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Biomedical and Life Sciences

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  1. Harnessing knowledge of lifespan biological, health, environmental and psychosocial mechanisms of cognitive frailty for integrated interventions

    Broughton, S. (Co-Investigator) & Holland, C. (Principal Investigator)

    14/02/22 → 31/03/25

    Project: Research

  2. Mechanisms of gut brain axis involvement in ectotherm thermotolerance: "how the gut brain axis helps animals weather the heat?"

    Benedetto, A. (Principal Investigator)

    BBSRC

    Project: Research

  3. Investigating astroglial bicarbonate transport in stroke-induced pH imbalance and injury in the brain

    Theparambil, S. (Principal Investigator) & Hawkes, C. (Co-Investigator)

    1/12/24 → 30/11/25

    Project: Research

  4. p27-FucciCA - A next-generation Quiescence and Cell Cycle indicator for functional studies in mouse

    Mort, R. (Principal Investigator)

    1/10/24 → 30/09/25

    Project: Research

  5. Preparation of a new vaccine to Influenza virus

    Rohaim, M. (Co-Investigator)

    Project: Research

  6. A new solution for an age-old problem: The pharmacological development of synergistic drug combinations for neglected tropical snakebite

    Hall, S. (Principal Investigator)

    Friends of Lancaster University in America INC

    1/10/24 → 30/09/25

    Project: Research

  7. The role of Gli similar transcription factors and the primary cilium in melanocyte development and melanoma phenotype switching

    Mort, R. (Principal Investigator) & Shih, B. (Co-Investigator)

    MRC Clinical Trials Unit

    1/10/24 → 31/03/28

    Project: Research

  8. Genome sequencing of 4 new isolates of Crithidia – an emerging parasite of humans

    Gatherer, D. (Principal Investigator) & Urbaniak, M. (Co-Investigator)

    1/10/24 → 30/09/25

    Project: Research

  9. NWCR summer studentship

    Kotsantis, P. (Principal Investigator)

    Project: Research

  10. High-resolution spatiotemporal mapping of brain and gut organismal death processes in C. elegans

    Benedetto, A. (Principal Investigator) & Shroff, H. (Principal Investigator)

    15/07/24 → 14/07/25

    Project: Research

  11. Designing bacterial gut communities to improve bee resilience to climate change

    Benedetto, A. (Principal Investigator)

    1/10/23 → 30/09/27

    Project: Research

  12. High-resolution spatiotemporal mapping of brain and gut organismal death processes in C. elegans.

    Benedetto, A. (Principal Investigator) & Shroff, H. (Principal Investigator)

    17/07/23 → 17/07/24

    Project: Research

  13. LU BBSRC 2024 International Partnership Fund

    Benedetto, A. (Principal Investigator)

    1/04/24 → 29/06/24

    Project: Research

  14. Investigating the Interplay of Organoselenides in Metal Homeostasis and the Gut-Brain Axis for General and Brain Health

    Benedetto, A. (Principal Investigator)

    1/07/24 → 1/07/27

    Project: Research

  15. North West Cancer Research Summer Studentships 2024

    Allinson, S. (Principal Investigator)

    1/07/24 → 30/09/24

    Project: Research

  16. Neddylation underlying Cell Differentiation and Biology in Trypanosomes, evolutionarily distinct human pathogens.

    Rojas Martinez, F. (Principal Investigator)

    Project: Research

  17. Optimisation and pre-clinical development of a KIFC1-PROTAC as a triple-negative breast cancer therapeutic

    Fielding, A. (Principal Investigator)

    1/05/24 → 10/06/27

    Project: Research

  18. Spot the Difference: The Cellular and Clonal Basis of Dalmatian and Mouse Spots

    Mort, R. (Principal Investigator)

    1/09/24 → 29/02/28

    Project: Research

  19. Mechansisms of volatile organic compound detection for whipworm diagnosis

    Hamilton, G. (Co-Investigator) & Worthington, J. (Principal Investigator)

    1/10/24 → 30/09/26

    Project: Research

  20. Investigation of IFI16 modulating molecules on Type I IFN inflammatory mediators following cytosolic DNA sensing or detection of nuclear DNA damage

