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Biomedical and Life Sciences

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  1. 2020
  2. Published

    Clearance of interstitial fluid (ISF) and CSF (CLIC) group—part of Vascular Professional Interest Area (PIA): Cerebrovascular disease and the failure of elimination of Amyloid-β from the brain and retina with age and Alzheimer's disease-Opportunities for Therapy

    Carare, R. O., Aldea, R., Agarwal, N., Bacskai, B. J., Bechman, I., Boche, D., Bu, G., Bulters, D., Clemens, A., Counts, S. E., de Leon, M., Eide, P. K., Fossati, S., Greenberg, S. M., Hamel, E., Hawkes, C. A., Koronyo-Hamaoui, M., Hainsworth, A. H., Holtzman, D. & Ihara, M. & 25 others, Jefferson, A., Kalaria, R. N., Kipps, C. M., Kanninen, K. M., Leinonen, V., McLaurin, J. A., Miners, S., Malm, T., Nicoll, J. A. R., Piazza, F., Paul, G., Rich, S. M., Saito, S., Shih, A., Scholtzova, H., Snyder, H., Snyder, P., Thormodsson, F. R., van Veluw, S. J., Weller, R. O., Werring, D. J., Wilcock, D., Wilson, M. R., Zlokovic, B. V. & Verma, A., 3/08/2020, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 12, 1, 7 p., e12053.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  3. Published

    Helminth Sensing at the Intestinal Epithelial Barrier—A Taste of Things to Come

    Faniyi, A. A., Wijanarko, K. J., Tollitt, J. & Worthington, J. J., 30/07/2020, In: Frontiers in Immunology. 11, 8 p., 1489.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  4. Published

    Drug-responsive autism phenotypes in the 16p11.2 deletion mouse model: a central role for gene-environment interactions

    Mitchell, E. J., Thomson, D. M., Openshaw, R. L., Bristow, G. C., Dawson, N., Pratt, J. A. & Morris, B. J., 23/07/2020, In: Scientific Reports. 10, 1, 11 p., 12303.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  5. Published

    Profiling cytotoxic microRNAs in pediatric and adult glioblastoma cells by high-content screening, identification, and validation of miR-1300

    Boissinot, M., King, H., Adams, M., Higgins, J., Shaw, G., Ward, T. A., Steele, L. P., Tams, D., Morton, R., Polson, E., Silva, B. D., Droop, A., Hayes, J. L., Martin, H., Laslo, P., Morrison, E., Tomlinson, D. C., Wurdak, H., Bond, J. & Lawler, S. E. & 1 others, Short, S. C., 23/07/2020, In: Oncogene. 39, 30, p. 5292-5306 15 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  6. Published

    Insulin/IGF-like signalling and brain ageing in Drosophila melanogaster

    Dravecz, N., 15/07/2020, Lancaster University. 284 p.

    Research output: Thesis › Doctoral Thesis

  7. Published

    Mitogen-activated protein kinase phosphatase-2 deletion modifies ventral tegmental area function and connectivity and alters reward processing

    Pytka, K., Dawson, N., Tossell, K., Ungless, M. A., Plevin, R., Brett, R. R. & Bushell, T. J., 1/07/2020, In: European Journal of Neuroscience. 52, 2, p. 2838-2852 15 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  8. Published

    Dynamic Programming Algorithms Applied to Musical Counterpoint in Process Composition: An Example Using Henri Pousseur’s Scambi

    Cochrane, L. J. & Gatherer, D., 30/06/2020, In: Preprints. 12 p.

    Research output: Contribution to Journal/Magazine › Journal article

  9. Published

    Modes of action of the archaeal Mre11/Rad50 DNA-repair complex revealed by fast-scan atomic force microscopy

    Zabolotnaya, E., Mela, I., Williamson, M., Bray, S., Yau, S. K., Papatziamou, D., Edwardson, J. M., Robinson, N. & Henderson, R., 30/06/2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 26, p. 14936-14947 12 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  10. Published

    Candida auris Phenotypic Heterogeneity Determines Pathogenicity In Vitro

    Brown, J. L., Delaney, C., Short, B., Butcher, M. C., McKloud, E., Williams, C., Kean, R. & Ramage, G., 24/06/2020, In: mSphere. 5, 3, 15 p., e00371-20.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  11. E-pub ahead of print

    Circular dichroism spectroscopy identifies the β-adrenoceptor agonist salbutamol as a direct inhibitor of tau filament formation in vitro.

    Middleton, D., Townsend, D., Hughes, E., Fullwood, N., Siligardi, G., Hussain, R. & Mala, B., 10/06/2020, (E-pub ahead of print) In: ACS Chemical Neuroscience.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  12. Published

    Diagnostic biomarkers for Alzheimer’s disease using non‐invasive specimens

    Paraskevaidi, M., Allsop, D., Karim, S., Martin, F. & Crean, S., 1/06/2020, In: Journal of Clinical Medicine. 9, 6, 19 p., 1673.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  13. Published

    FALC stromal cells define a unique immunological niche for the surveillance of serous cavities

    Jackson-Jones, L. & Benezech, C., 1/06/2020, In: Current opinion in immunology. 64, p. 42-49 8 p.

