taylor, M. D. & Roesler, R., 7/09/2020, In: Cancers. 12, 9, p. 1-22 22 p., 2542.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  5. Published

    Actions of cannabinoids on amoebae

    Al-Hammadi, I., 1/09/2020, Lancaster University. 175 p.

    Research output: ThesisDoctoral Thesis

  6. Published

    Artificial Intelligence-Assisted Loop Mediated Isothermal Amplification (ai-LAMP) for Rapid Detection of SARS-CoV-2

    Rohaim, M., Clayton, E., Sahin, I., Vilela, J., Khalifa, M., Al-Natour, M., Bayoumi, M., Poirier, A. C., Branavan, M., Tharmakulasingam, M., Choudhry, M. S., Sodi, R., Brown, A., Burkhart, P., Hacking, W., Botham, J., Boyce, J., Wilkinson, H., Williams, C. & Whittingham-Dowd, J. & 8 others, Shaw, E., Hodges, M., Butler, L., Bates, M., La Ragione, R., Balachandran, W., Fernando, A. & Munir, M., 1/09/2020, In: Viruses. 12, 9, 19 p., 972.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  7. Published

    Experimental infection of Leishmania (Mundinia) martiniquensis in BALB/c mice and Syrian golden hamsters

    Intakhan, N., Chanmol, W., Kongkaew, A., Somboon, P., Bates, M. D., Bates, P. A. & Jariyapan, N., 1/09/2020, In: Parasitology Research. 119, p. 3041-3051 11 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  8. Published

    Expression and pharmacological inhibition of TrkB and EGFR in glioblastoma

    Pinheiro, K. V., Thomaz, A., Souza, B. K., Metcalfe, V. A., Freire, N. H., Brunetto, A. T., de Farias, C. B., Jaeger, M., Bambini, V., Smith, C. G. S., Shaw, L. & Roesler, R., 1/09/2020, In: Molecular Biology Reports. 47, p. 6817–6828 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  9. Published

    Ionic Coulomb blockade and the determinants of selectivity in the NaChBac bacterial sodium channel

    Fedorenko, O. A., Kaufman, I. K., Gibby, W. A. T., Barabash, M. L., Luchinsky, D. G., Roberts, S. K. & McClintock, P. V. E., 1/09/2020, In: Biochimica et Biophysica Acta (BBA) - Biomembranes. 1862, 9, 9 p., 183301.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  10. Published

    A Scalable Topical Vectored Vaccine Candidate Against SARS-CoV-2

    Rohaim, M. A. & Munir, M., 24/08/2020, In: Vaccines. 8, 3, 16 p., 472.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  11. Published

    An analysis of preclinical efficacy testing of antivenoms for sub-Saharan Africa: Inadequate independent scrutiny and poor-quality reporting are barriers to improving snakebite treatment and management

    Ainsworth, S., Menzies, S. K., Casewell, N. R. & Harrison, R. A., 20/08/2020, In: PLoS Neglected Tropical Diseases. 14, 8, p. 1-25 25 p., e0008579.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  12. Published

    The effect of general anaesthetics on brain lactate release.

    Hadjihambi, A., Karagiannis, A., Theparambil, S., Gareth, L. A. P. F. F. F. & Gourine, A., 15/08/2020, In: European Journal of Pharmacology. 881, 173188.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  13. Published

    The proteasome controls ESCRT-III–mediated cell division in an archaeon

    Tarrason Risa, G., Hurtig, F., Bray, S., Hafner, A. E., Harker-Kirschneck, L., Faull, P., Davis, C., Papatziamou, D., Mutavchiev, D. R., Fan, C., Meneguello, L., Arashiro Pulschen, A., Dey, G., Culley, S., Kilkenny, M., Souza, D. P., Pellegrini, L., de Bruin, R. A. M., Henriques, R. & Snijders, A. P. & 4 others, Šarić, A., Lindås, A.-C., Robinson, N. P. & Baum, B., 7/08/2020, In: Science. 369, eaaz2532.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  14. Published

    Clearance of interstitial fluid (ISF) and CSF (CLIC) group—part of Vascular Professional Interest Area (PIA): Cerebrovascular disease and the failure of elimination of Amyloid-β from the brain and retina with age and Alzheimer's disease-Opportunities for Therapy

    Carare, R. O., Aldea, R., Agarwal, N., Bacskai, B. J., Bechman, I., Boche, D., Bu, G., Bulters, D., Clemens, A., Counts, S. E., de Leon, M., Eide, P. K., Fossati, S., Greenberg, S. M., Hamel, E., Hawkes, C. A., Koronyo-Hamaoui, M., Hainsworth, A. H., Holtzman, D. & Ihara, M. & 25 others, Jefferson, A., Kalaria, R. N., Kipps, C. M., Kanninen, K. M., Leinonen, V., McLaurin, J. A., Miners, S., Malm, T., Nicoll, J. A. R., Piazza, F., Paul, G., Rich, S. M., Saito, S., Shih, A., Scholtzova, H., Snyder, H., Snyder, P., Thormodsson, F. R., van Veluw, S. J., Weller, R. O., Werring, D. J., Wilcock, D., Wilson, M. R., Zlokovic, B. V. & Verma, A., 3/08/2020, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 12, 1, 7 p., e12053.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  15. Published