    Unterholzner, L. (Principal Investigator)

    Kymera Therapeutics

    1/10/23 → 31/03/24

    Project: Research

  21. A comprehensive study of dysfunctional HDL to identify markers for cardiovascular disease status and risk

    Jackson-Jones, L. (Co-Investigator), Middleton, D. (Principal Investigator) & Allinson, S. (Co-Investigator)

    British Heart Foundation

    1/12/23 → 30/11/26

    Project: Research

  22. Rapid and Smart Diagnostic System for Infectious Diseases

    Pickup, R. (Co-Investigator), Pickup, R. (Co-Investigator) & Munir, M. (Principal Investigator)

    1/09/23 → 31/08/25

    Project: Research

  23. Securing Better Health, Ageing, and Wellbeing

    Broughton, S. (Principal Investigator)

    BBSRC

    15/08/23 → 31/03/25

    Project: Research

  24. GCRF Global IAA Institutional Award

    Apsimon, R. (Co-Investigator), Pickup, R. (Co-Investigator), Pickup, R. (Co-Investigator), Sutton, D. (Co-Investigator), Roy, M. (Co-Investigator), Tsekleves, E. (Co-Investigator), George, M. (Co-Investigator), George, M. (Co-Investigator), Armstrong, A. (Co-Investigator), Zografos, K. (Co-Investigator), Cin, M. (Co-Investigator), Alcock, K. (Co-Investigator), Decent, S. (Principal Investigator), Gillen, J. (Co-Investigator) & Decent, S. (Principal Investigator)

    Engineering and Physical Sciences Research Council

    Project: Research

  25. Targeting the gut-brain axis to improve animal resilience to a warming climate

    Benedetto, A. (Principal Investigator)

    17/04/23 → 31/07/23

    Project: Research

  26. Summer Studentships Biomedical and Life Sciences Lancaster University

    Allinson, S. (Principal Investigator)

    North West Cancer Research Fund

    1/06/23 → 30/09/23

    Project: Research

  27. Making the Dust Fly: Creating a million plus conversations in Ghana on home cleaning and superbugs

    Tsekleves, E. (Principal Investigator), Pickup, R. (Co-Investigator) & Darby, A. (Research Associate)

    1/03/23 → 29/02/24

    Project: Research

  28. WASHable II Impact Accelerator: Participatory design and community engagement Network on WASH in Lusophone and Francophone African Countries

    Tsekleves, E. (Principal Investigator), Pickup, R. (Co-Investigator) & Semple, K. (Co-Investigator)

    1/10/22 → 30/09/23

    Project: Research

  29. Control of Multiple Respiratory Viral Infections

    Rohaim, M. (Principal Investigator)

    3/06/19 → 30/06/22

    Project: Research

  30. Diagnostic challenges of mixed infections with major respiratory viruses

    Rohaim, M. (Principal Investigator)

    1/07/19 → 30/06/21

    Project: Research

  31. Establishing Field Data-Driven Universal Influenza Vaccine Platform in Egypt

    Rohaim, M. (Principal Investigator)

    30/12/18 → …

    Project: Research

  32. Continuous Evolution of Paramyxoviruses under Mixed Infection with Other Respiratory Viruses Egypt

    Rohaim, M. (Principal Investigator)

    25/10/15 → 1/10/17

    Project: Research

  33. Epithelial cells as sentinels in innate immunity

    Unterholzner, L. (Principal Investigator)

    The Royal Society

    1/10/23 → 30/09/24

    Project: Research

  34. REMIT: Reconstructing the In Vivo Evolution of Mesothelioma for Improved Therapy

    Jackson-Jones, L. (Principal Investigator)

    Cancer Research UK

    1/04/23 → 31/03/28

    Project: Research

  35. Talent and Research Stabilisation Fund 2022 (Leonie Unterholzner)

    Unterholzner, L. (Principal Investigator)

    21/11/22 → 31/03/23

    Project: Research

  36. Neuromodulation of death in Caenorhabditis elegans

    Benedetto, A. (Principal Investigator)

    18/03/19 → 30/04/22

    Project: Research

  37. Keeping macrophages alive: sensing IgM for survival

    Jackson-Jones, L. (Principal Investigator)