    Research output: Contribution to Journal/Magazine › Review article › peer-review

  14. Published

    Photoprotection conferred by low level summer sunlight exposures against pro-inflammatory UVR insult

    Felton, S. J., Shih, B. B., Watson, R. E. B., Kift, R., Webb, A. R. & Rhodes, L. E., 1/06/2020, In: Photochemical and Photobiological Sciences. 19, 6, p. 810-818 9 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  15. Published

    Evolutionary analysis of infectious bronchitis virus reveals marked genetic diversity and recombination events

    Rohaim, M. A., El Naggar, R. F., Abdelsabour, M. A., Mohamed, M. H. A., El-Sabagh, I. M. & Munir, M., 29/05/2020, In: Genes. 11, 6, 14 p., 605.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  16. Published

    Using the intrinsic growth rate of the mosquito population improves spatio-temporal dengue risk estimation

    Sedda, L., Taylor, B., Eiras, Á. E., Marques, J. T. & Dillon, R., 19/05/2020, In: Acta Tropica. 208, 11 p., 105519.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  17. Published

    Phosphoproteomic analysis of mammalian infective Trypanosoma brucei subjected to heat shock suggests atypical mechanisms for thermotolerance

    Ooi, C. P., Benz, C. & Urbaniak, M., 15/05/2020, In: Journal of Proteomics. 219, 9 p., 103735.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  18. Published

    COVID-19 outbreak: What are experts concerned about?

    Gatherer, D., Bermingham, R. & Others, 1., 11/05/2020, The Parliamentary Office of Science and Technology.

    Research output: Working paper

  19. Unpublished

    Characterising gut dysbiosis in rodent models relevant to psychiatric and neurodevelopmental disorders

    Ellis, J., 4/05/2020, (Unpublished) Lancaster University. 171 p.

    Research output: Thesis › Master's Thesis

  20. Published

    Effects of single-dose antipurinergic therapy on behavioral and molecular alterations in the valproic acid-induced animal model of autism

    Hirsch, M. M., Deckmann, I., Santos-Terra, J., Staevie, G. Z., Fontes-Dutra, M., Carello-Collar, G., Körbes-Rockenbach, M., Brum Schwingel, G., Bauer-Negrini, G., Rabelo, B., Gonçalves, M. C. B., Corrêa-Velloso, J., Naaldijk, Y., Castillo, A. R. G., Schneider, T., Bambini-Junior, V., Ulrich, H. & Gottfried, C., 1/05/2020, In: Neuropharmacology. 167, 11 p., 107930.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  21. Published

    Interactions between cytoplasmic and nuclear genomes confer sex‐specific effects on lifespan in Drosophila melanogaster

    Vaught, R., Voigt, S., Dobler, R., Clancy, D., Reinhardt, K. & Dowling, D. K., 1/05/2020, In: Journal of Evolutionary Biology. 33, 5, p. 694-713 20 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  22. Published

    MERTK is a host factor that promotes classical swine fever virus entry and antagonizes innate immune response in PK-15 cells

    Zheng, G., Li, L.-F., Zhang, Y., Qu, L., Wang, W., Li, M., Yu, S., Zhou, M., Luo, Y., Sun, Y., Munir, M., Li, S. & Qiu, H.-J., 1/05/2020, In: Emerging Microbes and Infections. 9, 1, p. 571-581 11 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  23. Published

    Three Creative Futures Methods for Imagining Life in a Post-Antibiotic World: Report on a Speculative Cross-Sector and Cross-Campus Conversation

    Braun, R., Curry, A., Gatherer, D., Kyne, K. & Spiers, E., 26/04/2020, Lancaster: Institute for Social Futures, Lancaster University, 15 p.

    Research output: Working paper

  24. Published

    16p11 Duplication Disrupts Hippocampal-Orbitofrontal-Amygdala Connectivity, Revealing a Neural Circuit Endophenotype for Schizophrenia

    Bristow, G. C., Thomson, D. M., Openshaw, R. L., Mitchell, E. J., Pratt, J. A., Dawson, N. & Morris, B. J., 21/04/2020, In: Cell Reports. 31, 3, 20 p., 107536.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  25. Published

    Identification of Complex Rumen Microbiome Interaction Within Diverse Functional Niches as Mechanisms Affecting the Variation of Methane Emissions in Bovine

    Martínez-Álvaro, M., Auffret, M. D., Stewart, R. D., Dewhurst, R. J., Duthie, C.-A., Rooke, J. A., Wallace, R. J., Shih, B., Freeman, T. C., Watson, M. & Roehe, R., 17/04/2020, In: Frontiers in Microbiology. 11, 659.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

  26. Published

    Stromal cells covering omental fat-associated lymphoid clusters trigger the formation of neutrophil aggregates to capture peritoneal contaminants

    Jackson-Jones, L., Smith, P., Portman, J., Magalhaes, M. S., Mylonas, K., Vermeren, M., Nixon, M., Henderson, B., Dobie, R., Vermeren, S., Denby, L., Henderson, N., Mole, D. & Bénézech, C., 14/04/2020, In: Immunity. 52, 4, p. 700-715 16 p.

    Research output: Contribution to Journal/Magazine › Journal article › peer-review

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