    Helminth Sensing at the Intestinal Epithelial Barrier—A Taste of Things to Come

    Faniyi, A. A., Wijanarko, K. J., Tollitt, J. & Worthington, J. J., 30/07/2020, In: Frontiers in Immunology. 11, 8 p., 1489.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  16. Published

    Drug-responsive autism phenotypes in the 16p11.2 deletion mouse model: a central role for gene-environment interactions

    Mitchell, E. J., Thomson, D. M., Openshaw, R. L., Bristow, G. C., Dawson, N., Pratt, J. A. & Morris, B. J., 23/07/2020, In: Scientific Reports. 10, 1, 11 p., 12303.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  17. Published

    Profiling cytotoxic microRNAs in pediatric and adult glioblastoma cells by high-content screening, identification, and validation of miR-1300

    Boissinot, M., King, H., Adams, M., Higgins, J., Shaw, G., Ward, T. A., Steele, L. P., Tams, D., Morton, R., Polson, E., Silva, B. D., Droop, A., Hayes, J. L., Martin, H., Laslo, P., Morrison, E., Tomlinson, D. C., Wurdak, H., Bond, J. & Lawler, S. E. & 1 others, Short, S. C., 23/07/2020, In: Oncogene. 39, 30, p. 5292-5306 15 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  18. Published

    Insulin/IGF-like signalling and brain ageing in Drosophila melanogaster

    Dravecz, N., 15/07/2020, Lancaster University. 284 p.

    Research output: ThesisDoctoral Thesis

  19. Published

    Mitogen-activated protein kinase phosphatase-2 deletion modifies ventral tegmental area function and connectivity and alters reward processing

    Pytka, K., Dawson, N., Tossell, K., Ungless, M. A., Plevin, R., Brett, R. R. & Bushell, T. J., 1/07/2020, In: European Journal of Neuroscience. 52, 2, p. 2838-2852 15 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  20. Published

    Dynamic Programming Algorithms Applied to Musical Counterpoint in Process Composition: An Example Using Henri Pousseur’s Scambi

    Cochrane, L. J. & Gatherer, D., 30/06/2020, In: Preprints. 12 p.

    Research output: Contribution to Journal/MagazineJournal article

  21. Published

    Modes of action of the archaeal Mre11/Rad50 DNA-repair complex revealed by fast-scan atomic force microscopy

    Zabolotnaya, E., Mela, I., Williamson, M., Bray, S., Yau, S. K., Papatziamou, D., Edwardson, J. M., Robinson, N. & Henderson, R., 30/06/2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 26, p. 14936-14947 12 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  22. Published

    Candida auris Phenotypic Heterogeneity Determines Pathogenicity In Vitro

    Brown, J. L., Delaney, C., Short, B., Butcher, M. C., McKloud, E., Williams, C., Kean, R. & Ramage, G., 24/06/2020, In: mSphere. 5, 3, 15 p., e00371-20.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  23. E-pub ahead of print

    Circular dichroism spectroscopy identifies the β-adrenoceptor agonist salbutamol as a direct inhibitor of tau filament formation in vitro.

    Middleton, D., Townsend, D., Hughes, E., Fullwood, N., Siligardi, G., Hussain, R. & Mala, B., 10/06/2020, (E-pub ahead of print) In: ACS Chemical Neuroscience.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  24. Published

    Diagnostic biomarkers for Alzheimer’s disease using non‐invasive specimens

    Paraskevaidi, M., Allsop, D., Karim, S., Martin, F. & Crean, S., 1/06/2020, In: Journal of Clinical Medicine. 9, 6, 19 p., 1673.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

  25. Published

    FALC stromal cells define a unique immunological niche for the surveillance of serous cavities

    Jackson-Jones, L. & Benezech, C., 1/06/2020, In: Current opinion in immunology. 64, p. 42-49 8 p.

    Research output: Contribution to Journal/MagazineReview articlepeer-review

  26. Published

    Photoprotection conferred by low level summer sunlight exposures against pro-inflammatory UVR insult

    Felton, S. J., Shih, B. B., Watson, R. E. B., Kift, R., Webb, A. R. & Rhodes, L. E., 1/06/2020, In: Photochemical and Photobiological Sciences. 19, 6, p. 810-818 9 p.

    Research output: Contribution to Journal/MagazineJournal articlepeer-review

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