    1/04/19 → 1/10/21

    Project: Research

  38. Low-cost Portable Molecular Diagnostic Platform for Rapid Detection of Poultry Infectious Pathogens

    Munir, M. (Principal Investigator)

    1/04/21 → 30/09/21

    Project: Research

  39. Glucagon-like peptide-1; a hormone with a key role in mammalian helminth infection

    Worthington, J. (Principal Investigator)

    18/09/17 → 9/10/20

    Project: Research

  40. Field trials of synthetic sandfly sex pheromone to reduce human visceral leishmaniasis transmission

    Hamilton, G. (Principal Investigator)

    1/06/16 → 31/05/23

    Project: Research

  41. Molecular analysis of Ap4A mediated regulation of DNA replication and genome stability

    Copeland, N. (Principal Investigator)

    1/04/21 → 30/09/23

    Project: Research

  42. Volatile organic compound detection of intestinal whipworm infection

    Worthington, J. (Principal Investigator)

    King Abdulaziz University

    27/02/23 → 26/08/24

    Project: Research

  43. Mesothelioma Disease Evolution (CRUK Discovery Award supplement - REMIT)

    Jackson-Jones, L. (Principal Investigator)

    University of Cambridge

    1/02/23 → 31/01/24

    Project: Research

  44. Characterisation of perivascular astrocyte heterogeneity in human brains

    Hawkes, C. (Principal Investigator)

    Alzheimer’s Research UK

    1/01/22 → 31/12/23

    Project: Research

  45. Regulation of DNA repair and the innate immune response to radio- and chemotherapy by the DNA sensors cGAS and IFI16.

    Unterholzner, L. (Principal Investigator)

    North West Cancer Research Fund

    1/10/23 → 30/09/26

    Project: Research

  46. EPSRC CORE Equipment 2022 - Lancaster University

    Heathwaite, L. (Principal Investigator), Heathwaite, L. (Principal Investigator) & Allinson, S. (Co-Investigator)

    Engineering and Physical Sciences Research Council

    3/01/23 → 3/07/24

    Project: Research

  47. Modalities for Understanding, Recording and Integrating Data Across Early life (MURIDAE)

    Dawson, N. (Principal Investigator)

    Medical Research Council

    1/04/22 → 31/03/27

    Project: Research

  48. Understanding protein Ufmylation in Trypanosoma brucei

    Rojas Martinez, F. (Principal Investigator)

    The Royal Society

    17/10/22 → 16/10/23

    Project: Research

  49. STING signalling as link between DNA damaging therapies and innate immunity in bladder cancer

    Unterholzner, L. (Principal Investigator)

    Cancer Research UK Manchester Institute

    1/12/22 → 30/11/25

    Project: Research

  50. Impact of paternal obesity on offspring brain structure and function; implications for Alzheimer's disease

    Hawkes, C. (Principal Investigator) & Dawson, N. (Co-Investigator)

    Alzheimer’s Research UK

    1/01/23 → 31/12/26

    Project: Research

  51. Integrated Multiomics of Host-bacteria Interactions during C. elegans Gut Infections

    Zarate Potes, A. (Senior Research Associate)

    Project: Research

  52. Resolving the ‘dual-extraction bottleneck’ in transcriptomics for a deep understanding of host-microbe interactions

    Zarate Potes, A. (Principal Investigator)

    29/11/21 → 29/11/22

    Project: Research

  53. Horizon Europe: CLIMOS: Climate Monitoring and Decision Support Framework for Sand Fly-borne Diseases Detection and Mitigation with COst-benefit and Climate-policy MeasureS

    Hamilton, G. (Principal Investigator)

    UKRI

    1/09/22 → 31/08/25

    Project: Research

  54. Ubiquitin-like modifications underlying Cell Differentiation and Biology in Trypanosomes

    Rojas Martinez, F. (Principal Investigator)

    Project: Research

  55. Summer Studentships Biomedical and Life Sciences Lancaster University

    Allinson, S. (Principal Investigator)

    North West Cancer Research Fund

    1/06/22 → 30/09/22

    Project: Research

  56. Brazil-UK Partnership: New Bioactives for a Healthy Gut, targeting the gut microbiota

    Benedetto, A. (Principal Investigator) & Zarate Potes, A. (Co-Investigator)

    BBSRC

    1/06/22 → 31/05/25

    Project: Research

  57. Development of New 3D Cell Model to Perform Cytotoxicity Assays Using a Panel of Common Cancer Therapeutics and Compare Expression and Localisation of CIZl Biomarker (Megan Fraser)

    Copeland, N. (Principal Investigator)

    AandA Biotech Limited

    11/10/21 → 10/10/22

    Project: Research

  58. Understanding the Mechanisms of antibiotic induced weight loss and subsequent impact on Immunity (Megan Dooley)

    Worthington, J. (Principal Investigator) & Rigby, R. (Co-Investigator)

    Defence Science and Technology Laboratory (DSTL)

    1/01/22 → 31/12/24

    Project: Research

  59. Harnessing knowledge of lifespan biological, health, environmental and psychosocial mechanisms of cognitive frailty for integrated interventions

    Broughton, S. (Co-Investigator) & Holland, C. (Principal Investigator)

    BBSRC

    14/02/22 → 31/03/25

    Project: Research

  60. Tropism, Immunity and Pathology in African sleeping sickness (HAT-TIP)

    Worthington, J. (Co-Investigator), Dawson, N. (Co-Investigator), Urbaniak, M. (Principal Investigator) & Jackson-Jones, L. (Co-Investigator)

    The Dowager Countess Eleanor Peel Trust

    1/01/22 → 30/09/22

    Project: Research

  61. Cerebral glucose metabolism in the AppNL-G-F mouse model of Alzheimer’s disease

    Dawson, N. (Principal Investigator)

    Alzheimer’s Research UK

    9/06/21 → 8/06/22

    Project: Research

  62. Re-purposing GLP-1 receptor agonists for use as ani-helminth therapy

    Worthington, J. (Principal Investigator)

    Al Baha University

    1/01/22 → 31/12/23

    Project: Research

  63. FHM PhD Studentship - Repurposing gemfibrozil as a treatment for Alzheimer’s disease (£66,336)

    Parkin, E. (Principal Investigator), Gaffney, C. (Principal Investigator), Dawson, N. (Principal Investigator) & Benedetto, A. (Principal Investigator)

    Project: Research

  64. Building and optimisation of a microscope stage mounted stretch apparatus to investigate the role of physical forces in melanoblast behaviour

    Mort, R. (Principal Investigator) & Benedetto, A. (Co-Investigator)

    The Royal Society

    1/11/21 → 31/10/22

    Project: Research

  65. Re-purposing GLP-1 receptor agonists for use as ani-helminth therapy

    Worthington, J. (Principal Investigator)

    King Abdulaziz University

    1/01/22 → 31/12/23

    Project: Research

  66. The generation and validation of novel molecular biology tools for the study of 'protective protein' combination therapies in Alzheimer's disease

    Parkin, E. (Principal Investigator) & Mort, R. (Co-Investigator)

    The Dowager Countess Eleanor Peel Trust

    1/10/21 → 30/09/23

    Project: Research

  67. Nasal Cannabinoids in Covid-19/viral pathobiology

    Wright, K. (Principal Investigator) & Munir, M. (Co-Investigator)

    Gaea Science Ltd

    1/08/21 → 30/04/22

    Project: Research

  68. Defining the quality of good cholesterol from a combined structural and functional perspective

    Middleton, D. (Principal Investigator) & Allinson, S. (Co-Investigator)

    British Heart Foundation

    1/09/21 → 31/10/23

    Project: Research

  69. An ethical investigation into healthcare sustainability (Dr. Joshua Parker)

    Allinson, S. (Co-Investigator), Wilkinson, S. (Co-Investigator) & Appleby, J. (Principal Investigator)

    The Wellcome Trust

    1/10/21 → 28/02/25

    Project: Research

  70. NWCR Summer Studentship Renewal

    Allinson, S. (Principal Investigator), Parkin, E. (Co-Investigator), Copeland, N. (Co-Investigator), Fielding, A. (Co-Investigator), Rigby, R. (Co-Investigator) & Jackson-Jones, L. (Co-Investigator)

    North West Cancer Research Fund

    1/07/21 → 30/09/21

    Project: Research

  71. Functional Validation and Safety of Antimicrobial Properties of an Innovative Coating Material

    Munir, M. (Principal Investigator) & Pickup, R. (Co-Investigator)

    Viracoat Ltd

    1/07/21 → 30/06/25

    Project: Research

  72. Identifying and testing drug targets to delay human ageing using a fruitfly model.

    Clancy, D. (Principal Investigator), Palmer, D. (PhD Student) & Murali, P. (PhD Student)

    Project: Research

  73. Isolating small-molecule antimicrobials from insects

    Clancy, D. (Principal Investigator) & Dwarampudi, V. (PhD Student)

    Project: Research

  74. Local oxidised phospholipids within the pleural cavity: fuelling macrophage response during inflammation?

    Jackson-Jones, L. (Principal Investigator)

    Medical Research Council

    1/10/21 → 30/09/24

    Project: Research

  75. Heat shock signalling and response in African trypanosomes

    Urbaniak, M. (Principal Investigator)

    BBSRC

    1/12/21 → 30/11/25

    Project: Research

  76. The local immune response in malignant pleural mesothelioma

    Jackson-Jones, L. (Principal Investigator)

    British Lung Foundation

    1/07/21 → 31/12/24

    Project: Research

  77. HiWiN: High performance Wide spectral range Nanoprobe

    Mikhaylovskiy, R. (Co-Investigator), Kolosov, O. (Principal Investigator), Jarvis, S. (Co-Investigator) & Fullwood, N. (Co-Investigator)

    1/09/20 → 31/01/23

    Project: Research

  78. Evaluation of CoVID-19 Diagnostic Kits on Anonymized Human Samples

    Munir, M. (Principal Investigator)

    Katalyst Communications Ltd

    18/01/21 → 31/05/21

    Project: Research

  79. LIC has identified a structural variant of interest that is assumed to cause white spotting in the coats of bovine and wishes to undertake a model development project to demonstrate causality of this variant

    Mort, R. (Principal Investigator)

    Livestock Improvement Corporation Limited

    27/08/21 → 26/08/24

    Project: Research

  80. 3 Year Research PhD Studentship: Modulation of the innate immune responses by DNAzymes

    Unterholzner, L. (Principal Investigator)

    Defence Science and Technology Laboratory (DSTL)

    4/01/21 → 30/04/24

    Project: Research

  81. EPSRC Core Equipment 2020

    Jackson-Jones, L. (Co-Investigator), Nemeth, C. (Co-Investigator), O'Shea, P. (Principal Investigator) & Worthington, J. (Co-Investigator)

    Engineering and Physical Sciences Research Council

    14/11/20 → 13/05/22

    Project: Research

  82. Inflammatory responses against viruses

    Munir, M. (Principal Investigator)

    Aeirtec Limited

    8/11/21 → 30/01/23

    Project: Research

  83. MSI: Electroactive Biomaterials for Drug Delivery and Tissue Engineering - PhD studentship - Hend Abdelrady Mohamed Abdelmohsen

    Copeland, N. (Co-Investigator) & Hardy, J. (Principal Investigator)

    The Egyptian Bureau for Cultural and Educational Affairs

    1/10/20 → 30/09/24

    Project: Research

  84. MSI: Plasma-activated antimicrobial hydrogel therapy (PAHT) for combatting infections in diabetic foot ulcers

    Jaki, T. (Co-Investigator), Mateus, C. (Co-Investigator), Hollingsworth, B. (Co-Investigator), Allinson, S. (Co-Investigator) & Short, R. (Principal Investigator)

    Engineering and Physical Sciences Research Council

    1/02/21 → 30/11/24

    Project: Research

  85. MSI: Electroactive Biomaterials for Drug Delivery and Tissue Engineering - PhD studentship - Hend Abdelrady Mohamed Abdelmohsen

    Hardy, J. (Principal Investigator) & Copeland, N. (Co-Investigator)

    British Council (London)

    1/10/20 → 30/09/24

    Project: Research

  86. Analysis of the role of CIZ1 in maintenance of genome stability and recovery form DNA replication stress

    Copeland, N. (Principal Investigator)

    North West Cancer Research Fund

    1/11/20 → 31/12/25

    Project: Research

  87. Questioning Vaccination Discourse (Quo VaDis): A corpus-based study

    Semino, E. (Principal Investigator), Geyer, R. (Co-Investigator), Gatherer, D. (Co-Investigator), Brezina, V. (Co-Investigator) & Hardaker, C. (Co-Investigator)

    ESRC

    1/03/21 → 30/06/24

    Project: Research

  88. Releasing the cell cycle arrest with PROTACs to enhance DNA-damaging therapies

    Gadd, M. (Principal Investigator) & Allinson, S. (Co-Investigator)

    North West Cancer Research Fund

    1/10/20 → 31/12/24

    Project: Research

  89. MSI: High performance Wide spectral range Nanoprobe (HiWiN)

    Kolosov, O. (Principal Investigator), Jarvis, S. (Co-Investigator) & Fullwood, N. (Co-Investigator)

    Engineering and Physical Sciences Research Council

    8/02/21 → 7/09/24

    Project: Research

  90. Impact of Cannabis strain extracts on Inflammatory Bowel Disease models

    Wright, K. (Principal Investigator)

    MediCane Research and Development Ltd

    1/11/20 → 31/07/23

    Project: Research

  91. Mechanisms by which African tryanosomes sense and repsond to iron availability in the mammalian host

    Urbaniak, M. (Principal Investigator)

    BBSRC

    22/12/20 → 21/03/24

    Project: Research

  92. RECIRCULATE : GCRF: Driving eco-innovation in Africa:capacity-building for a safe circular water economy

    Paul, N. (Principal Investigator), Semple, K. (Co-Investigator), Martin, A. (Principal Investigator), Roy, M. (Principal Investigator), Pickup, R. (Principal Investigator), Dodd, I. (Principal Investigator), Rufino, M. (Principal Investigator), Larty, J. (Principal Investigator) & Jack, S. (Principal Investigator)

    1/10/17 → 31/12/21

    Project: Research

  93. Investigation of the impact of a novel Tau aggregation inhibitor peptide (RI-AG03) in a Drosophila model of Tauopathy

    Aggidis, A. (Principal Investigator)

    Alzheimer’s Research UK

    1/09/20 → 30/11/20

    Project: Research

  94. Development of CRISPR/Cas9 base Novel Poultry Vaccines against Endemic Viruses (PhD student: Julianne Vilela)

    Munir, M. (Principal Investigator)

    The British Council

    1/02/20 → 31/03/24

    Project: Research

  95. WASHable: Participatory design and community engagement Network on WASH in Lusophone and Francophone African Countries

    Pickup, R. (Co-Investigator)

    AHRC

    15/01/20 → 31/03/22

    Project: Research

  96. Peptide inhibitors of tau aggregation as a potential treatment for Alzheimer’s disease

    Allsop, D. (Principal Investigator), Fullwood, N. (Co-Investigator) & Fullwood, N. (Principal Investigator)

    Alzheimer’s Society

    1/02/20 → 31/10/22

    Project: Research

  97. Using the Asgard archaea to trace the natural history of protein homeostasis

    Robinson, N. (Principal Investigator)

    The Leverhulme Trust

    1/11/20 → 1/02/26

    Project: Research

  98. Dual morbidities in the developing world: The effect of obesity on susceptibility to nematode infection

    Worthington, J. (Principal Investigator)

    King Abdulaziz University

    1/12/19 → 30/11/21

    Project: Research

  99. Targeting perivascular innervation and vascular tone for improved clearance of ß-amyloid from the brain

    Hawkes, C. (Principal Investigator)

    Alzheimer’s Research UK

    1/10/19 → 31/08/20

    Project: Research

  100. A next generation Quiescence and Cell Cycle Indicator (QuCCi) for the refinement and reduction of animal usage in proliferation assays

    Mort, R. (Principal Investigator)

    National Centre for the Replacemnt Refinement and Reduction of Animals in Research

    7/01/20 → 6/07/23

    Project: Research

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